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Chapter03-Tissues- صيدلة

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Chapter 3

Tissues
Tissue = group of cells with similar
structure and function plus extracellular
substance (matrix)
There are four tissues in the body:
1) Epithelium

2) Connective

3) Muscular

4) Nervous
Functions of Epithelial Tissue

• Physical Protection

• Regulate Exchange

• Provides Sensation

• Produce Secretions
Characteristics of Epithelial Tissue
Epithelial Tissue

Tight Junctions

Desmosomes
Classification of Epithelia

1. Number of cell layers

A) Single layer of cells = Simple Epithelium

B) Several layers of cells (more than one) = Stratified Epithelium

2. Shape of Exposed (apical) cells

Squamous epithelium - Thin and flat.

Cuboidal epithelium - Short cube-shaped hexagonal boxes.

Columnar epithelium - Taller than it is wide.

Transitional epithelium - Changes shapes (from squamous to cuboidal).


Classification of Epithelia
Simple (1 cell layer) Stratified (more than 1 cell layer)
1) Simple Squamous Epithelium 5) Stratified Squamous Epithelium
Keratinized = Epidermis of skin
Glomerular capsule; Alveolus
Mesothelium; Endothelium Non-keratinized = esophagus, cheek

2) Simple Cuboidal Epithelium 6) Stratified Cuboidal Epithelium


Ducts of sweat glands
Renal tubules;
Thecal follicle (thyroid gland) Ducts of salivary glands

3) Simple Columnar Epithelium 7) Stratified Columnar Epithelium


Stomach, Small and Large Intestines Male urethra

4) Pseudostratified Ciliated 8) Transitional Epithelium


Columnar Epithelium Urinary bladder, ureter
Trachea, larynx, bronchi
A. Simple Squamous Epithelium

1.Simple squamous
epithelium is made up
of a single layer of
thin, flattened cells.
2.Because it is suited for
diffusion, it functions
in the exchange of
gases in the lungs
and lines blood and
lymph vessels as
well as body cavities.
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C. Simple Cuboidal Epithelium

1. Simple cuboidal epithelium consists


of a single layer of cube-shaped cells
with centrally located nuclei.

2. It functions in secretion and


absorption in the kidneys, and in
secretion in glands.
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Simple Cuboidal Epithelium
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D. Simple Columnar Epithelium

1. Simple columnar epithelium is made up of a


row of elongated cells whose nuclei are all
located near the basement membrane.
It may be ciliated.
2. It lines the uterus, stomach, and intestines
where it protects underlying tissues, secretes
digestive fluids, and absorbs nutrients.
3. In the intestine, these cells possess microvilli
that increase the surface area available for
absorption.
4. Mucus-secreting goblet cells can be found
among column cells.
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Simple Columnar Epithelium

E. Pseudostratified Columnar Epithelium

1. These cells appear layered due to the


varying positions of their nuclei within
the row of cells, but are not truly
layered.
2. Cilia may be present, along with
mucus-secreting globlet cells, that
line and sweep debris from
respiratory tubes.
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Pseudostratified Ciliated Columnar Epithelium

F. Stratified Squamous Epithelium

1. This type of tissue is made up of layers of


flattened cells that are designed to protect
underlying layers.
2. It makes up the outer layer of skin, and lines
the mouth, throat, vagina, and anal canal.
3. In the skin, outer layers of cells undergo
keratinization; however, this process does
not occur where tissues remain moist in the
throat, vagina, or anal canal.
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Stratified Squamous Epithelium

G. Stratified Cuboidal Epithelium


1. This tissue consists of two to
three layers of cuboidal cells
lining a lumen of the mammary
glands, sweat glands, salivary
glands, and pancreas.
2. Several layers of cells provide
greater protection than one
single layer.
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Stratified Cuboidal Epithelium
Stratified Cuboidal Epithelium

H. Stratified Columnar Epithelium


1. This tissue consists of several layers
of cells and is found in the vas
deferens, part of the male urethra,
and parts of the pharynx.
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Stratified Columnar Epithelium

I. Transitional Epithelium
1. Transitional epithelium is
designed to distend and return
to its normal size, as it does in
the lining of the urinary
bladder.
2. This design provides
distensibility and keeps urine
from diffusing back into the
internal cavity.
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Transitional Epithelium
Glands
• What are they?
structures that secrete substances onto a
surface, into a cavity, or into blood
• Exocrine glands:
- glands with ducts
- Ex. Sweat or oil glands
• Endocrine glands:
– no ducts (directly into bloodstream)
– Ex. Thyroid, thymus, pituitary glands, etc.
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Types of Exocrine Glands
• Simple:
no branches
• Compound:
many branches
• Tubular:
end of duct
• Alveolus:
sac-like structure

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Structural Classification of Simple and Compound Exocrine Glands
Modes of Secretion
Connective Tissue
Fluid Connective Tissue
1) Blood
2) Lymph

Connective Tissue Proper


1) Loose 2) Dense
1) Areolar 1) Regular
2) Adipose 2) Irregular
3) Reticular 3) Elastic

Supporting Connective Tissue


1) Cartilage 1) Bone
1) Hyaline 1) Spongy
2) Elastic 2) Compact
3) Fibrocartilage
Connective Tissue
Fluid Connective Tissue
Blood – in blood vessels and heart
Lymph – in lymph vessels and lymph nodes

Connective Tissue Proper


Loose Dense
1) Areolar - Papillary region of dermis, 1) Regular – Tendons, ligaments
around blood vessels, C.T. of membranes 2) Irregular – Joint capsules
2) Adipose - Hypodermis, eye sockets, Reticular region of dermis
renal fat capsule 3) Elastic – Elastic ligaments, walls of
3) Reticular - Spleen, lymph node, arteries, penile ligaments
capsule of liver and kidney

Supporting Connective Tissue


Cartilage
1) Hyaline – nose, trachea, larynx, Bone
Costal cartilage, articular cartilage 1) Spongy – inner portion
1) Elastic – epiglottis, external ear 2) Compact – outer portion
2) Fibrocartilage – intervertebral disc,
pubic symphysis, menisci
Areolar Tissue
Adipose Tissue
Reticular Tissue
Dense Regular Connective Tissue
Dense Irregular Connective Tissue
Elastic Tissue
Hyaline Cartilage
Elastic Cartilage
Fibrocartilage
Fluid Connective Tissue

Hematopoietic stem cells produce blood and lymph cells


Bone Tissue

Compact Bone
Spongy Bone

Muscle Tissues:
A. General Characteristics
1. Muscle cells, or fibers, can contract
and consist of three major types.

B. Skeletal Muscle Tissue


1. Skeletal muscle is attached to
bone and can be controlled by
conscious effort (voluntary).
2. The cells (muscle fibers) are
long and cylindrical, striated,
have many nuclei, and
contract from nervous
impulse.

C. Smooth Muscle Tissue


1. Smooth muscle tissue lacks
striations, is uni-nucleate, and
consists of spindle-shaped
cells.
2. This involuntary muscle is
found in the walls of internal
organs, and in the digestive
tract, blood vessels, and
urinary bladder.

D. Cardiac Muscle Tissue


1. Cardiac muscle tissue is found
only in the heart and consists
of branching fibers that are
connected to each other with
intercalated disks.
2. This involuntary muscle has a
single nucleus in each cell but
appears striated.

Muscle Tissue

Skeletal Cardiac Smooth


Nervous Tissues:
A. Nervous tissues are found in the
brain, spinal cord, and nerves.
B. Neurons, or nerve cells, conduct
nervous impulses while helper cells,
or neuroglia, support and nourish
the neurons.

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