Bio Lo Gym 2 Cell Structure Function
Bio Lo Gym 2 Cell Structure Function
BIOLOGY
MODULE 2
2. 3. 4. 5. 6. 7.
Follow the instructions carefully. Answer the pretest before you start the lesson. Take note and record points for clarifications. Try to achieve at least a 75% level of proficiency in the tests. Work diligently and honestly. Answer the posttest.
2. Organisms whose cells do not have a nucleus are called a. plants c. eukaryotes b. organelles d. prokaryotes 3. What type of cell has these characteristics: contains DNA but no nucleus, contains flagella, ribosomes, cytoplasm, and a cell membrane. a. plant c. animal b. fungi d. bacteria 4. A cell with relatively few energy needs will probably have a relatively small number of a. ribosomes c. mitochondria b. lysosomes d. chromosomes
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5. In which of the following items would you expect to find cells? a. strawberry c. silver dollar b. eyeglasses d. plastic flower 6. Which of the following organelles transports materials inside the cell a. lysosome c. mitochondria b. chloroplast d. endoplasmic reticulum 7. Which of the following structures are common to both eukaryotic and prokaryotic cells? a. nucleus c. both b and c b. ribosomes d. cell membrane 8. Which of the following forms of life is not eukaryotic? a. a bacterial cell c. a plant cell like gumamela b. protist such as an amoeba d. a human cell such as a red blood cell 9. Plant cells often have a box-like shape because of the a. nucleus c. cytoplasm b. cell wall d. cell membrane 10. Which organelle has no membrane? a. vacuole b. lysosome c. ribosome d. chloroplast
11. Which of the following statements is always true? a. All cells have a cell wall. c. All cells contain a chloroplast. b. All cells contain a nucleus. d. All cells have a cell membrane. 12. A cell is observed to contain a nucleus, mitochondria and chloroplasts. information you can conclude that the cell is: a. a plant cell c. a bacterial cell b. an animal cell d. a prokaryotic cell 13. Which of the following is found in the nucleus? a. vacuoles c. mitochondria b. chloroplasts d. chromosomes 14. Digestive enzymes or hydrolytic enzymes are terms associated with a. ribosomes c. golgi apparatus b. lysosomes d. smooth endoplasmic reticulum 15. What site regulates what goes in and out of the cell? a. cell wall c. cell membrane b. vacuole d. nuclear membrane From this
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16. The site of ATP production and the site of photosynthesis are the _______________ and _________________. a. ribosomes and vacuoles c. mitochondria and chloroplast b. chloroplast and lysosome d. Golgi complex and chloroplast 17. Which is the brain of the cell? a. nucleus b. chloroplast c. golgi bodies d. mitochondria
18. A cell that lacks a nucleus and membrane bound organelles is known as a(an) ______________ cell. a. plant c. eukaryote b. animal d. prokaryote 19. What is the outermost boundary of an animal cell? a. the cell wall c. the cell membrane b. the cytoplasm d. the nuclear envelope 20. Which of the following is not true of chloroplasts? a. They synthesize sugar b. They contain pigments c. They are only found in plants d. They appear green because of the chlorophyll Got a perfect score? Check it out!
Key to answers on page 21.
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Formulation of the Cell Theory In 1838, Theodor Schwann and Matthias Schleiden were enjoying after-dinner coffee and talking about their studies on cells. It has been suggested that when Schwann heard Schleiden describe plant cells with nuclei, he was struck by the similarity of these plant cells to cells he had observed in animal tissues. The two scientists went immediately to Schwann's lab to look at his slides. Schwann published his book on animal and plant cells (Schwann 1839) the next year, a treatise lacking of acknowledgments of anyone else's contribution, including that of Schleiden (1838). He summarized his observations into three conclusions about cells: 1. The cell is the unit of structure, physiology, and organization in living things. 2. The cell retains a dual existence as a distinct entity and a building block in the construction of organisms. 3. Cells form by free-cell formation, similar to the formation of crystals (spontaneous generation). We know today that the first two principles are correct, but the third is clearly wrong. The correct interpretation of cell formation by division was finally promoted by others and formally announced in Rudolph Virchow's powerful statement, "Omnis cellula e cellula"... "All cells only arise from pre-existing cells". The modern principles of the Cell Theory include the following: 1. All known living things are made up of cells. 2. The cell is the structural and functional unit of all living things. 3. All cells come from pre-existing cells by division. (Spontaneous generation does not occur). 4. Cells contain hereditary information which is passed from cell to cell during cell division. 5. All cells are basically the same in chemical composition. 6. All energy flow (metabolism and biochemistry) of life occurs within cells.
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Landmarks in the Study of Cell Biology 1595 1626 1655 1674 1833 1838 1840 1856 1858 Jansen credited with first compound microscope Redi postulated that living things do not arise from spontaneous generation. Hooke described 'cells' in cork. Leeuwenhoek discovered protozoa. He saw bacteria some 9 years later. Brown descibed the cell nucleus in cells of the orchid. Schleiden and Schwann proposed cell theory. Albrecht von Roelliker realized that sperm cells and egg cells are also cells. N. Pringsheim observed how a sperm cell penetrated an egg cell. Rudolf Virchow (physician, pathologist and anthropologist) expounds his famous conclusion: omnis cellula e cellula, that is cells develop only from existing cells [cells come from preexisting cells] Kolliker described mitochondria. Miescher isolated DNA for the first time. Flemming described chromosome behavior during mitosis. Germ cells are haploid, chromosome theory of heredity. Golgi described the golgi apparatus. Svedberg developed the first analytical ultracentrifuge. Behrens used differential centrifugation to separate nuclei from cytoplasm. Siemens produced the first commercial transmission electron microscope.
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1941 1952 1953 1955 1957 1965 1976 1981 1987 1998 2000
Coons used fluorescent labeled antibodies to detect cellular antigens. Gey and co-workers established a continuous human cell line. Crick, Wilkins and Watson proposed structure of DNA double-helix. Eagle systematically defined the nutritional needs of animal cells in culture. Meselson, Stahl and Vinograd developed density gradient centrifugation in cesium chloride solutions for separating nucleic acids. Ham introduced a defined serum-free medium. Cambridge Instruments produced the first commercial scanning electron microscope. Sato and colleagues publish papers showing that different cell lines require different mixtures of hormones and growth factors in serum-free media. Transgenic mice and fruit flies are produced. Mouse embryonic stem cell line established. Creation of first knockout mouse which contains an artificially introduced mutation in their cells. Mice are cloned from somatic cells. Human genome DNA sequence draft
Prior to 1931 when the first electron microscope was developed, magnification of microscopes was limited to about 2 000 times. The small cell structures did not show up well or remained invisible. The electron microscope not only showed more detail of
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previously known parts of the cell but also revealed new parts. Cells and cell structures can now be examined at magnifications of up to 500 000 times and more.
The Street Sweepers The air we breathe is filled with dust, smoke, and even small bacteria. How come all these materials do not accumulate in the lungs and clog their passageways?
Key to answers on page 21.
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FIND OUT! Break a chicken egg into a dish, and look at the yolk. How large do you think is it? Estimate its width. Then use a metric ruler to measure the width of your chicken yolk cell. With a hand lens, observe the yolk closely. Other cells that can be seen easily are large fish eggs. Most cells are too small to be seen without the help of a microscope. Luckily, there are a few cells that can be seen with your naked eyes. Cells Have Structures Imagine that you could become smaller, down to the size of one micron (1 micron = 1/1000 inch). Your whole body would be smaller than the typical animal cell (see figure 2.2). Imagine, that you could step inside this cell and explore it. Find out some structures inside a cell. Be able to explore how bacterial cells are different from other cells such as plant and animal cells.
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cytoplasm
While cells differ in size and shape, most of them have common structures. The cells of animals, plants, and related organisms have three basic structures: Cell membrane the outer boundary of the cell. Nucleus the control center of the cell. Cytoplasm the material between the cell membrane and the nucleus. The first thing you see as you approach this cell is a thin sac-like membrane. The cell membrane covers the entire surface of the cell. As you take the imaginary step through the cell membrane, you immediately come in contact with the cytoplasm. Moving through the cytoplasm would be like moving through a jar of jelly.
A large, round nucleus is found somewhere in the cytoplasm. As the control center of the cell, the nucleus contains coded instructions for all of the cells activities. These coded instructions are stored on special structures called the chromosomes. Chromosomes are seen when a cell is reproducing. Just as the cell membrane covers the cell, a nuclear membrane covers the nucleus of the cell. It regulates the passage of materials in and out of the nucleus. Cytoplasmic Structures As you walk through the cytoplasm, you might bump into sausage-shaped bodies called mitochondria. They are commonly called the power houses of the cell. They trap the energy that results when food is broken down. Just as a power plant supplies energy to a business, mitochondria provide energy for the cell. Some types of cells are more active than others, thats why they can have more mitochondria. Analyze This Why might a muscle cell have more mitochondria than other cells? Muscle cells are always undergoing some type of movement. Muscles are also the ones exposed to strenuous activities like doing some household chores, running, walking, etc. Ever since you entered the cell, you have been walking on a network of canals called the endoplasmic reticulum. The endoplasmic reticulum extends from the nucleus to the cell membrane and takes up quite a lot of space in some cells. It moves material from one place to another place inside the cell. Ribosomes are the tiny dots you see on the edges of some of the endoplasmic reticulum. Some cells may contain millions of ribosomes. The actual building blocks of the cell (proteins) are made on the surfaces of these very tiny structures. In a manufacturing business, products are made, packaged, and moved to loading centers to be carried away. Structures called golgi bodies are the packaging and releasing structures of the cell. When something is released, it is given off by the cell. Applying a Concept An animal cell contains about 10 to 20 golgi bodies, while a plant cell contains several hundreds. Why do you think there is such a difference in the number of these structures in each cell type?
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Compare your answer to this: The fact that plants produce so many materials (food, oils, resins, etc.), they will be in need of more golgi bodies to store the said materials. Do you know that cells also produce wastes? In the cytoplasm, structures called lysosomes contain chemicals that digest wastes and worn-out/damaged cell parts. When a cell dies, chemicals in the lysosomes act to quickly break down the cell. In a healthy cell, the membrane around the lysosome keeps it from breaking down the cell itself. Plant cells do not have lysosomes. Many businesses have warehouses for storing products until they are sold. Vacuoles are storage areas in cells. They may store water, food, or waste products. In plant cells, vacuoles are big. In animal cells, vacuoles are small. Why do you think so? Feedback: Plants are said to be the producers of food in the environment. They may produce sugar, oil, nectar, etc. They are in need of bigger vacuoles to store such materials. You have just looked at the inner workings of an animal cell. Imagine now that you are taking a microscopic tour through the green plant cell below. You will find that some structures in this cell are quite different from the structures in an animal cell. Take note of them.
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The outer covering of the plant cell is not soft and thin. Instead, it is surrounded by a rigid/tough structure called the cell wall that supports and protects the plant cell. Once you pass through the cell wall, you see the same structures you saw in the animal cell. Hold on! Something new appears. The dark green bodies you see around you are chloroplasts. Substances inside the chloroplast help a green plant cell trap the suns energy and then produce food. Imagine you could take a trip into a tiny bacterial cell. Bacteria and blue-bacteria are quite different from other cells. They have fewer structures than plant or animal cells. However, they carry out all of the life processes that other cells carry out. You can see that a bacterium has a cell wall, a cell membrane, and cytoplasm. The chromosome material (nucleoid), which directs the cells activities, floats freely through the cytoplasm. The other structures are lacking.
Remember Cells need water to maintain health. Turning off the faucet every time you brush your teeth can conserve as much as five gallons of water. It will surely benefit a living organism somewhere!
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Challenge Make your own model of a cell at home. Prepare a small package of gulaman and pour it into a dish. Put common foods in the gelatin to represent cell structures. You could use lettuce or shredded carrots for endoplasmic reticulum and raisins for mitochondria. Be creative! Unmold your cell. And serve it to your family for salad or dessert.
Perfect?! If yes, fantastic! If not, just try and try again. Remember, no pain, no gain.
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Ooops! Take a deep breath. Relax for a while. What?! You want to move on? All right, your wish is granted! You may continue. Are you enjoying the module? I hope so. If yes, well and good! Hold on! We will now take the path to the next lesson. Keep on having fun as you learn!
Cells vary greatly in size, too. The bacteria that naturally live deep inside your body are very tiny. The ostrich egg cell below is 800,000 times bigger than the bacterial cells.
The living arrangement of cells also varies. The bacteria and other cells you might find in a drop of pond water live by themselves. These cells are one-celled organisms. You, your classmates, the cork trees and a variety of other organisms are many-celled organisms. Now that weve learned all about cells and their contents, its time to learn how cells are categorized. The first grouping is Prokaryotes and Eukaryotes. These are hard to pronounce Latin words, but their meanings are simple. Prokaryote refers to bacterial cells. Eukaryote refers to everything else. So, streptomyocin bacteria are prokaryote cells. Animals, plants and fungi (mushrooms) are made of eukaryote cells.
What are the differences between these cell types? A major difference between the two is the presence of membrane-bound organelles. Inside these cells we get things like mitochondria, golgi bodies, a nucleus, etc. They are clearly defined because they have internal membranes around them. The membranes hold them together. Prokaryote lacks these membranes, so consequently they dont have these organelles. Instead of a clearly defined nucleus with chromosomes, they have a single, circular piece of DNA. Thus, prokaryotes are simple and smaller than eukaryotes. What do they have in common? Well, while the prokaryotes do not have internal membranes, they do have a cell membrane just like the eukaryotes. They are also filled with cytoplasm. Finally, they have organelles which do not require membranes, (e.g. ribosomes). Imagine you could take a trip into a tiny bacterial cell. Bacteria and blue-bacteria are quite different from other cells. They have fewer structures than plant or animal cells. However, they carry out all of the life processes that other cells carry out. You can see that a bacteria has a cell wall, a cell membrane, and cytoplasm. The chromosome material, which directs the cells activities, floats freely through the cytoplasm. The other structures are lacking.
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The one-celled organism Amoeba proteus Figure 3.2 Some cell types.
Source: http://web.jjay.cuny.edu/~acarpi/NSC/13-cell.htm
The second cell grouping is Plants versus Animal cells. Both of these cell types are eukaryotes. This means they have a lot of organelles in common. One organelle they dont have in common is chloroplasts, which only plants have. Another organelle difference is the vacuoles. In animal cells the vacuoles are small and plenty. In the plant cells, there is a large central vacuole that occupies over 50% of the plant cells volume. This vacuole is filled with water and nutrients under pressure. The pressure helps maintain the plant cells rigid shape. The rigid shape results in plant cells looking rectangular as compared to the roundlike animal cells. While both cell types have cell membranes, the plant cells rigidity is further maintained by an additional cell wall outside the membrane.
Lets Summarize
1. Cells are amazing, variable, beautiful, and functionally superb. A concept of genius, they work alone or in groups with equal ease. 2. Cells are the basic units of life. All living things are made up of one or more cells. Organisms that exist as single cells are called unicellular and organisms that are made up of groups of cells working together are called multicellular. 3. Because all living things are made up of cells, and because we desire to understand ourselves and the other living things around us it makes sense to learn something about cells. 4. All living things are divided into two major groups depending on how their cells are set up. These two groups are the Prokaryotes and the Eukaryotes. 5. The basic structure of plant and animal cell is almost the same except for certain differences. The basic structure of a cell is composed of the following components. a. Cell Membrane b. Cytoplasm c. Nucleus However in plants, a rigid "Cell wall" is present outside the cell membrane or plasma membrane. 6. Cell Theory: All living things are composed of cells. Cells are the basic units of structure and function in living things. All cells come from preexisting cells.
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Whew! At last! You have finished studying the module. But, before you completely exit from this module, let us find out how much you learned from this material.
Posttest
Multiple Choice. Choose the letter of the best answer. Write the chosen letter on a separate sheet of paper. 1. Which of the following is NOT true of chloroplasts? a. They synthesize sugar b. They contain pigments c. They are only found in plants d. They appear green because of the chlorophyll 2. Which of the following organelles transports materials inside the cell a. lysosome c. mitochondria b. chloroplast d. endoplasmic reticulum 3. Which of the following is found in the nucleus? a. vacuoles c. mitochondria b. chloroplasts d. chromosomes 4. What type of cell has these characteristics: contains DNA but no nucleus, contains flagella, ribosomes, cytoplasm, and a cell membrane. a. plant c. animal b. fungi d. bacteria 5. What site regulates what goes in and out of the cell? a. cell wall c. cell membrane b. vacuole d. nuclear membrane 6. Digestive enzymes or hydrolytic enzymes are terms associated with a. ribosomes c. golgi apparatus b. lysosomes d. smooth endoplasmic reticulum 7. In which of the following items would you expect to find cells? a. strawberry c. silver dollar b. eyeglasses d. plastic flower 8. Where is the site of protein synthesis? a. nucleus b. lysosome c. ribosome d. mitochondria
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9. A cell with relatively few energy needs will probably have a relatively small number of a. ribosomes c. mitochondria b. lysosomes d. chromosomes 10. Organisms whose cells do not have a nucleus are called a. plants c. eukaryotes b. organelles d. prokaryotes 11. Which of the following structures are common to both eukaryotic and prokaryotic cells? a. nucleus c. both b and c b. ribosomes 12. A cell is observed to contain a nucleus, mitochondria and chloroplasts. information you can conclude that the cell is: a. a plant cell c. a bacterial cell b. an animal cell d. a prokaryotic cell 13. Which of the following statements is always true? a. All cells have a cell wall. c. All cells contain a chloroplast. b. All cells contain a nucleus. d. All cells have a cell membrane. 14. Plant cells often have a box-like shape because of the a. nucleus c. cytoplasm b. cell wall d. cell membrane 15. Which is the brain of the cell? a. nucleus b. chloroplast c. golgi bodies d. mitochondria From this
16. The site of ATP production and the site of photosynthesis are the _______________ and _________________. a. ribosomes and vacuoles c. mitochondria and chloroplast b. chloroplast and lysosome d. Golgi complex and chloroplast 17. Which of the following forms of life is NOT eukaryotic? a. a bacterial cell c. a plant cell like gumamela b. protist such as an amoeba d. a human cell such as a red blood cell 18. A cell that lacks a nucleus and membrane bound organelles is known as a(an) ______________ cell. a. plant c. eukaryote b. animal d. prokaryote 19. Which organelle has no membrane? a. vacuole b. lysosome c. ribosome d. chloroplast
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20. What is the outermost boundary of an animal cell? a. the cell wall c. the cell membrane b. the cytoplasm d. the nuclear envelope Got a perfect score? Check it out!
Key to answers on page 23.
Key to Answers
Pretest 1. c 2. d 3. d 4. c 5. a 6. d 7. b 8. a 9. b 10. c 11. d 12. a 13. d 14. b 15. c 16. c 17. a 18. d 19. c 20. c
Lesson 1
Activity 1.1 The Street Sweepers Lining the passageways are special cells that release a mixture of water, carbohydrates, and salts, called mucus. The particles of dust and dirt that are inhaled are trapped in this sticky mucus. Underneath this layer of mucus is another group of specialized cells that have cilia. As the cilia move, they create a sweeping action. This action keeps the most vital passageways in the body clean and open for business. Self-Test 1.1 1. Leeuwenhoek: discovered protozoa Hooke: described cells in cork Schleiden & Schwann: proposed cell theory Virchow: concluded that cells come from preexisting cells 2. The microscope opened up the world of the very small to biologists. It enabled scientists to discover that all living things are made up of cells.
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Lesson 2
Self-Test 2.1 Cell Structures: A Summary Animal cell Plant cell X / / / / / / / / / / / / / X / / / / X / / / /
Structures Cell wall Cell membrane Cytoplasm Mitochondria Ribosomes Endoplasmic reticulum 7. Golgi bodies 8. Lysosomes 9. Vacuoles 10. Chloroplasts 11. Nucleus 12. Chromosomes 1. 2. 3. 4. 5. 6. Self-Test 2.2
Bacterial cell / / / X / X X X X X X /
The body parts of the tadpoles change in response to the activity of the cells which is cell division. When cells divide, their number increases. Growth results when cells increase in number. The tails of the tadpole disappear due to the lysosomal activity. The lysosome, if you will recall, contains powerful chemicals which are used to digest or breakdown materials
Lesson 3
Activity 3.1 Feedback: One-celled organisms may have fewer or different structures from plant or animal cells. However, they carry out all of the life processes (reproduction, digestion, excretion, respiration, etc.) that other cells carry out. Self-Test 3.1 1. 2. 3. 4. 5. plant prokaryote prokaryote false true
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Posttest 1. c 2. d 3. d 4. b 5. c 6. b 7. a 8. c 9. c 10. d 11. b 12. a 13. d 14. b 15. a 16. c 17. a 18. d 19. c 20. c
References
Books: Alexander, G.; Balzer, L.; Collins, A.; Goodson, P.; Lauer, L.; Slesnick, I. Introduction to biology. Glenview, Illinois: Scott Foresman And Company. (1984).
Biggs, A.; Daniel, L.; Ortleb, P. (1994). Life science. Westerville, OH: Merrill Publishing Co., Mcmillan/McGraw-Hill. Campbell, N.A. Company. (1996). Biology. California: The Benjamin/Cummings Publishing
Miller, K.R. & Levine, J. (1991). Biology. New Jersey, Massachusetts: Prentice Hall. Hopson, J.L. & Wessells, N.K. (1990). Essentials of biology. USA: McGraw-Hill Publishing Company. Wong, H.K. & Dolmatz, M.S. (1986). Biology: The key ideas. New York, NY: Globe Book Company, Inc. Electronic Sources: Retrieved November 26, 2004 from http://www.cellsalive.com/cells/bactcell.htm Retrieved November 26, 2004 from http://webjjay.cuny.edu/~acarpi/NSC/13-cell.htm Retrieved November 26, 2004 from http://koning.ecsu.ctstateu.edu/Plants_Human/ unitlife.html Retrieved November 26, 2004 from http:www.sciencedaily.com/encyclopedia/Tadpole Retrieved November 26, 2004 from http://userpages.umbc.edu/~lruppi/project1index.shtml Retrieved December 21, 2004 from fig.cox.miami.edu/~cmallery/150/unity/cell.text.htm
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