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    Clozapine Therapy Training FINAL 3-10-15

    Uploaded by

    Herry Hendrayadi
    This document provides training on Clozapine therapy. It states that Clozapine is used to treat schizophrenia and schizoaffective disorder. Regular blood testing is required due to risks of potentially fatal agranulocytosis and other serious side effects like seizures. Staff must ensure proper documentation and coordination between prescribers, pharmacies, and labs to safely administer Clozapine.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd

    Clozapine Therapy Training FINAL 3-10-15

    Uploaded by

    Herry Hendrayadi
    47 views23 pages
    This document provides training on Clozapine therapy. It states that Clozapine is used to treat schizophrenia and schizoaffective disorder. Regular blood testing is required due to risks of potentially fatal agranulocytosis and other serious side effects like seizures. Staff must ensure proper documentation and coordination between prescribers, pharmacies, and labs to safely administer Clozapine.

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    Clozapine Therapy Training FINAL 3-10-15 (1).pptx

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    This document provides training on Clozapine therapy. It states that Clozapine is used to treat schizophrenia and schizoaffective disorder. Regular blood testing is required due to risks of potentially fatal agranulocytosis and other serious side effects like seizures. Staff must ensure proper documentation and coordination between prescribers, pharmacies, and labs to safely administer Clozapine.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    47 views23 pages

    Clozapine Therapy Training FINAL 3-10-15

    Uploaded by

    Herry Hendrayadi
    This document provides training on Clozapine therapy. It states that Clozapine is used to treat schizophrenia and schizoaffective disorder. Regular blood testing is required due to risks of potentially fatal agranulocytosis and other serious side effects like seizures. Staff must ensure proper documentation and coordination between prescribers, pharmacies, and labs to safely administer Clozapine.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 23

    Clozapine

    Therapy Training
    3/10/2015
    Objectives
    What is Clozapine used to
    treat?

    What are the major side


    effects of Clozapine?

    Why is regular blood


    testing required?

    Who can administer


    Clozapine?
    Schizophrenia
    Brain disorder
    Chronic condition
    Requires lifelong
    treatment
    Schizoaffective Disorder
    Schizophrenia
    Plus
    Mood Disorder
    Major Depression
    Bipolar Disorder
    Clozapine
    Clozaril
    Used to treat
    Schizophrenia
    Schizoaffective
    Disorder
    Clozapine HCP Orders
    Must include
    Specific diagnosis for
    which Clozapine is
    prescribed
    Instructions to call
    prescribing HCP if 2 or
    more days of Clozapine is
    omitted
    Clozapine HCP Orders
    Any order change must be
    Communicated to all staff
    Documented in individuals
    record as a narrative note
    Documentation
    Clozapine HCP Orders

    Once HCP signs & dates


    Valid in program for
    One year [DDS]
    Ninety days [DMH/DCF]
    Common Side Effects
    Constipation
    Drooling
    Sleep disorders
    Increased sweating
    Weight gain
    Serious Side Effects
    Agranulocytosis
    Seizures
    Orthostatic Hypotension
    Bradycardia
    Syncope
    Myocarditis
    Cardiomyopathy
    Agranulocytosis
    Potentially fatal blood
    disorder
    Low White Blood Cell
    (WBC) count
    Great risk for infection
    Before starting Clozapine
    HCP will order lab tests
    WBC and ANC
    White Blood Count and Absolute
    Neutrophil Count

    May also be ordered as


    CBC with diff
    Complete Blood Count with
    Differential
    WBC and ANC Testing

    Baseline levels then,


    Weekly x6 months then,
    Biweekly x6 months then,
    Once every 4 weeks
    WBC and ANC Testing
    If Clozapine is DCd by
    the HCP
    Weekly labs for at least 4
    more weeks
    Pharmacy Requirement
    Current WBC & ANC levels
    Current is within 7 days
    Will only dispense enough
    Clozapine tablets until
    next blood test
    Pharmacy Requirement
    Pharmacy will not
    dispense Clozapine
    without current levels
    If lab value is more
    than 7 days
    Must be redrawn
    Responsibilities
    Certified staff must know
    Clozapine specific system
    to prevent running out of
    meds
    Upcoming lab work
    Ordering/reordering
    Medication Sheet
    MAP Consultants
    If a dose of Clozapine is
    missed contact the MAP
    Consultant
    If 2 or more days are missed,
    do not restart without
    consulting the prescribing
    HCP first
    Report Immediately
    Signs and Symptoms
    of infection
    Fever
    Weakness
    Lethargy
    Sore throat
    Confusion/Delirium
    Emergency Procedures
    Know
    Where to locate
    emergency
    policy/procedures
    When to call 911
    Who to notify in the
    event of emergency

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