K6 - Tetanus PEDIATRIC
K6 - Tetanus PEDIATRIC
K6 - Tetanus PEDIATRIC
(cause/origin
Distribution
Causative agent
Clostridium tetani
Spore-forming, anaerobic.
Not pathogenic to
humans and animals
by invasive infection
but by the production
of a potent protein
toxin
tetanus toxin or
tetanospasmin
The second exotoxin
produced is
tetanolysinfunction
not known.
Tetanus toxin
Methods of transmission
Symptoms
Types of tetanus:
local, cephalic, generalized, neonatal
Uncommon types:
Neonatal tetanus:
-
Methods of diagnosis
Clinical treatment
Antibiotics
Antitoxin
Anti convulsant
For attack seizure : 10-20 mg/iv or rectal
Evaluate seizure
Prevention
No immunity
Immunization DPT, DT, or TT
Scheme of diazepam
Came w/ seizure
Diazepam 10 mg IM
Seizure -
Seizure +
Diazepam 10 mg (max3 x)
Maintenance
20mg/kg/3 hr(8x)
Seizure -
Seizure +
ICU
Seizure -
Seizure +
48-72 hr
Evaluate dose
Decrease dose
10-15%
Destroy seizure