Biochemistry and Molecular Biology
Biochemistry and Molecular Biology
Biochemistry and Molecular Biology
FIRST YEAR
Part A: 50 marks
1. Thermodynamics:
(a) First law of thermodynamics: Introduction, definitions, nature of heat and work, PV
work, maximum work, first law of thermodynamics - internal energy, enthalpy, molar heat
capacities, isothermal and adiabatic expansion.
(b) Thermochemistry : Exothermic and endothermic reactions, standard enthalpy of
formation,
thermochemical equations, reaction enthalpy - dependence on temperature, bond energies.
(c) Second law of thermodynamics: Thermodynamics - reversibility and irreversibility,
spontaneous processes, entropy, thermodynamic efficiency and Carnot’s theorem,
statements of second law, entropy changes - phase transition, heating, irreversible
processes. Third law of thermodynamics. Free energy - variation with temperature and
pressure, Gibbs-Helmholtz
equation, applications of thermodynamics in biochemistry, biochemical relevance of
classical thermodynamics, open systems.
2. Chemical equilibrium :
The nature of chemical equilibrium, law of mass action, equilibrium constant, relationship
between G and Keq, effect of temperature and pressure, Le Chattelier principle, equilibrium
reaction involving protons, coupling of reactions. Applications in living systems.
3. Chemical Kinetics : Definition, reaction rate, rate laws, zero-, first- and second-order reactions,
molecularity of a reaction, pseudo first order reaction, half-life, determination of order and rate
constant, effect of temperature on reaction rates. Theories of reaction rates - the collision theory,
the activated complex theory. Catalysis : Definition, types, characteristics of catalysts, activation
energy and catalysis.
4. Acids and bases : Bronsted-Lowry concept, Lewis concept, strengths of acids, weak acids and
bases, pH, buffer solutions. Henderson-Hasselbalch equation, buffering against pH changes in
biological systems, maintaining the pH of blood, acid-base indicators, acid base titration, choice
of a suitable indicator.
5. Properties of liquids (brief treatment): Introduction – the kinetic molecular description,
intermolecular forces in liquids, dielectric constant, surface tension, viscosity, diffusion, osmotic
pressure, phase rule, phase diagram of water, ionization of water, water as a reactant.
6. Spectrophotometry : Beer-Lambert law, standard curves, working principle of a
spectrophotometer.
Part B : 50 marks
1. Physico-chemical parameters for biomolecules:
Inter and Intramolecular interaction: covalent, ionic bond, hybrid orbitals, polarity
of bonds, electronegativity, dipole, hydrogen bonding, dihydrogen bonding,
hydrophobic interactions, Van der waals interaction.
2. Nature of bonding in organic molecules and in relation to biomolecules:
Delocalized chemical bonding-conjugation, cross conjugation, resonance,
hyperconjugation, bonding in fluorescences, tautomerism.
3. Reaction intermediates:
Formation, structure, stability and reactions of Carbocation, Carbanions, free
radicals, Nitrenes, Carbenes, Benzynes.
Books Recommended:
1) Essentials of Physical Chemistry
a. By : B.S. Bahl G.D. Tuli and A. Bahl
b. Publisher : S. Chand & Company Ltd.
2) Physical Chemistry with Application in Biological Systems
a. By : Ramond Chang
b. Publisher : Macmillan Publishers Co.
3) Text Book of Physical Chemistry
a. By : S. Glasstone
b. Publisher : D. Van Nostrand Company
4) Elements of Physical Chemistry
a. By. S. Glasstone and D. Lewis
b. Publisher : The Macmillan Press
5) Organic Chemistry
a. By : R.T. Morrison and R.N. Boyd
b. Publisher: Allyn and Bacon Inc.
6) Organic Chemistry
a. By : I.L. Finar Vol. 1 and Vol. 2
b. Publisher : English Language Book
c. Society and Longman Group. Ltd.
7) Organic Chemistry
a. By: H. Hart and R.d. Schuetz
b. Publisher: Houghton Mifflin Company
8) Contemporary Organic Chemistry
a. By: A. L. Ternay
b. Publisher: W.B. Sanders Company
9) Concepts In Modern Chemistry
a. By: P. Kavanah, J. Robbins and J. Oberkrieser
b. Publisher: Cambridge Book
Books Recommended:
1. Lehninger Principle of Biochemistry
By: David L., Nelson and Michael M. Cox.
Publisher: W.H. Freeman and Company, New York
2. Biochemistry
By: Lubert Stryer
Publisher: W.H. Freeman and Company, New York
3. Biochemistry
By: Donald Voit and Juldith Voit
Publisher: John Wiliy & Sons.
4. Cell and Molecular Biology
By: Gerald Karp
Publisher: John Willy & Sons
1. Introduction: Origin and evolution of life; differences between plants and animals;
modern concepts of classification of living organisms.
2. Microbiology:
a) Introduction to Viroids, Prions, Rickettsia and Mycoplasms.
b) Virus: Physical and chemical nature of phage, plant and animal viruses, multiplication of HIV
virus and economic importance.
c) Bacteria: Types, fine structure, reproduction and importance.
d) Fungi: Habitat, characteristics, classification up to class (Alexopoulos), reproduction, importance,
life history of Saccharomyces.
e) Cyanobacteria: Habitat, characteristics, structure, importance of Cyanobacteria .
f) Algae: Habitat, characteristics, classification up to class (Fritsch), reproduction, importance; life
history of Oeodogonium.
9. Plant Pathology: Concept of diseases in plants, causes, diagnosis, classification and importance of
plant diseases, symtomatology and control measures; forecasting of plant diseases.
Causal organisms, symptoms and control measures of brown spot of rice, stem rot of jute, citrus
canker and tungro disease of rice.
10. Economic Botany: Local and scientific names, parts used and importance of at least 8 prominent
plants of each of the following groups: (a) Food, (b) medicine, (c) timber, (d) fibre, (e) oil and (f)
vegetables. Cultivation and processing of tea and rubber.
Books Recommended:
1. Agrios, G.N. 1997 : Plant Pathology (4th ed.). Academic Press, London.
2. Bold, H.C. and
M.J. Wynne. 1978 : Introduction to the Algae, Prentice Hall, India
3. Hawker, Lilian, E. 1967 : Fungi, Hutchinson Univ. Library, Cambridge Univ. Press,
London.
4. Lawrence, G.H.M. 1951 : Taxonomy of Vascular Plants. The Macmillan Co. New York.
5. Pelczer, M.J., E.C.S. Chan : Microbiology: Concepts and Applications. McGraw Hill Book
Co. and N.R. Krieg. 1993 Inc. New York.
nvDm, XvKv|
1. Detail study including dissection (where necessary), mounting, drawing, description and
identification with classification of the following genera: 10
Cyanobacteria : N o s t o c , a n a b a e n a
Algae : Saccnaromyces and Accoboius
Bryophyte : Riccia and Marchantia
Pteridophyte : Selaginella, Christella
Gymnosperms : Cycas
Angiosperm : Poaceae and Fabaceae
2. Identification of the following genera with reasons: 06
4. Study of the symptoms and causal organisms of Brown spot of rice and stem rot of Jute.
....................05
5. Detailed taxonomic study of the families as included in the theory syllabus.
....................08
6. Study of plant and plant parts, and economic uses of angiosperms included in the syllabus.
....................06
7. Preparation of herbarium specimens of local plants and submission during examination.
....................05
8. Laboratory Note book. 05
Books Recommended:
1. Agrios, G.N 1997 : Plant Pathology (4th ed.). Academic Press, London.
2. Bold, H.C. and M.J.Wynne. 1978 : Introduction to the Algae, Prentice Hall, India
3. Devlin, M.R. and H.F. Witham.1986 : Plant Physiology (4th ed.). CBS Publishers and
Distributors, New Delhi.
4. Esau,K.1953 : Plant Anatomy. John Wiley & Sons, Inc., New York.
5. Goodwin, T.W. and E.I. Mereer. : Introduction to Plant Biochemistry (2nd ed.). Pergamon
Press.
6. Hawker, Lillin,E. 1967 : Fungi, Hutchinson Univ. Library, Cambridge Univ. Press,
London.
7. Kumar, H.D. 1995 : General Ecology, Vikash Pub. House, India.
8. Lawrence, G.H.M. 1995 : Taxonomy of Vascular Plants. The Macmillan Co. New
York.
9. Pelczer, M.J., E.C.S. Chan and
N.R. Krieg.1993 : Microbiology: Concepts and Applications. McGraw Hill
Book Co. Inc. New York.
10. Vashista, P.C. 1993 : Botany for Degree Students: Pteridophyta. S.C. Chand &
Co. Ltd. Ramnagar, New Delhi.
11. cvkv, †gv¯—dv Kvgvj
ivq, k¨vgj Kzgvi, 1986 : e¨envwiK Dw™¢`weÁvb, evsjv GKv‡Wgx,
XvKv|
12. AvLZvi“¾vgvb, g. : eskMwZ we`¨v, nvmvb eyK nvDR, XvKv|
13. AvLZvi“¾vgvb, g. 2000 : eeZ©b ev`, nvmvb eyK nvDR, XvKv|
14. Bmjvg, G. Gm. 1984 : eskMwZ we`¨vi g~j K_v, evsjv GKv‡Wgx,
XvKv|
15. Kg©Kvi, h`yjvj. 2000 : Dw™¢` kixi weÁvb, nvmvb eyK nvDR, XvKv|
16. Lvb, AvgRv` Avjx Ges
ZwiKzj Bmjvg : mœvZK Dw™¢` weÁvb 1g, 2q I 3q LÛ|
17. L›`Kvi gwbi“¾vgvb, 1994 : wjg‡bvjRx, XvKv wek¦we`¨vjq
cÖKvkbv, XvKv|
18. Rvgvb, Gg. G. 1975 : †Kvlwe`¨v, evsjv GKv‡Wgx, XvKv|
19. evmvi, Gg. G., Gg.G. nvmvb Ges : : Dw™¢` weÁvb, nvmvb eyK nvDR, evsjv
evRvi, XvKv|
g. iwdKzj Bmjvg. 2004
20. nvmvb, Gg. G. 1996 : evsjv‡`‡ki †flR Dw™¢`, Avkivwdqv eB Ni,
evsjv evRvi, XvKv|
21. nvmvb, Gg. G. Ges : Dw™¢` †kªYx web¨vm ZË¡ (3q ms¯‹iY), nvmvb
eyK nvDm, XvKv|
Gg. †K. Avjg. 1997
Introduction to Zoology: Definition and scope of zoology. Foundation of animal life: Level of organization
(protoplasmic, cellular, tissue, organ, organ system, organism, species, individual, population, community,
fauna, biota, ecosystem, biosphere, biodiversity. Cells: Cell and cell theory, structure and functions of cell
organelles. Gametogenesis: Spermatogenesis and oogenesis; placentation. Classification of animals: Animal
kingdoms; classification up to phyla on the basis of organization, symmetry, coelom and phylogeny; different
taxa and Linnean hierarchy and nomenclature.
Protozoa and non-chordates: General characteristics of the following protozoa and non-chordates phyla
with examples – Apicomplexa, Ciliophora, Porifera, Cnidaria, Ctenophora, Platyhelminthes, Gastrotricha,
Nematomorpha, Rotifera, Acanthocephala, Kinorhyncha, Loricifera, Priapulida, Supuncula, Pogonophora,
Tardigrada, Onychophora, Phoronida, Brachiopoda, Bryozoa/Ectoprocta, General and diagnostic
characteristics of the following phyla with examples – Sarcomastigophora, Annelida, Arthropoda and
Mollusca.
Type study of the following with their systematic position, habitats, external morphology, organ systems
such as digestion, movement, circulation, respiration, excretion, nervous, and reproduction; food and feeding
habits, mode of life and development –
a. Phylum Sarcomastigophora: Euglena
b. Phylum Apicomplexa: Eimeria
c. Phylum Ciliophora: Paramecium
d. Phylum Porifera: Scypha
e. Phylum Cnidaria: Obelia
f. Phylum Nematoda: Ascaris
g. Phylum Mollusca: Pila
h. Phylum Arthropoda: Prawn
i. Phylum Echinodermata: Astropecten
j. Phylum Hemichordata: Balanoglossus.
Human Physiology: Outline of the physiology of digestion, blood circulation, respiration, excretion and
reproduction; endocrine glands and their functions; vitamins and vitamin deficiency diseases.
Applied Zoology: Introduction to the major fields of applied zoology: Entomology, Fisheries Biology,
Wildlife Biology, and Parasitology. Agricultural pests: Major pests of rice, jute, sugarcane and stored grains.
Integrated fish farming: Types, poultry, livestock and paddy-cum-fish culture. Poultry farming: System of
poultry farming, diseases of poultry and their control, economic importance of poultry and their impacts on
socio-economic condition of Bangladesh.
2. Study of permanent slides: Whole mount, body parts and various cells and invertebrate
tissues (at least 10 slides to be studied)
a. Whole animals – representatives of protozoans, rotifers and arthropods.
b. Mouth parts of arthropods.
c. Parasites – nematodes and platyhelminths.
d. Different larval forms of invertebrates.
e. Histological slides of invertebrates.
5. Temporary mounting –
a. Brain of earthworm.
b. Salivary gland of cockroach.
c. Statocyst of prawn.
7. Animal physiology –
8. Class records.
Books Recommended:
1. C.P. Hickman and L.S Roberts. 1995. Animal Diversity Wm.C. Brown
2. L.S. Dillon. 1976. Animal Variety: An Evolutionary Account: Wm C. brown Company
Publishers, Dubuque, Iwoa.
3. J.D. Bernal. 1969. The Origin of Life. Weidenfeld and Nicolson, London.
4. E.E. Ruppert and R.D. Barnes. 1994. Invertebrate Zoology (6th edition). Saunders College
Publishing-harcourt Brace College Publishers, New York, London
5. C.P. Hickman. Integrated Principles of Zoology, C.V. Morsby Co. Inc., New York A.J. Marshal
and W.D. Williams. Text Book of Zoollogy Invertebrates, (edited the 7th edition of Text Book of
Zoology, Vol. I,T.J. Parker and W.A. Haswell)
6. N.J. Reigle. A Synoptic Introduction to the Animal Kingdom.
7. E.O. Wilson, T, Eisner and W.R. Brigges, Life: Cells, Organisms Populations. C.C.
Chatterjee Human Physiology Vols. I & II
8. W.H. Davson . A Text Book of General Physiology
9. G.L. Presser and P.A. Brown Comparative Animal Physiology
10. B.I. balinsky. An Introduction of Embryology
11. D. Dent. Insect Pest Management. Chapman and Hall, London.
12. P. Southgalte and J. Lucas (eds), 1998. Aquaculture Fish and Shellfish Farming Fishing News.
13. M. King. 1995. Fisheries Biology Assessment and Management. Blackwell Science.
14. C.G. Scalet. L.D. Flake and D.W. Willis. 1996. Introduction to Wildlife and Fisheries: An Integrated
Approach. W.H. Freeman.
15. TVR. Pillay. 1993. Aquaculture: Principles and Practices. Fishing News Books.
16. L.P. Pedigo. Entomology and Pest Management.
17. R.Wall and D. Shearer, 1997. Vetenerary Entomology. Chapman & Hall
18. V.G. Jingran and R.S.V. Pull in 1985. A Hatchery Manual for the Common, Chinese and Indian
Major Carps. ADB/ICLARM
19. ‡gvt Avãyi iv¾vK wgqv| 2007| †cvjwUª e¨e¯’vcbv| evsjv GKv‡Wgx|
20. ‡MŠZg ey× `vk| 2004| †cvjwUª Drcv`b| evsjv GKv‡Wgx|
21. GBP. Gg. †gv¯—dv | 1994| Lvgv‡i nuvm-gyiMx cvjb I †ivM-e¨vwai wPwKrmv|
evsjv GKv‡Wgx|
2. Proposal for undivided sovereign Bengal and the partition of the Sub Continent, 1947.
a. Rise of communalism under the colonial rule, Lahore Resolution 1940.
b. The proposal of Suhrawardi and Sarat Bose for undivided Bengal : consequences
c. The creation of Pakistan 1947 .
5. Military rule: the regimes of Ayub Khan and Yahia Khan (1958-1971)
a. Definition of military rules and its characteristics.
b. Ayub Khan’s rise to power and characteristics of his rule (Political repression, Basic democracy,
Islamisation)
c. Fall of Ayub Khan and Yahia Khan’s rule (Abolition of one unit, universal suffrage, the Legal
Framework Order)
7. The mass- upsurge of 1969 and 11 point movement: background,programme and significance.
mnvqK MÖš’
1. bxnvi iÄb ivq, evOvjxi BwZnvm, †`Õ R cvewjwks, KjKvZv 1402 mvj|
2. mvjvn& DwÏb Avn‡g` I Ab¨vb¨ (m¤úvw`Z), evsjv‡`‡ki gyw³
msMÖv‡gi BwZnvm 1947-1971, AvMvgx cÖKvkbx, XvKv 2002|
3. wmivRyj Bmjvg (m¤úvw`Z), evsjv‡`‡ki BwZnvm 1704-1971, 3 LÛ,
GwkqvwUK †mvmvBwU Ae evsjv‡`k, XvKv 1992|
4. W. nvi“b-Ai-iwk`, evsjv‡`k: ivRbxwZ, miKvi I kvmbZvwš¿K Dbœqb
1757-2000, wbD GR cvewj‡KkÝ, XvKv 2001|
5. W. nvi“b-Ai-iwk`, evOvwji ivóªwPš—v I ¯^vaxb evsjv‡`‡ki Af~¨`q,
AvMvgx cÖKvkbx, XvKv 2003|
6. W. nvi“b-Ai-iwk`, e½eÜzi Amgvß AvZ¥Rxebx cybcv©V, w`
BDwbfvwm©wU †cÖm wjwg‡UW, XvKv 2013|
7. W. AvZdzj nvB wkejx I W.†gvt gvneyei ingvb, evsjv‡`‡ki
mvsweavwbK BwZnvm 1773-1972, m~eY© cÖKvkb, XvKv 2013|
8. gybZvwmi gvgyb I RqšÍ Kzgvi ivq, evsjv‡`‡ki wmwfj mgvR cÖwZôvi
msMÖvg, Aemi, XvKv 2006|
9. AvwZDi ingvb, Amn‡hvM Av‡›`vj‡bi w`b¸wj: gyw³hy‡×i cÖ¯‘wZ ce©,
mvwnZ¨ cÖKvk, XvKv 1998|
10. W. †gvt gvneyei ingvb, evsjv‡`‡ki BwZnvm, 1905-47,
Zvgªwjwc, XvKv 2011|
11. W. †gvt gvneyei ingvb, evsjv‡`‡ki BwZnvm, 1947-1971, mgq
cÖKvkb, XvKv 2012|
12. ‰mq` Av‡bvqvi †nv‡mb, evsjv‡`‡ki ¯^vaxbZv hy‡× civkw³i
f~wgKv, Wvbv cÖKvkbx, XvKv 1982|
13. Aveyj gvj Ave`yj gywnZ, evsjv‡`k: RvwZiv‡óªi D™¢e, mvwnZ¨
cÖKvk, XvKv 2000|
14. ‡kL gywReyi ingvb, Amgvß AvZ¥Rxebx, w` BDwbfvwm©wU
†cÖm wjwg‡UW, XvKv 2012|
15. wmivR D`&`xb Avn‡g`, GKvˇii gyw³hy×: ¯^vaxb evsjv‡`‡ki
Af~¨`q, BmjvwgK dvD‡Ûkb, XvKv 2011|
16. RqšÍ Kzgvi ivq, evsjv‡`‡ki ivR‰bwZK BwZnvm, myeY©
cÖKvkb, XvKv 2010|
17. Harun-or-Roshid, The Foreshadowing of Bangladesh: Bengal Muslim League
and Muslim Politics, 1906-1947, The University Press Limited, Dhaka 2012.
18. Rounaq Jahan, Pakistan: Failure in National Integration, The University
Press Limited, Dhaka 1977.
19. Talukder Maniruzzaman, Radical Politics and the Emergence of Bangladesh,
Mowla, Brothers, Dhaka 2003.
20. ‡gmevn Kvgvj I Ckvbx PµeZx©, bv‡Pv‡ji K…lK we‡`ªvn,
mgKvjxb ivRbxwZ I Bjv wgÎ, DËiY, XvKv 2008|
21. ‡gmevn Kvgvj, Avmv` I Ebmˇii MYAfy¨Ìvb, weeZ©b, XvKv
1986|