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Hepatitis

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4.

Hepatitis
Hepatitis refers to an inflammatory condition of the liver. It is
commonly the result of a viral infection, but there are other
possible causes of hepatitis. Viral infections are the most
common cause of hepatitis. The World Health Organization
(WHO) estimates that 354 million currently live with chronic
hepatitis B and C globally.
Types of Hepatitis:
 Hepatitis A: Hepatitis A, caused by the hepatitis A virus
(HAV), is
the most common worldwide. The onset of hepatitis A usually
occurs 15 to 45 days after exposure to the virus, and some
infected
individuals, especially children, exhibit no clinical
manifestations. In
the majority of cases, no special treatment other than bed
rest is
required; most recover fully from the disease. Hepatitis A
does not
give rise to chronic hepatitis. The severity of the disease can
be
reduced if the affected individual is injected within two weeks
of
exposure with immune serum globulin obtained from persons
exposed to HAV. This approach, called passive immunization,
is
effective because the serum contains antibodies against HAV.
An
effective vaccine against HAV is available and is routinely
administered to children over two years of age living in
communities
with high rates of HAV.
 Hepatitis B: Hepatitis B is a much more severe and longer-
lasting
disease than hepatitis A. It may occur as an acute disease, or,
in
about 5 to 10 percent of cases, the illness may become
chronic and
lead to permanent liver damage. Symptoms usually appear
from 40
days to 6 months after exposure to the hepatitis B virus
(HBV).
Those persons at greatest risk for contracting hepatitis B
include
113
Dr. Tehseen Javed
Department of Environmental Sciences
intravenous drug users, sexual partners of individuals with
the disease, health care workers who are not adequately
immunized, and recipients of organ transplants or blood
transfusions. A safe and effective vaccine against HBV is
available and provides protection for at least five years.
Passive immunization with hepatitis B immune globulin can
also provide protection. Approximately 1 in 10 patients with
HBV infection becomes a carrier of the virus and may
transmit it to others. Those who carry the virus are also 100
times more likely to develop liver cancer than persons
without HBV in their blood

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