Notes Full Biology (IGCSE) 2018
Notes Full Biology (IGCSE) 2018
Notes Full Biology (IGCSE) 2018
CHARACTERISTICS AND
CLASSIFICATION OF
LIVING ORGANISMS
• Organism: a living thing ranging in size from a single-celled microorganisms
to an elephant
• Cells: building blocks of which tissues are composed
Plants
Characteristics
- Multicellular
- Cells have nucleus, cell walls made of cellulose and contain chloroplasts
- Feed by photosynthesis
- May have roots, stems and leaves
Fungi
- Classified as plants
Characteristics
- Multicellular
- Have nuclei
- Have cell walls, not made of cellulose
- Do not have chlorophyll
- Feed by saprophytic or parasitic nutrition
Protoctista
Characteristics:
- Multicellular or unicellular
- Cells have nucleus
- Cells may or may not have a cell wall and chloroplasts
- Some feed by photosynthesis and others feeds on organic substances made by other organisms
Prokaryotes
Characteristics:
- Often unicellular
- Have no nucleus
- Have cell walls, not made of cellulose
- Have no mitochondria
Fungi
Protoctista
Prokaryotes
Viruses
• are not considered to be
alive
• Cannot move, feed,
excrete, show sensitivity,
grow or reproduce
• Consist of only a protein
coat surrounding a nucleic
acid (which can be either
RNA or DNA)
• Eg: smallpox, measles and
influenza
Classifying: Phylum vertebrates
Fish
Characteristics:
Reptiles
- Vertebrates with scaly skin
Characteristics:
- Have gills
- Vertebrates with scaly skin
- Have fins
- Lay eggs with rubbery shells (eg: snake)
Amphibians
Birds
Characteristics:
Characteristics:
- Vertebrates with moist, scale-less skin
- Vertebrates with feathers
- Adult often lives on land
- Forelimbs have become wings
- Larva has gills, adult has lungs (eg: frog)
- Lay eggs with hard shells
- Endothermic
Mammals
- Have a beak
Characteristics:
- Heart has 4 chambers
- Vertebrates with hair
- Have a placenta, diaphragm,
- young feed on milk from mammary gland
- Endothermic
- Heart has 4 chambers
- Have different types of teeth (incisors, canines, premolars &
molars) (eg: cat)
Classifying Phylum arthropods
Arachnids
Characteristics:
Characteristics:
- Several pairs of jointed legs
- Arthropods with four pairs of jointed legs
- Exoskeleton
- Breathe through gills called book lungs (eg: spider)
Insects
Myriapods
Characteristics:
Characteristics:
- Arthropods with three pairs of jointed legs
- Body consists of many segments
- Breathe through trachea
- Each segmented has jointed legs
- Body divided inti head, thorax and abdomen (eg:
grasshopper)
Crustaceans
Characteristics:
- Arthropods with more than four pairs of jointed legs
- Not millipede or centipedes
- Breathe through gills (eg: crab)
Classifying plants
Flowering plants divides by two:
Ferns (non-flowering)
Monocotyledon: have branching roots,
Characteristics: have leaves in the veins parallel to one
- Plants with roots, stems and leaves another, have 1 cotyledon in seeds
- Have leaves called fronds Dicotyledon: have tap root system, have
broad leaves and branching veins, have
- Do not produce flowers 2 cotyledon in seeds
- Reproduce by spores
Characteristics:
- Plants with roots, stems and leaves
- Reproduce sexually by means of
flowers and seeds
- Seeds are produced inside the ovary,
in the flower
CHAPTER 2:
CELLS
Animal cell Plant cell
Functions
Mitochondria
Cell membrane
Parts of the cell where energy is released from food
Holds the cell together and controls substances in the respiration process
entering and leaving the cell
Cell wall
Cytoplasm
Made of cellulose and gives the shape and support
Where many different chemical processes happen
Contains enzymes that control chemical reactions
Vacuole
Contains a liquid called a cell sap, which is water
Nucleus with various substances dissolved in it for storage
Contains chromosomes made up of genes Helps support the cell
Control a cell grows and works
Control the features that can be passed to the offspring Chloroplasts
Contain green pigment, chlorophyll which absorbs
the light energy that plants need to make food in the
process known as photosynthesis
Comparison of plant and animal cell
Plant cell Animal cell
Have a cellulose wall outside the cell Have no cell wall
membrane
Have cell membrane Have a cell membrane
Have cytoplasm Have cytoplasm
Have nucleus Have a nucleus
Often have chloroplasts containing Have no chloroplasts
chlorophyll
Often have large vacuoles containing cell sap Have only small vacuoles
Often have starch grains Never have starch grains, sometimes have
glycogen granules
Often in regular shape Often in regular shape
CELLS AND ORGANISMS
Cell – smallest structural and functional unit of an organism
Importance of water
- Metabolic reactions can only take place if the chemicals which
are reacting are dissolved in water
- Water is a solvent – if cells dry out, the reactions stop and the
organism dies
Eg: plasma, the liquid part of blood, contains a lot of water so
that substances like glucose can dissolve in it
- Water is also need to dissolve enzymes and nutrients in the
alimentary canal, so that digestion can take place
- The urea is dissolved in water, forming urea
Properties of carbohydrates, fats and
proteins
Carbohydrates Fats Proteins
Elements they C, H, O C, H, O C, H, O
contain
Smaller molecules of Simple sugar Fatty acids and Amino acids
which they are made (monosaccharides) glycerol
Solubility in water Sugars are soluble, insoluble Some are soluble and
polysaccharides are some are insoluble
insoluble
Why organisms need Easily available Storage of energy Making cells,
them energy (17 kJ/g) (39kJ/g), insulation, antibodies, enzymes,
making cell hemoglobin, also
membrane used for energy
Tests for starch, reducing sugars,
protein and fats
Starch
When iodine solution is mixed with
starch, it changes from brown to
dark blue.
This happens when even small
amounts of starch are present and
can be used as a simple test for the
presence of starch.
The food to be tested can be ground
up and mixed with distilled water.
A few drops of iodine solution are
then added to the sample.
A blue-black color indicates the
presence of starch.
Reducing sugars
Glucose and fructose are reducing
sugars.
Their presence can be detected
using Benedict’s solution.
If a precipitate forms when the
solution is added a prepared sample
containing the food to be tested and
heated to 95 C, this indicates the
presence of reducing sugars.
If there is significant amount of
sugar present the precipitate will be
an orange-red color.
A green precipitate means only a
small mount of sugar.
Protein
The Biuret test is used to check
for the presence of protein.
A small sample of the food under
test is placed in a test tube.
An equal volume of biuret
solution is carefully poured down
the side of the tube.
If the sample contains protein a
blue ring forms at the surface.
If the sample is then shaken the
blue ring disappears and the
solution turns a light purple.
Fats
Fats do not dissolve in water but
will in ethanol.
The test sample is mixed with
ethanol.
If fat is present it will be dissolved
in the ethanol to form a solution.
The liquid formed is poured into a
test tube of water, leaving behind
any solid that has not dissolved.
If there is any fat dissolved in the
ethanol it will form a cloudy white
precipitate when mixed with the
water.
CHAPTER 5:
ENZYMES
Biological catalysts
Catalyst – a substance that
increases the rate of a
chemical reaction and is not
changed by the reaction
Salivary amylase Salivary glands in the mouth Starch Maltose Needs a neutral environment
Gastric protease Walls of the stomach Protein Amino acids Works in strongly acid
conditions of the stomach
Bile salts (contains Liver Fats Emulsifies fats, making them Bile contains no enzymes, it
no enzymes) into smaller globules to acts to neutralize the acid
make digestion easier mixture from the stomach
Pancreatic juice Pancreas A complex mixture of
enzymes acting on all of the
main food groups
Amylase Starches Sugar
Nervous System
Has 3 components :
1. Sensory receptors- specialised cells which detect changes in internal
and external environment. Normally very specific. Mostly found in sense
organs. E.g rods and cones in the eyes, eardrum, skin, sensitive cells in
blood vessels.
2. Integrating centre – The CNS. The information from the receptors is
interpreted to bring appropriate response.
Effectors – Carry out response to the stimuli. Either muscles or glands.
Signals (impulses) are in the formed of electrochemical (electrical signals
within neurons & chemical between neurons) which is carried by specialized
nerve cells, neurons.
Receptor cells detect the stimuli, neurons will send the impulses to the CNS
which will process the information. Orders will be sent through other
neurons to the effectors to carry out appropriates responses.
Types of neurons – sensory, relay and motor.
Neurons consists of :
Motor neuron Sensory neuron
Relay neuron
Comparisons Between Sensory, Motor & Relay
TYPES OF RESPONSE (ACTIONS)
1. Voluntary action – an action taken as the result of a conscious
decision
2. Involuntary action – an action taken automatically without
conscious thought
Reflex arc - the route through the nervous system that impulses travel during a
reflex
How does reflex arc occur?
The Importance of Reflex Actions
1. Pupil reflex
Reflex arc:
Light Rods & ConesBrainIris muscles( circular & radial)Pupil diameter change
INTEGRATION
The image formed on the retina is inverted(upside
down ) and smaller.
The brain will correct the image and this is called
integration.
ENDOCRINE SYSTEM / HORMONAL SYSTEM
Hormone: chemical substance, secreted by endocrine
gland, carried by the blood, which alters the activity of one
or more specific target organs and is then destroyed by
the liver.
Examples : adrenaline, testosterone, estrogen, insulin
Effects of adrenaline
1. Increase in heart rate – more blood supply
2. Increase in rate & depth of breathing – more oxygen
3. Bronchioles become wider – more oxygen
4. Glucose will be released from the liver & muscles
5. Pupils will dilate
6. Skin becomes pale – more blood is redirected to the muscles
7. Less blood to the digestive system
8. Increase in sweating & hair will stand(goosebump)
Sepal Pistil
- enclose & protect the bud (Stigma)
Petal - receive pollen grains, has sticky
- attract insect to pollinate the flowers surfaces
(Style)
- protect the ovary
- join stigma to ovary, position stigma to
Stamen receive pollen grains
(anther) (ovary)
- produce pollen grain which carry the - contain ovules, surround and protect
male gametes the ovules, become fruits after
(filament) fertilization
- position the anther so the pollen grain (ovules)
are exposed to the pollinating agent - contain female gametes, become
seeds after fertilization
Pollination – the transfer of pollen grains from the male part of the
plant (anther of stamen) to the female part of the plant (stigma)
Seed germination
Mother’s milk
Contain all nutrients in the correct proportions at different stage
Colostrum- milk produced in the few days which contain mainly antibodies
Low in bacteria
Low cost, delivered at body temperature, no preparation, encourage. social bond between mother & baby
May have contraceptive effect
Formula milk
Modified cow’s milk
Contain saturated fatty acids – difficult to digest n inhibit calcium absorption
High in protein – baby’s kidney might not able to cope and can lead to brain
damage
Very high minerals esp. sodium which can lead to dehydration in baby
Lactose is very high – some babies have lactose intolerance
Expensive
Risk of contaminations – during preparation from the water used or unclean bottle
Birth control
INCREASING FERTILITY
FERTILITY TREATMENT
Reason for infertility 1. Artificial insemination
1. No eggs released An artificial insemination procedure uses a
thin, flexible tube (catheter) to put sperm
2. Low sperm count (spouse/donor) into the woman's reproductive
3. Block oviduct / sperm tract (vagina, cervix, uterus) around the time of
ovulation
duct
4. Failure of implantation
2. Use of hormones in fertility drugs
Fertility drugs are used when the woman
is not producing enough eggs. She is
given hormones, including FSH and LH,
that cause multiple release of eggs.
- The eggs can be allowed to be released
into the oviduct in the normal way.
The difference in
characteristics between
individuals of the same
species.
2 types of variations :
1. Continuous variation
2. Discontinuous
variation
Down’s Syndrome
extra chromosome 21 ( has 47 chromosome
altogether)
CAUSES OF VARIATIONS Characteristics : slanted eyes, smooth palm,
1. Environment – light , temperature, diet etc exceptionally happy, often with heart problems and
mental disabilities.
2. Genetics :
i. Meiosis – exchange of genes during alignment of Albino
homologous chromosomes (prophase 1) and very pale skin and hair, pink iris
independent assortment of chromosomes
(during metaphase 1) Gene for pigment mutated and produce an allele
(recessive) that does not code for melanin
ii. Fertilisation – any two gametes of opposite types
can fuse together so there are many possible
combinations of genes which may produce the GENETIC ENGNEERING
zygote
Genetic engineering is a process of taking a gene from
one species and putting it into another species
iii. Mutations
Permanent change that takes place spontaneously on
the genetic materials that cause changes in the
characteristics of the organism.
Can take place in both somatic cells (cancer) and
gametes. Mutation of somatic cells cannot be
inherited.
Agents that can cause mutations are called mutagens
e.g X-ray, ultraviolet and radioactive radiation.
Two types of mutations :
1. Chromosomal – change in the structure or number
of chromosome e.g Down’s syndrome, Turner’s
syndrome
2. Gene – Change in the sequence of nucleotides in
the DNA e.g Albinism, sickle cell anemia
• Human cells with genes for healthy insulin The importance of this process
are selected.
• A chromosome (a length of DNA) is • Diabetics need a source of insulin to control
removed from the cell. their blood sugar level. In the past cow insulin
has been used, but some people are allergic
• The insulin gene is cut from the to it. Human insulin produced from genetically
chromosome using restriction engineered bacteria will not trigger an
endonuclease enzyme. allergic reaction.
• A suitable bacterial cell is selected. Some • The insulin is acceptable to people with a
of its DNA is in the form of circular range of religious belief who may not be
plasmids. allowed to use insulin form animals such as
• All the plasmids are removed from the cows or pigs.
bacterial cell. • The product is very pure.
• The plasmids are cut open using the same • Human insulin can be made on a commercial
restriction endonuclease enzyme. scale, reducing costs.
• The human insulin gene is inserted into the
plasmids using ligase enzyme.
• The plasmid are returned to the bacterial
cell.
• The bacterial cell is allowed to reproduce
in a fermenter. All the cells produced
contain plasmids with the human insulin
gene.
SELECTION
There are more numbers of certain
individuals with particular characteristics
than others.
Can occurs due to :
1. Natural selection
2. Artificial selection
NATURAL SELECTION
Natural selection is the process by which
plants and animals that can adapt to
changes in their environment are able
to survive and reproduce while those that
cannot adapt do not survive. It gives the
greater chance of passing on of genes by
the best adapted organisms.
• Evolution is a change in species over a very Example:
long time (sometimes into different species.)
Natural selection is survival of the fittest. 1. Industrial melanism
What happens is:
A mutation occurs
• If the mutation is beneficial, the animal will
survive longer and reproduce more
• Some of its offspring will inherit the mutation
• These offspring will also have better chance of
survival, meaning they live longer and
reproduce more
• Over a long period of time this process is
repeated and gradually the mutation becomes
a common gene in a species and those with the - White moth used to be higher in population
mutation become the only ones, as those before industrialization takes place.
without cannot compete with those expressing
the mutated gene - After industrialization, tree barks were covered
with soot, the black moth were better
• Natural selection allows species to respond to camouflaged
the changes in the environment.
- The black moths’ population increased and the
white moth decreased
2. Antibiotic resistance bacteria 3. Sickle cell anemia
- mutation takes place in a few - Red blood cells become sickle
bacteria in a population shape when there is low
- These bacteria are resistant to an concentration of oxygen
antibiotic and are not killed. - There is less hemoglobin therefore
- These bacteria survived and less efficient at transporting
passed on the genes that helped oxygen
them survive - Less respiration takes place which
- The incident can be reduced by lead to less energy and the person
taking the antibiotics as will become fatigued easily
prescribed by the doctors. - The sickle-shaped red blood cells
- Pharmaceutical companies also will also blocked the capillaries
need to continue producing new which will stop the blood flow and
types of antibiotics eventually lead to death of the
affected tissue and the person will
in severe pain.
- The person who suffer from sickle
cell anemia will also suffer from
poor growth, more susceptible to
infections which might reduced
their life span
Natural selection in sickle cell anemia
- Even though sickle cell anemia is a ADAPTIVE RADIATION
disadvantage to the population but there is • This is where a common ancestor evolves
high percentage of sickle cell in areas with into a number of species. These have
malaria adaptations allowing them to occupy
- People with sickle cell is resistant to different niches.
malaria ax the parasites cannot survive in • A niche is the role of an organism in its
the red blood cell due to less oxygen community and consists of features such
- Homozygous sickle cell might die young as its feeding methods and habitat.
due to anemia • Speciation in honeycreepers
- Normal person might die due to malaria
- Heterozygous will survive both anemia and
malaria
- Heterozygous will then get married have
children and pass the trait to the their
children
- There is 25% chances of the offspring will
be homozygous recessive and normal
- 50% will be heterozygous will have the
advantage of resistance to malaria and do
not suffer from anemia.
Natural selections can lead to
evolution of new species due to
isolating barriers such as :
1. Geographical – mountain
range
2. Ecological -different habitats
or breeding areas, pH,
salinity.
• Reproductive - differences in
courtship behaviour, physical
differences which prevent
mating, or failure of gametes to
fuse
ARTIFICIAL SELECTION
Sucrase (invertase)
• Sucrase (invertase) converts sucrose into glucose and fructose. These two sugars
are much sweeter than sucrose. This means that food can be sweetened without
adding as much sugar, so they are used in low-calorie slimming products.
Lactose intolerance
• Lactose is a sugar commonly found in milk and milk products. Some people are
lactose intolerant which means that they cannot produce lactase - an enzyme that
digests lactose. A lack of lactase causes bacteria in the gut to ferment the
lactose, and this fermentation causes wind and diarrhoea.
• Lactose-free milk can be produced for people with lactose intolerance. This is
done using immobilised lactase. The lactase converts the lactose in the milk into
glucose and galactose, which are easier to absorb when the milk is consumed.
Penicillin
• Penicillin is made by the blue and
white penicillium molds.
Commercial penicillinis made by the
pencillium chrysogenum mold. The mold that
makes roquefort or brie cheese is
a penicillium. The hard white crust on brie
cheese is made of colonies of pencillium
camemberti.
• Penicillin is an antibiotic substance that kill
bacteria without harming human.
• Steps in making a deep tank fermenter to
extract pencillin:
1. Mix sugar, moldy bread and other nutrients
with warm water and put into a large glass
or baked enamel pot
2. Scrape blue-green mold from a moldy lemon
or orange into the water
3. Mix well and cover with an airlock
4. Keep in a warm place and let ferment 6 days
after first signs of fermentation begin
Genetic engineering
- Changing the genetic material of - Crop plants have been genetically
an organism by removing, modified to be resistant to
changing or inserting individual herbicides or insect pests. For
genes example, soya plants have been
genetically modified so that they
are not harmed when a herbicide
Different uses of genetic called glyphosate is sprayed onto
engineering: them. This means that farmer can
spray a field of these plants with
- Insulin – needed regularly by the herbicide and only the weeds
people with type 1 diabetes is now are killed. Cotton plants have been
produced by bacteria. Human genetically modifies so that they
insulin gene was inserted into the contain a substance called Bt
bacteria and they are now grown in which is toxic to insects. Insect
huge vats pests, such as the cotton boll
weevil are killed if they eat the
cotton plants. This reduces the use
of pesticides.
- Rice has been genetically modified to produce much more
vitamin A than a normal rice. The rice grains are yellow, so
it is called Golden rice. Lack of vitamin A is a big problem
for children in some parts of the world, particularly where
their diet mainly consists of white rice. Severe vitamin A
deficiency can cause blindness and is thought to kill more
than one million people each year. Growing and eating
Golden rice rather than ordinary rice could be a big help in
solving this problem.
• As human population continues to grow we are having a greater and greater impact upon
the world ecosystem
Agriculture
Increased food production
Intensive farming trying to produce as much food as possible from the land available.