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    Stem Cell

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    Jesse Pinkman
    Stem cells are biological cells that can differentiate into other cell types and divide to produce more stem cells. Gene therapy is an experimental technique that uses genes to treat or prevent disease by inserting a gene into a patient's cells. There are two types of gene therapy: somatic gene therapy targets non-reproductive cells and effects are not hereditary, while germline gene therapy targets reproductive cells so effects can be inherited. Gene therapy techniques include gene augmentation therapy, which adds a functional gene, and gene inhibition therapy, which inhibits or interferes with a problematic gene. Potential advantages are a cure rather than just symptom treatment, though safety concerns remain due to its experimental nature.

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    Stem Cell

    Uploaded by

    Jesse Pinkman
    31 views16 pages
    Stem cells are biological cells that can differentiate into other cell types and divide to produce more stem cells. Gene therapy is an experimental technique that uses genes to treat or prevent disease by inserting a gene into a patient's cells. There are two types of gene therapy: somatic gene therapy targets non-reproductive cells and effects are not hereditary, while germline gene therapy targets reproductive cells so effects can be inherited. Gene therapy techniques include gene augmentation therapy, which adds a functional gene, and gene inhibition therapy, which inhibits or interferes with a problematic gene. Potential advantages are a cure rather than just symptom treatment, though safety concerns remain due to its experimental nature.

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    Stem cells are biological cells that can differentiate into other cell types and divide to produce more stem cells. Gene therapy is an experimental technique that uses genes to treat or prevent disease by inserting a gene into a patient's cells. There are two types of gene therapy: somatic gene therapy targets non-reproductive cells and effects are not hereditary, while germline gene therapy targets reproductive cells so effects can be inherited. Gene therapy techniques include gene augmentation therapy, which adds a functional gene, and gene inhibition therapy, which inhibits or interferes with a problematic gene. Potential advantages are a cure rather than just symptom treatment, though safety concerns remain due to its experimental nature.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    31 views16 pages

    Stem Cell

    Uploaded by

    Jesse Pinkman
    Stem cells are biological cells that can differentiate into other cell types and divide to produce more stem cells. Gene therapy is an experimental technique that uses genes to treat or prevent disease by inserting a gene into a patient's cells. There are two types of gene therapy: somatic gene therapy targets non-reproductive cells and effects are not hereditary, while germline gene therapy targets reproductive cells so effects can be inherited. Gene therapy techniques include gene augmentation therapy, which adds a functional gene, and gene inhibition therapy, which inhibits or interferes with a problematic gene. Potential advantages are a cure rather than just symptom treatment, though safety concerns remain due to its experimental nature.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 16

    Stem Cell

    Objectives
    To know:
     What is Stem cell
     What is Gene Therapy
     What are the two types of Gene Therapy
     What are the techniques of Gene therapy
     What are the advantages and disadvantages of Gene
    Therapy
    What is Stem Cell?
    Stem cells are biological cells that can 
    differentiate into other types of cells and can 
    divide to produce more of the same type of
    stem cells. They are found in 
    multicellular organisms.

    https://en.wikipedia.org/wiki/Stem_cell
    What is gene therapy?
    Gene therapy is an experimental technique
    that uses genes to treat or prevent disease. In
    the future, this technique may allow doctors
    to treat a disorder by inserting a gene into a
    patient’s cells instead of using drugs or
    surgery.

    https://ghr.nlm.nih.gov/primer/therapy/genetherapy
    There are two different types of gene therapy
    depending on which types of cells are treated:

     Somatic gene therapy: transfer of a section of DNA to


    any cell of the body that doesn’t produce sperm or eggs.
    Effects of gene therapy will not be passed onto the
    patient’s children.
     Germline gene therapy:transfer of a section of DNA to
    cells that produce eggs or sperm. Effects of gene therapy
    will be passed onto the patient’s children and subsequent
    generations.

    https://www.yourgenome.org/facts/what-is-gene-therapy
    Somatic gene therapy

    http://www.open.edu
    /openlearn/science-
    maths-
    technology/science/b
    iology/gene-
    therapy/content-
    section-3
    Germline gene therapy

    http://science.sciencem
    ag.org/content/348/624
    1/1325.1
    Gene therapy techniques

    Gene augmentation therapy


    Gene inhibition therapy
    Gene augmentation therapy
     This is used to treat diseases caused by a mutation that
    stops a gene from producing a functioning product, such as
    a protein?.
     This therapy adds DNA containing a functional version of
    the lost gene back into the cell.
     The new gene produces a functioning product at sufficient
    levels to replace the protein that was originally missing.
     This is only successful if the effects of the disease are
    reversible or have not resulted in lasting damage to the
    body.

    https://www.yourgenome.org/facts/what-is-gene-therapy
    Gene augmentation therapy

    https://www.yourgenome.org/facts/what-is-gene-therapy
    Gene inhibition therapy
     Suitable for the treatment of infectious diseases, cancer
    and inherited disease caused by inappropriate gene
    activity.
     The aim is to introduce a gene whose product either:
     inhibits the expression of another gene
     interferes with the activity of the product of another
    gene.
     The basis of this therapy is to eliminate the activity of a
    gene that encourages the growth of disease-related cells.

    https://www.yourgenome.org/facts/what-is-gene-therapy
    Gene inhibition therapy

    https://www.yourgenome.org/facts/what-is-gene-therapy
    Advantages of Gene Therapy
     One of the benefits of somatic gene therapy is that it can be utilized
    in a way that can possibly cure patients that are severely ill. It can
    also prevent the onset of devastating illnesses.
     Although this is experimental,  medical professionals generally use
    the best treatment methods available.  Using this process, it
    promotes the freedom of scientific inquiry and the freedom of
    knowledge.
     Gene therapy, when successful, can have a number of advantages in
    comparison to drug therapy .For example, this  therapy can provide
    a cure rather than ease the patient's symptoms.

    https://genetherapyinthefuture.weebly.com/advantages-and-disadvantages.html
    Disadvantages of Gene Therapy
     Due to the fact that this is still a new scientific breakthrough, the safety concerns
    outweigh quite a bit of the procedures. The current  understanding of gene therapy
    is based on theory rather than fact.
     There are numerous ethical concerns, as well as religious and moral concerns.
     Concerning the vector: once is is administered, there is no way for certain to tell if
    the vector will travel to the intended location. This creates even more damage to
    the genetic structure and cause more damage to the patient.
     In clinical trials already carried out the effects of the treatment have only been
    short-lived. To achieve long term results much more research is needed.

    https://genetherapyinthefuture.weebly.com/advantages-and-disadvantages.html

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