Applied Epidemiology: DR Hamid Hussain
Applied Epidemiology: DR Hamid Hussain
Applied Epidemiology: DR Hamid Hussain
Dr Hamid Hussain
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Descriptive Epidemiology is the Antecedent to Analytical Epidemiology
Descriptive Epidemiology
◦ To Describe the occurrence of disease fully,
some broad questions must be answered: Who is
affected? Where and When do the case occur? In
other words, it is necessary to specify person,
place, and time
Analytic Epidemiology
◦ Testing a hypothesis about the cause of disease
by studying how exposures relate to the disease
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THE THREE ESSENTIAL CHARACTERISTICS OF DISEASE WE LOOK
FOR IN DESCRIPTIVE EPIDEMIOLOGY ARE:
1.PERSON
2.PLACE
3.TIME
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Age, gender, ethnicity
Genetic predisposition
Concurrent disease
Risk taking behavior
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Age: Mortality and morbidity rates of almost all
conditions show some relation to this variable.
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Sex: The analysis of disease rates by sex shows that
the death rates are higher for males than females, but
morbidity rates are generally higher in females.
Ethnic group and Race: As many diseases differ
markedly in frequency, severity, or both in different
racial groups and statistics by race are helpful for
identifying health problems, therefore classification
and recording of data by ethnic group or race is
required.
Other person variables are social class, occupation,
marital status, family variables (which include family
size, birth order, maternal age, and parental
deprivation), blood type, environmental exposures,
and personality traits, etc.
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Geographic place
• presence of agents or vectors
• climate
• population density
• economic development
• nutritional practices
• medical practices
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Calendar Time
◦ Diseases in 19th & 20th century
Time since an event
◦ Hepatitis B after surgery
Physiologic cycles
◦ Changes with life, puberty etc.
Age (time since birth)
◦ Diseases of infants, adolescent, old age
Seasonality
influenza
Temporal trends
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THE THREE PHENOMENA ASSESSED IN ANALYTIC
EPIDEMIOLOGY ARE:
HOST
AGENT ENVIRONMENT
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•Host Factors
•Personal traits (age, sex,
Host
race, customs, Occupation,
marital status, )
•Behaviors
•Genetic Predisposition
•Immunologic factors
Agent Environment
•Agents
Host
•Biological (bacteria, virus)
•Physical (trauma, radiation)
•Chemical (poison, alcohol)
•Nutritional (lack, excess)
Agent Environment
Physical or biologic
or social
Agent Environment
in the population
Due to environmental changes that affect
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…are often framed under the mantle of descriptive and analytic
epidemiology
◦ 1. Descriptive epidemiology – person, place & time
Demographic distribution
Geographic distribution
Seasonal patterns etc.
Frequency of disease patterns
◦ Useful for:
Allocating resources
Planning programs
Hypotheses development
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2. Analytic epidemiology
◦ built around the analysis of the relationship
between two items
Exposures
Effects (disease)
◦ looking for determinants or possible causes of
disease
◦ useful for
Hypothesis testing
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