SCHOOL OF NURSING

DRUG STUDY
GUIMBAOLIBOT, RONA LIZA A.
BSN 2-9B
AGE: 47 y.o.
PATIENT’S NAME: Doza, Marliene Abueg BIRTHDAY: December 17, 1976
CHIEF COMPLAINT: Hemodialysis Session DATE OF ADMISSION: May 13, 2024
DIAGNOSIS: Chronic Kidney Disease (CKD) TIME OF ADMISSION: 1:50 PM
CO-EXISTING DISEASE: Onychomycosis

DRUG DATA CLASSIFICATION MECHANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING

ACTION RESPONSIBILITIES

Generic Name Antifungal The amphotericin Fungal infection Hypersensitivity. Adverse Reactions 1. Check culture and
Terbinafine products bind to sterols Chronic or active liver Terbinafine may cause sensitivity reports to
in the fungal cell disease. Lactation. abdominal pain, ensure that this is the
Brand Name membrane, altering jaundice, drug of choice for this
Lamisil permeability and Terbinafine can cause diarrhea, flatulence, patient.
allowing intracellular hepatic failure and nausea, anaphylaxis, 2. Ensure that the
Dosage components to leak out. temporary or permanent headache, rash, vision patient receives a full
250mg These drugs usually loss of smell and taste. disturbances, and liver course of antifungals as
inhibit fungal growth enzyme prescribed (may take up
Route and abnormalities. to 6 months for chronic
PO multiplication, but if infection), to get the full
the level is high beneficial effects.
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Frequency enough, the drugs can Indications and Dosage 3. Monitor IV sites to
OD x 6 wks destroy fungi. Azole Oral ensure that phlebitis or
antifungals, Tinea corporis, Tinea infiltration does not
Form nystatin, and cruris, Tinea pedis occur.
Film-coated tablet terbinafine interfere Adult: 250 mg once 4. Safety measures
with sterol synthesis in daily. Treatment (e.g.side rails and
Color fungal cells, damaging duration: 2-6 weeks assistance with
White cell membranes (tinea pedis), 4 weeks ambulation, antipyretics
and increasing (tinea corporis), 2-4 for fever and chills,
permeability. weeks (tinea cruris). temperature regulation for
fever, etc.) to protect the
Oral patient if CNS effects
Nail fungal infections (e.g. confusion,
Adult: 250 mg once daily disorientation, numbness)
for 6 weeks (fingernail) occur.
or 12 weeks (toenail). 5. Provide small,
frequent, nutritious
Topical/Cutaneous meals if GI upset is
Tinea pedis severe. Monitor
Adult: As 1% cream: nutritional status and
Apply to affected area arrange a dietary
1-2 times daily for 1 consultation as needed to
week (between toes) or 2 ensure nutritional status.
weeks (bottom or sides 6. Advise patient to
of feet). As spray: Spray report sore throat,
between the toes bid for unusual bruising or
1 week. As gel: Apply to bleeding, or yellowing of
affected area once daily eyes and skin, all of
for 1 week. which could indicate
Child: ≥12 years As hepatic toxicity; or
cream or spray: Same as severe nausea and
SCHOOL OF NURSING

adult dose. Dosage vomiting, which could

recommendations may interfere with nutritional
vary among countries or state and slow recovery.
individual products. 7. Educate patient on
Refer to country- or drug therapy to promote
product-specific understanding and
recommendations. compliance.

Topical/Cutaneous
Cutaneous candidiasis,
Pityriasis versicolor
Adult: As 1% cream:
Apply 1-2 times daily for
2 weeks.

Topical/Cutaneous
Tinea corporis, Tinea
cruris
Adult: As 1% cream:
Apply to affected area
1-2 times daily for 1-2
weeks. As 1% gel or
spray: Apply to affected
area once daily for 1
week.
Child: ≥12 years As 1%
cream or spray: Same as
adult dose. Dosage
recommendations may
vary among countries or
individual products.
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Refer to country- or
product-specific
recommendations.
Renal Impairment

Significant: Depression,
taste or smell
disturbance, severe
neutropenia,
agranulocytosis,
pancytopenia,
thrombocytopenia,
precipitation and
exacerbation of
cutaneous and systemic
lupus erythematosus,
exacerbation of psoriasis.
Eye disorders: Changes
in ocular lens and retina.
Gastrointestinal
disorders: Flatulence,
dyspepsia, nausea,
abdominal pain,
diarrhoea.
Metabolism and
nutrition disorders:
Decreased appetite.
Musculoskeletal and
connective tissue
disorders: Arthralgia,
myalgia.
SCHOOL OF NURSING

Nervous system
disorders: Headache.
Skin and subcutaneous
tissue disorders:
Pruritus, rash, urticaria.

Potentially Fatal:
Hepatic failure, serious
skin reactions (e.g.
Stevens-Johnson
syndrome, toxic
epidermal necrolysis,
erythema multiforme,
exfoliative dermatitis,
bullous dermatitis, drug
rash with eosinophilia
and systemic symptoms),
thrombotic
microangiopathy (e.g.
thrombotic
thrombocytopenic
purpura, haemolytic
uraemic syndrome).