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    Effects of Some Drugs On The Eye of Rabbit: Asmaa Gamal Abdelzaher

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    pharmacology Art
    This document summarizes the effects of various drugs on the eye of rabbits. It outlines the sympathetic and parasympathetic nervous systems and their roles in controlling different parts of the eye. Acetylcholine and norepinephrine are described as neurotransmitters that act on cholinergic and adrenergic receptors in the eye to mediate various functions like accommodation, pupil size, and secretion of aqueous humor. Specific drugs that cause miosis or mydriasis are listed along with whether they affect the light reflex and corneal reflex. Sources and references are provided at the end.

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    Effects of Some Drugs On The Eye of Rabbit: Asmaa Gamal Abdelzaher

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    pharmacology Art
    27 views18 pages
    This document summarizes the effects of various drugs on the eye of rabbits. It outlines the sympathetic and parasympathetic nervous systems and their roles in controlling different parts of the eye. Acetylcholine and norepinephrine are described as neurotransmitters that act on cholinergic and adrenergic receptors in the eye to mediate various functions like accommodation, pupil size, and secretion of aqueous humor. Specific drugs that cause miosis or mydriasis are listed along with whether they affect the light reflex and corneal reflex. Sources and references are provided at the end.

    Original Title

    Eye Pharmacology

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    This document summarizes the effects of various drugs on the eye of rabbits. It outlines the sympathetic and parasympathetic nervous systems and their roles in controlling different parts of the eye. Acetylcholine and norepinephrine are described as neurotransmitters that act on cholinergic and adrenergic receptors in the eye to mediate various functions like accommodation, pupil size, and secretion of aqueous humor. Specific drugs that cause miosis or mydriasis are listed along with whether they affect the light reflex and corneal reflex. Sources and references are provided at the end.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    27 views18 pages

    Effects of Some Drugs On The Eye of Rabbit: Asmaa Gamal Abdelzaher

    Uploaded by

    pharmacology Art
    This document summarizes the effects of various drugs on the eye of rabbits. It outlines the sympathetic and parasympathetic nervous systems and their roles in controlling different parts of the eye. Acetylcholine and norepinephrine are described as neurotransmitters that act on cholinergic and adrenergic receptors in the eye to mediate various functions like accommodation, pupil size, and secretion of aqueous humor. Specific drugs that cause miosis or mydriasis are listed along with whether they affect the light reflex and corneal reflex. Sources and references are provided at the end.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 18

    Effects Of Some Drugs On

    The Eye Of Rabbit


    Asmaa Gamal Abdelzaher
    Nervous System

    Central Peripheral

    Sensory Motor

    Somatic Autonomic

    Skeletal Muscle Parasympathetic Sympathetic


    Origin:
    Sympathetic :
    Thoracolumbar T1 L3
    Parasympathetic:
    Craniosacral
    3,7,9,10 cranial nerves
    sacral S2,3,4
    Acetylcholine Norepinephrine
    Receptors
    Cholinergic Adrenergic

    Gq M1 Gq α1
    Gi M2 Gi α2
    Gq M3 Gs B1
    Ligand Nn Gs B2
    gated Na
    channel Gs B3
    Ligand Nm
    gated Na
    channel
    Accommodation M3
    Aqueous secretion B2
    Eye Receptors
    Cholinergic Adrenergic

    Muscle: M3 Muscle: α1
    Miosis Mydriasis
    Accommodation Loss of
    ↓IOP Accommodation
    B.V: V.D ↑IOP
    Glands: B.V: V.C
    Lacrimation ↓aqueous humor
    secretion
    Eye lid twitches Nm ↑aqueous humor B2
    formation
    Corneal Reflex
    Corneal Reflex
    Light Reflex
    Light Reflex
    Drugs affecting Pupil
    size

    Mydriasis Miosis
    P.S mimetic
    Light reflex
    Lost Present Eye lid twitch Present
    Absent
    (Passive mydriasis) (Active mydriasis) M&N
    M only
    P.S lytic Corneal reflex Pilocarpine Carbacol & all Indirect
    1) Atropine Present Lost Reversible Anti-
    S. mimetic Surface anesthetic Cholinesterase
    2) Hyoscine (α1 agonist): Prazocin, (Cocaine) (Physosigmine-Neostigmine-
    Neostigmine substitute)
    3) Atropine Phenylephrine
    substitute Amphetamine-Ephedrine Irreversible Anti-
    Homatropine Cholinesterase
    Eucatropine (OPC "Organo-Phosphorus
    Compound")
    Tropicamide
    Cyclopentolate
    :Sources and Reference
    Images from google web sites
    Text from Dr/ Mohsen and Dr/ Nawal
    Pharmacology Practical book volumeI

    Reference:
    Katzung and Trevor’s textbook.
    contact me: Asmaa Gamal
    Pharmacology Art page on facebook
    e-mail : aga12@fayoum.edu.eg
    phone number whatsapp : 01092559953

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