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Orofacial Pain

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Orofacial Pain

● Orofacial pain:
○ Unpleasant sensation
■ Indicated risk of inorganic or tissue lesion
○ Accompanied by psychological connotations意思 and personified painful
threshold.
○ Pain was the most common symptoms that patients seek for help.
○ Diagnosis​:
1. Perform an appropriate PAIN anamnesis
2. Select the specific complementary test
○ Classification​:
1. Somatic Pain
a. Local: mucosal, periodontal, glandular...
b. Vascular orofacial pain
i. Migraine/ Cluster headache
ii. Facial migraine
iii. Inflammatory vascular Headache
iv. Other Vascular algias
v. Atypical odontalgia牙痛
vi. Referred pain
c. Masticatory pain

2. Neurogenic Pain
a. Trigeminal neuralgia
b. Facial neuralgia
c. Glossopharygeal neuralgia

3. Psycogenic Pain
● Migraine 偏頭痛
Migraine
● Severe headache with nausea噁心 and photophobia畏光
● Uncommon
● Adult, 女性較多
● 20 years (+- 10 years)

Aetiology ● Arterial dilatation動脈擴張


● Predisposal factors: ​Alcohol​, S
​ tress​, foods contain tyramine酪
銨: banana, chocolate ... contraceptive pill避孕藥

Clinical ✓ Recurrent, severe, ​Unilateral​, headache that last for hours or


features days (​4-72 hours​)
✓ Increases with physical activity or with head movement
✓ Preceding warning symptoms of visual, sensory, motor or
speech disturbances
✓ Photophobia
✓ Nauseaor vomiting

Diagnosis ➢ Clinical features


➢ Discard and organic diseases

Treatment ● Control predisposal factors


● Acute attack:
○ Salicylic acid 900mg
○ Paracetamol 1000mg
○ Ergotamine 2 mg + Cafeine 200 mg
○ Sumatriptan 50-100 mg orally max 300 /mg d o 6 mg
subcutaneous max12 mg day

● Migrainous neuralgia無預兆偏頭痛 or Cluster headache

Migrainous neuralgia無預兆偏頭痛 or Cluster headache 叢集性頭痛


● Horton’s headache
● Severe, ​One-sided pain
● Location: eye/periocular
● Short duration
● Autonomic ​homolateral同側​ signs
● Pain usually occurs at the same time of the day
● 10 to 25 cases per 100000 inhabitants per year
● 20-30 years
● 男性較多(3.6:1)

Pathogenesis ● Unknown
● Related to vascular changes
● Alcohol, Cocaine

Clinical Pain typically:


features ✓ Around the eyes
✓ Unilateral
✓ Occurs in ​cyclic attacks​, which last less than an hour
✓ Often awake patient at night
✓ Burning in character
✓ Watering of eye, nasal discharge and obstruction in the affected
side

Period of ● Recurrences in outbreak


crises ● Two main types:
1. ECH: Episodic Cluster Headache
■ Pain last for 4-8 weeks
■ Episodes發作 15 days pain-free
2. CRH: Chronic Cluster Headache
■ Daily crisis of pain > a year
■ 1-3 daily attacks

Diagnosis ➢ Clinical and neurologic examination


➢ Diagnosis tests
○ CT/MRI: non pathological findings

Vascular disorders

Treatment ● Patient education and ​trigger avoid


(Cluster 1. During a crisis
headache) ○ umatriptan 6 mg subcutaneously
○ Ergotamine 2mg oral
○ Oxygen inhalations 7l/min for 15 minutes

2. Prophylactic treatment
○ One daily crisis
■ Ergotamine 2 mg , 2 hours before the expected
crisis
○ Night crisis
■ Ergotamine 2mg , before going to bed
○ Two or more daily crisis
■ Ergotamine 1mg/8h/2 month
■ Verapamil 80mg/8h
■ Indomethacin 25mg/8h
■ Propanolol 40mg/12h

Classification
Neurogenic Pain

1. Trigeminal neuralgia: 2. Facial 3. Glossopharyngea


a. Essential (Classical): neuralgia l neuralgia
i. Typical
ii. Atypical
b. With known cause:
i. Post-traumatic
neuralgia
ii. Herpetic皰疹性
and post neuralgia
iii. Mulitiple sclerosis
iv. Benign trigeminal
neuralgia

● Trigeminal neuralgia

Trigeminal neuralgia

Clinical types
● Classical or Essential​: With not known cause
○ Typical: with classic features
○ Atypical: with atypical features
● Symptomatic
○ Due to trauma, viruses, drugs…

⭑ ​Classical Trigeminal neuralgia


Clinical features ✓ Unilateral​ pain
✓ Electric shock-like pain of abrupt onset and
termination
✓ Pain periods between 2 second and 2 minutes
✓ Periods of time with no pain, that varies from
person to person
✓ Restricted to the trigeminal nerve, one or more
branches
✓ In some patients triggered by chewing, talking,
swallowing, smiling or exposure to
temperatures change
✓ Normal sensory examination
✓ No pathological findings in complementary test

Pain characteristics ✓ Paroxysmal陣發性, electric shock-like pain


✓ Sudden onset
✓ High intensity
✓ The pain last between 2 second and 2 minutes
time
✓ When the pain disappears, the patient is with
no pain during the intercrisis periods隔離期間.

Triggers area ✓ Area of face, slight touch triggers pain


✓ Trigger areas are not always presented
✓ When triggered area is presented, usually an
area of a few millimetres in diameter and
located either in the infraorbital or menton area.

Pain location ✓ Restricted to the trigeminal nerve,


✓ The most common site: ​mandibular branch
✓ Trigger areas: gums, teeth
✓ Unilateral, never crosses the midline

Individual Pain characteristics ✓ Each patient has charcteristics pattern


✓ Painful crises are similar in intensity, location...

Sensory examination No pathological finding

Classical (Essential) Trigeminal neuralgia

Typical Atypical

Frecuency Seconds Minutes, Hours

Pain characteristics Intense Burning

Intensity Acute Moderate

Intercrises Not pain Without intercrises


Trigger areas Increase in pain ??

Sleep time NO YES

⭑Symptomatic trigeminal neuralgia


● Clinical features = classical trigeminal neuralgia
● Sweet ́ s criteria
● Other associated diseases:
○ Herpes viruses
○ Multiple sclerosis
○ Traumatism
○ Tumors

● Trigeminal neuralgia diagnosis


○ Clinical and neurologic examination
○ Additional tests.
■ CT/MRI: multiple sclerosis, tumors
■ Blood analysis: autoimmune process
■ Lumbar puncture
■ Evoked potentials: records of brain potential by stimuli
● Treatment
○ Drug treatment
○ Carbamacepine (Tegretol ®): start with 100mg/12 h, increasing by
100mg every three days until 400-1200mg/daily
→ Good results
○ Amitriptyline (Tryptizol ®, Norbitol ®, Deprelio ®): 30-75mg/d in three
doses
→ It causes dryness of mouth and urinary retention
○ Hydontoins ( Phenytoin ®): 300- 500 mg/d
○ Clonacepan ( Rivotril ®): 1,5 – 6 mg/d in three doses
○ Baclofen (Lioseral ®): start with 5mg/d increasing 5-10 mg/d every
three days up to 60 mg/d
Cluster headache Trigeminal headache

Age of onset 18-40 >= 40

Sex Men Men/Women

Attack duration 20-60 mins Seconds

Frequency 1-2 daily Many times per day

Location Periocular眼周 Lip & Jaws

Daily distribution Night time Day time

Trigger Alcohol/Cocaine Trigger areas

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