Primary Headache Kuliah Stikes Upload
Primary Headache Kuliah Stikes Upload
Primary Headache Kuliah Stikes Upload
NYERI
Pengalaman sensorik & emosional yg tidak menyenangkan terkait kerusakan jaringan, baik aktual maupun potensial atau yang digambarkan dalam bentuk kerusakan tsb.
PATOFISOLOGI NYERI
1. Parenkim brain 2. Ependyma, pleksus choroid 3. Piamater, membrana arachnoidea & duramater 4. Bone skull
PATOFISIOLOGY Headache General : A. intracranial: 1. Iritasi meningen Ex: Meningitis Perdarahan Sub Arachnoid (SAH) 2. Penarikan or peregangan arteri intracranial: Tumor Absces Hematoma intracranial TIK : hidrosefalus, BIH TIK : post Lumbal Headache
3. Vasodilatasi arteri intra kranial Toksic caused infection With drawl caffein Hipoglikemia, Hipoksia, Hiperkapnea drug vasodilator Post attack Epilepsi Insufiensi sirculation brain
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Headache
PRIMER
Secunder
TTH
Migrain
Cluster Headache
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Primary Headache?
Preliminary Diagnosis
Atypical Features
Onset: sudden, abrupt, or progressively worsening Older: new onset and progressive headache, especially in
middle-age >50
Classification of headaches
Primary headaches Secondary headaches OR Idiopathic headaches OR Symptomatic headaches
THE HEADACHE IS ITSELF THE DISEASE NO ORGANIC LESION IN THE BEACKGROUND TREAT THE HEADACHE! THE HEADACHE IS ON LY A SYMPTOM OF AN OTHER UNDERLYING DISEASE TREAT THE UNDERLYING DISEASE!
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Throbbing
3 12 hours
Cluster
Boring, sharp
12 120 minutes
Dull, pressure
Lancinating
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Mass lesion
Subarachnoid hemorrhage, meningitis, cervical arthritis
Retinal hemorrhages
Cranial bruit Thickened, tender temporal arteryes Trigger point for pain Lid ptosis, third nerve palsy, dilated pupil Spasm and tenderness of Pericranial muscle
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No nausea or vomiting One or neither photophobia or phonophobia Not attributable to another disorder
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TTH Classification
Episodic <15 day/month Peripheral pain mechanism Tx NSAID, Parasetamol Chronic 15 day/month, 3 months Central pain mechanism Tx Amitriptilin
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TTH
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Treatment of TTH
Evidence A : multipel RCT B : 1 RCT C : Consensus Clinical effect : + few people improved ++ Some people improved +++ Most people improved
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Drug
evidence
Clinical effect
Role
Route
Ibuprofen+caffein
++
Antidepresan
Amitriptilin Maprotilin Mianserin A B B +++ + ++ preventive PO
Sulpride
Fluvoxamine
C
B
+
++
Muscle relaxants
Tizanidine Eperisone B B ++ ++ Acute&preventive PO
Others
Alprazolam Etizolam prochloperazine chlorpromazine B C C C ++ ++ ? ? 24 Acute IV Acute&preventive PO
-------- Ibuprofen (400 mg) + Caffein (200 mg) -------- Ibuprofen (400 mg)=Ketoprofen (50 mg)
-------- Ibuprofen (200 mg) = Ketoprofen (25 mg) = Naproxen (275 mg) -------- Aspirin/Paracetamol (500-1000 mg) + Caffein (30 mg) -------- Aspirin (500-1000 mg) = Paracetamol (500-1000 mg)
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Migraine
The most common disabling headache The most common headache visits Unknown causes
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Migraine Criteria
Unilateral Pulsating Moderate or severe intensity Aggravation by routine physical activity Nausea and/or vomiting Photophobia and phonophobia
1 of the following
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Japan 8%
Chile 7%
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Migraine
A. The Aura
B. The Attack
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Penatalaksanan migrain
1. 2. 3. Hindari pencetus Terapi abortif Non spesifik Spesifik Terapi preventif
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Pencetus Migraine
Kurang atau kebanyakan tidur Kelelahan Stres dan kecemasan Terlambat makan Perubahan hormonal Makanan (MSG, nitrit (pengawet) ,aspartam (pemanis buatan)) Cahaya terang
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ASA ibuprofen
Naproxen Parasetamol Diklofenac
A A
A A A
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TRIPTAN
Efikasi lebih baik dibanding ergot Sediaan obat di Indonesia sulit di dapat (hanya ada sumatriptan) Efek samping : nyeri dada, parestesi, fatik Kontra indikasi : Penyakit kardio, serebrovaskular, hipertensi, gagal ginjal, kehamilan dan laktasi
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Terapi prevensi migrain Konsensus Nasional III Nyeri Kepala PERDOSSI 2010
Obat Dosis mg/hari evidence
betablocker
metoprolol propanolol 50-200 40-240 A A
Anti epileptic
Valproic acid 500-1800 A
Topiramat
25-100
A
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Sefalgia sekunder
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stroke
Wanita 75 th di bawa ke IRD RS krn mendadak sakit kepala, hemiparese kiri
Trauma
Anak 15 th terkena pemukul baseball di pelipis. Sesaat setelah terkena pukulan ia tidak sadar sebentar 15 mnt lalu bangun lagi. Ia mengeluh sakit kepala namun keadaannya saat itu baik saat dibawa ke IRD. Empat jam kemudian saat diobservasi ia mengeluhkan sakit kepalanya bertambah hebat dan kejang. Pupil sebelah kanan midriasis
Infeksi
Pria 40 th , pengusaha mengeluh sakit kepala 2 bln, disertai demam sumer-sumer, sering diare dan sariawan .Ia mengkonsumsi narkoba berhenti sjk 1 th silam. Dibawa ke IRD oleh keluarganya krn bicara meracau.
Tumor
Wanita 35 th, sakit kepala 8 bln bertambah hebat terutama saat bangun dan bersin, memakai kontrasepsi suntik 3 bulan
Degenerasi
Wanita 79 th datang ke poli dengan keluhan sakit kepala hilang timbul 2 th.Sering lupa 3-4 th dan tidak mampu berbelanja lagi krn kesulitan melakukan perhitungan ringan. Sekarang sulit tidur dan sering terlihat seperti berbicara sendiri
ATAS PERHATIANNYA
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