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    Spotters GP, ANS

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    jafrin22
    Gen. Pharmacology, ANS This document discusses various pharmacology concepts including: narrow therapeutic index drugs like phenytoin that require therapeutic drug monitoring; competitive and noncompetitive antagonism; black box warnings such as for sodium valproate use in children under 3; drugs that cause delayed effects, repeated dose effects, or require infusion pumps; and neuromuscular blocking agents used for procedures. Specific drugs are discussed in the context of their indications, mechanisms, kinetics, interactions and more.

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    Spotters GP, ANS

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    jafrin22
    48 views24 pages
    Gen. Pharmacology, ANS This document discusses various pharmacology concepts including: narrow therapeutic index drugs like phenytoin that require therapeutic drug monitoring; competitive and noncompetitive antagonism; black box warnings such as for sodium valproate use in children under 3; drugs that cause delayed effects, repeated dose effects, or require infusion pumps; and neuromuscular blocking agents used for procedures. Specific drugs are discussed in the context of their indications, mechanisms, kinetics, interactions and more.

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    Gen. Pharmacology, ANS This document discusses various pharmacology concepts including: narrow therapeutic index drugs like phenytoin that require therapeutic drug monitoring; competitive and noncompetitive antagonism; black box warnings such as for sodium valproate use in children under 3; drugs that cause delayed effects, repeated dose effects, or require infusion pumps; and neuromuscular blocking agents used for procedures. Specific drugs are discussed in the context of their indications, mechanisms, kinetics, interactions and more.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    48 views24 pages

    Spotters GP, ANS

    Uploaded by

    jafrin22
    Gen. Pharmacology, ANS This document discusses various pharmacology concepts including: narrow therapeutic index drugs like phenytoin that require therapeutic drug monitoring; competitive and noncompetitive antagonism; black box warnings such as for sodium valproate use in children under 3; drugs that cause delayed effects, repeated dose effects, or require infusion pumps; and neuromuscular blocking agents used for procedures. Specific drugs are discussed in the context of their indications, mechanisms, kinetics, interactions and more.

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    Spotters

    Gen. Pharmacology, ANS


    1. MENTION ONE DRUG HAVING NARROW
    THERAPEUTIC INDEX PHENYTOIN
    2. HOW TO MONITOR DRUG DOSAGE FOR THE SAID
    DRUG? TDM
    COMPARE DRUGS B & D IN TERMS OF EFFICACY WITH
    RESPECT TO DRUG A

    DRUG ‘B ‘ IS EQUALLY EFFICACEOUS AS DRUG ‘A’


    DRUG ‘ D’ IS LESS EFFICACEOUS THAN DRUG ‘ A’
    1. What is effect of drug C on drug A
    2. Give one example

    Noncompetitive antagonism
    Diazepam- Bicuculine
    Compare drugs B & D in terms of potency with
    respect to Drug A

    Drug D is more potent than


    Drug A
    Drug B is less potent than Drug
    1. What is effect of Drug B on Drug A?
    2. Give one example

    Competitive
    Antagonism
    d TC with ACh
    1. What is black box warning?
    2. What is the black box warning for the
    use of sodium valproate in children < 3
    years of age. FULMINANT HEPATITIS
    1. Mention the drug that can cause this effect
    THALIDOMIDE
    2. Mention one current indication for this drug
    ENL, CANCER CACHEXIA
    1. Mention two drugs
    which acts by this
    mechanism
    THYROXINE, VIT D
    2. What is the relation
    between this
    mechanism of action
    and onset of effect
    DELAYED ONSET
    1. Mention one drug example each which
    follows A & B type of elimination kinetics
    2. What happens to clearance of the drug ‘a’
    when the dose is increased?

    A B

    1. A- ETHYL ALCOHOL, B- ANY DRUG


    CLEARANCE DECREASES
    1. What is this effect called as ?
    2. Mention two drugs producing such effect

    Repeated administration
    of drug

    TACHYPHYLAXIS
    TYRAMINE, AMPHETAMINE. EPHEDRINE,
    DOBUTAMINE
    1. Identify this drug delivery system
    2. Mention two drugs administered by using
    this device

    INFUSION PUMP
    INSULIN, DOBUTAMINE , DOPAMINE
    1. Identify the naturalBotulinum
    toxin X
    Toxin
    To prevent facial
    2. Mention one usewrinkles
    for it

    Inhibition
    X
    Pheochromocytoma
    1. What can happen if
    the patient is
    administered
    propranolol without
    any other medication
    HYPERTENSIVE
    EMERGENCY
    2. Name a drug that
    must be given before
    giving propranolol
    PHENTOLAMINE
    1. Name the drug obtained from this
    source.
    2. Mention 2 of its uses.
    Atropine
    Preanaesthetic
    medication
    OP Poisoning
    X 1. Identify drug X
    Norepinephrine

    2. Explain its effect


    on pulse rate
    Reflex bradycardia
    X
    Adrenaline
    2. Mention one
    use of the drug
    Anaphylactic
    Shock
    ANGLE CLOSURE GLAUCOMA
    1. Name a drug that
    may be used both
    orally & IV for this
    condition.

    2. Name one more


    condition for which
    it may be used

    1.Acetazolamid
    e
    2.Acute
    Mountain
    1. Identify the toxin being usedd-TC
    here
    2. Name the shortest acting drug with
    Neostigmine
    similar mechanism of action
    1. Mention a drug used for treatment
    2. Identify drug X used in diagnosis

    Myasthenia
    Gravis

    Pyridostigmine
    Edrophonium

    Before drug X After drug X


    as an
    O.P.Compound
    insecticide (Malathion)
    2. Name one antidote used in its
    poisoning Atropine
    1. Name one neuromuscular blocker
    used for this procedure?
    Succinylcholin
    2. Mention one adverse
    e effect for
    the drug usedMivacurium
    1. Identify Drug X Competitive N.M.Blocker
    2. Name a drug to reverse its action
    Neostigmine
    ACh Na

    Drug X
    ACh
    1. Name a drug used prior to this
    test.
    2. What is its duration of action?
    2
    Homatropine /
    Cyclopentolate
    3-7days/ 1 day

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