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INICET NOV 2024 PHARMA RECALL

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INICET NOV 2024 PHARMA RECALL

Dr Gobind Rai Garg

INICET NOV 2024 PHARMA RECALL

1. Which of the following drug binds to CD4 receptors and is used for both
CCR-5 as well as CXCR-4 tropic HIV?
a. Maraviroc
b. Ibalizumab
c. Fostemsavir
d. Tenofovir
2. Which of the following is a topical antifungal drug that is used for treatment
of onychomycosis?
a. Itraconazole
b. Griseofulvin
c. Caspofungin
d. Tavaborole
3. Match the correct antidote with the given drug toxicity?
a. Atropine: L-carnitine
b. Barbiturate: Fomepizole
c. Arsenic: Desferrioxamine
d. Benzodiazepine: Flumazenil
4. Which of the following anti-epileptic drugs act at the site marked by the
arrow?
INICET NOV 2024 PHARMA RECALL
Dr Gobind Rai Garg

a. Vigabatrin
b. Valproate
c. Ganaxolone
d. Tiagabine
5. Which antiepileptic drug specifically enhances the inactivation phase of
voltage-gated slow sodium channels, helping to stabilize hyperexcitable
neurons?
a. Phenytoin
b. Lamotrigine
c. Ethosuximide
d. Lacosamide
6. All of the following statements are true regarding thiopentone except?
INICET NOV 2024 PHARMA RECALL
Dr Gobind Rai Garg

a. It is highly lipid soluble drug


b. It is quickly concentrated in brain after IV administration
c. It shows the phenomenon of redistribution
d. It has short duration of action due to rapid renal excretion
7. Which of the anticancer drug acts as a PARP inhibitor?
a. Palbociclib
b. Rucaparib
c. Vorinostat
d. Ustekinumab
8. A patient presents with rheumatoid arthritis is not responding to anti-TNF
therapy. Which of the following is a JAK inhibitor that can be used for this
patient?
a. Vedolizumab
b. Etanercept
c. Sulfasalazine
d. Tofacitinib
9. Which of the following is drug of choice for infection due to Fasciola
hepatica?
a. Praziquantal
b. Albendazole
c. Triclabendazole
d. Mebendazole
10. Match the following drugs with the appropriate indication
A. Delirium tremens. 1. Acamprosate
B. Smoking cessation 2. Naloxone
C. Opioid overdose. 3. Oxazepam
D. Alcoholism 4. Vareniciline

a. A-1 B-4 C-2 D-3


b. A-3 B-4 C-2 D-1
c. A-2 B-4 C-1 D-3
INICET NOV 2024 PHARMA RECALL
Dr Gobind Rai Garg

d. A-3 B-2 C-4 D-3


11. Which of the following intravenous anaesthetic agent can result in adrenal
suppression?
a. Ketamine
b. Etomidate
c. Thiopentone
d. Propofol

12. A diabetic, hypertensive, and post-MI patient on atorvastatin, metoprolol,


and aspirin has lipid profile results of total cholesterol: 238 mg/dL,
triglycerides: 125 mg/dL, HDL: 50 mg/dL, and LDL: 160 mg/dL. Which
additional medications should be considered to optimize lipid management in
this patient?
1. Bemepedoic acid
2. Ezetimibe
3. Gemfibrozil
4. Evolocumab

a. 1,2 and 4
b. 1,2,3 and 4
c. 1 and 2
d. 1,3 and 4
13. All of the following drugs are used for treatment of uncomplicated malaria
except?
a. Artemether
b. Chloroquine
c. Primaquine
d. Sulfadoxine/pyrimethamine
14. Which of the following statement is true regarding fosphenytoin?
a. High doses can cause cardiotoxicity and hypotension
b. Safe dose is 250 mg/kg
INICET NOV 2024 PHARMA RECALL
Dr Gobind Rai Garg

c. It is given to all seizure patients in emergency irrespective of CNS


adverse effects and hypotension
d. High oral dose can result in cerebellar degeneration
15. A young male weighing 46 kg was treated with a drug. It has Vd of 6 L/kg
and clearance of 4.6 L/hour. What is the approximate half life of this drug?
a. 0.9 hours
b. 40 hours
c. 0.5 hours
d. 20 hours
16. Which of the following statement is true regarding pretomanid?
a. Its use is contra-indicated along with CYP 2C9 inducers
b. It can be used for resistant malaria
c. It is approved for treatment of XDR tuberculosis in combination with
Bedaquiline and linezolide
d. It acts by formation of reactive oxygen species
17. Which of the following statements regarding the causes of fall in diastolic
blood pressure is correct?
1. Loss of sympathetic outflow in lumbar region
2. Antagonism of beta 1 adrenergic receptors
3. Blockade of alpha 1 adrenergic receptors
4. Antagonism of beta 2 adrenergic receptors

a. 1,2 and 3
b. 1 and 3
c. 1,2,3 and 4
d. 3 and 4
18. Which of the following is correctly matched regarding the drug and its
receptor
1. Acetylcholine: A. Intracellular receptors
2. Insulin: B JAK-STAT pathway
3. Growth hormone: C. Ligand gated ion channels
INICET NOV 2024 PHARMA RECALL
Dr Gobind Rai Garg

4. Thyroxine: D. Intrinsic tyrosine kinase activity

a. 1-C, 2-D, 3- B, 4- A
b. 1- C, 2-B, 3-D, 4-A
c. 1-A, 2-D, 3-B, 4-C
d. 1-A, 2-B, 3-D, 4-C

19. Which of the following is not effective in preventing spread of COVID-19?


a. Cough etiquettes
b. Mask
c. Ivermectin
d. Vaccine

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