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5ajjbebtjmtff7km0lpa Signature Poli 180920055258

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Dr .

bharath rajh
Junior resident
Dept of plastic
surgery
Parotid gland – anatomy


 The parotid glands are a pair of mainly serous
salivary glands

 Located inferior and anterior to the external acoustic


meatus, between the ramus of mandible and
sternocleidomastoid muscle.

 The gland is roughly wedge-shaped



 Gland is divided into two
o
lbes

 Superficial lobe – 80%

 Deep lobe – 20 %
Parotid duct

 Also called as Stenson’s duct

 It emerges from the anterior border of the gland,


superficial to the masseter muscle, then it pierces the
buccinator muscle & opens into the oral cavity on the
inner surface of the cheek, usually opposite to the
maxillary second molar.

Parotid capsule

 Investing layer of deep fascia forms the
capsule

 Splits into

 Superficial lamina
 Deep lamina

Structures passing through
parotid gland

Artery:
External carotid enters in the posteromedial surface

Maxillary artery

Superficial temporal artery

Posterior auricular artery




Nerve supply

 Parasympathetic fibres :- Secretomotor
 Preganglionic fibres arise from the inferior
salivatory
nucleus
 Pass through glossopharyngeal nerve
 Relay in otic ganglion
 Postganglionic fibres reach the gland through
auriculotemporal nerve
 Sympathetic fibres :- Vasomotor
 Sensory nerves :- Auriculotemporal nerve
Parotid neoplasia

 Benign
 Pleomorphic adenoma
 Warthin’s tumor
 Malignant
 Mucoepidermoid
carcinoma
 Adenoid cystic carcinoma
 Acinic cell carcinoma
 Adenocarcinoma
 Squamous cell carcinoma
Pleomorphic adenoma

 It is also known as “Mixed salivary tumor”

 It is the most common benign tumor of salivary


glands – 80 %

 Characterized by neoplastic proliferation


of parenchymatous glandular cells along
with myoepithelial components

 Distribution:
 Parotid gland: 84%
 Submandibular gland: 8%
 Minor salivary glands: 6.5%
 Widely distributed including the nasal cavity,
pharynx, larynx, trachea
 Sublingual glands: 0.5%
Clinical features

 Swelling
 Painless
 Raised ear lobule
 Curtain sign positive

 Common in females (3:1)
 Common in 4th and 5th decade of life
 Smooth , firm lobulated mobile swelling
wh
ti positive curtain sign
 Ear lobule lifted
 Obliteration of retro mandibular groove
 Deep lobe tumour passes through Patey’s
stylomandibular tunnel pushing tonsil, pharynx,
uvula
 Along with dysphagia
Features of malignant change

 1.5% in 5 yrs. ; 9.5% in 15
yrs.
 Recent increase in Capsular distension
Obstruction of
zsie
saliva Nerve
 Pain infiltration Tumour
 Nodularity necrosis
 Involvement of skin, LN , Facial nerve,
masseter
 Restriction of jaw movements
Pathology

 Gross:
 Cartilages
 Cystic
spaces
 Solid
tissues
Histology

 They contain both epithelial and myoepithelial
(mesenchymal) tissues

 Even though it is capsulated, tumor may come out


as
pseudopods beyond the original extend of the tumor
Diagnosis

 Fine needle
aspiration

 Core needle
aspiration

 USG

 CT scan

 MRI scan

 USG – Hypoechoic with lobulated and distinct
borders

 CT scan – Smoothly margined or lobulated
homogeneous small spherical mass

 Small regions of calcification

 When the tumour is small, the enhancement tends


to be prominent

 MRI :
 Well-circumscribed and homogeneous
 T1: Usually of low intensity
 T2: Usually of very high intensity (especially myxoid
type)
 T1 C+ (Gd): Usually demonstrates homogeneous
enhancement
Treatment

 Surgical excision of the
tumour

 Superficial(Patey's operation)
parotidectomy
 Total parotidectomy

 Complications:
 Recurrence of 5 to 50%
 Facial nerve injury
Warthin’s tumour

 It is also called Adenolymphoma or Papillary
cystadenolymphomatosum

 It is a benign tumour occurs only in parotid, usualy


in the superficial lobe, lower pole.

 Second most common



 Usually
10 – 15 %occurs in 6th
bilateral
decade

 More common in males


41:

 Associations:
 Cigarette smoking
 Irradiation
Morphology

 Slow growing, non tender, smooth, soft, cystic,
fluctuant swelling.
 Often multi-centric and are usually small
(1-4 cm.)
 Typically heterogeneous appearance on
all modalities, often with cystic
components


Investigations

 Ultrasound :
 A well defined, ovoid, hyper echoic mass.
 In some cases anechoic internal cystic areas may
be present. They are often hyper vascular
 CT scan:
 Can be often well defined , bilateral tumor
 Classic appearance is a cystic lesion posteriorly
within h te
parotid with a focal tumour nodule
 Cystic changes appear as intralesional lower
attenuation
 No calcification


 Adenolymphoma produces a “Hot
spot“ in Technetium99-pertechnetate scan
 Diagnostic – due to high mitochondrial
content
Treatment

 Surgical excision is
curative

 Rate of recurrence is
almost nil

 No malignant change
Mucoepidermoid tumor

 Commonest type of malignant salivary tumor
in adults

 Commonest malignant tumor of parotid


in childhood

 Common in middle age (35-65 years of


age)

 Female predilection

 Parotid is the most common site of tumor

 2nd common is palate minor salivary gland

 Radiation – etiological factor

 t(11;19)(q21;p13) chromosome translocation resulting


in a MECT1-MAML2 fusion gene

 Presents as painless, slow-growing mass that is
rm
if or hard.

 Grossly – Un encapsulated mass with cystic


spaces

 Facial nerve involvement in late stages


Histology

 The tumours are composed of a
mixture of:

 Mucus secreting cells (muco- )

 Squamous cells (-epidermoid)

 Lymphoid infiltrate often also present


Grade of tumor

 Low grade:
 Well-differentiated cells with little cellular
atypia
 High proportion of mucous cells
 Prominent cyst formation
 Intermediate grade: intermediate features
 High grade:
 Poorly differentiated with cellular
pleomorphism
 High proportion of squamous cells
 Solid with few if any cysts

 USG :- well-circumscribed hypo echoic lesion, with
a partial or completely cystic appearance

 CT scan :- Low-grade tumors appear as


we-l circumscribed masses, usually with cystic
components. Calcification may be present

 High-grade tumors are poorly defined margins,


infiltrate locally and appear solid.
Treatment

 Low grade – wide local excision or superficial
parotidectomy without any adjuvant radiotherapy

 High grade requires complete or radical


parotidectomy, often with sacrifice of the facial
nerve, neck dissection (as nodal metastases are
common) and adjuvant radiotherapy
Adenoid cystic carcinoma

 It is also called as cylindromatous carcinoma

 Low grade tumor

 Wide distribution and mainly occur in relation to


the airways, salivary glands, lacrimal glands and
breast

 Tendency for perineural extension is high



 Common in females 3:1
 Occurs in 5th & 6th decade of life
 Slow growing tumor but highly malignant

 High affinity for perineural transmission


[Anterograde and retrograde]
 Maxillary and mandibular branch of
trigeminal nerve
 Facial nerve
 Reaches Gasserian trigeminal ganglion,
pterygopalantine ganglion & cavernous sinus

  Microscopy:-
Cribriform – Swiss cheese pattern
 Tubular
 Solid

 It involves periosteum and bony


medula

Treatment

 Radical parotidectomy with adjucvant
radiotherapy

 Fast neutron therapy

 Chemotherapy

 Recurrence is common
5 years survival rate is 89 %

 15 years survival rate is 40 %

 Positive margin, perineural spread, solid type cary


poor prognosis
Parotidectomy

 Indications:
 Chronic parotitis
 Salivary calculi
 Parotid abscess
 Parotid tumors
 T1,T2,T3 – Total conservative
parotidectomy
 T4 – Radical parotidectomy

  Types: Superficial parotidectomy
 Total conservative
parotidectomy
 Radical parotidectomy
 Suprafacial parotidectomy
Identification of facial nerve

 Facial nerve is 1cm deep and below the tip of inferior
portion of cartilaginous canal – conley’s point
 By nerve stimulator
 It is inferomedial to the tragal point
 Deep to digastric muscle
 Nerve is just lateral to styloid process
 Tracing branch from distal to proximal (Hamilton
bailey technique)
Indication for nerve sacrifice

 Preoperative weakness / paralysis of nerve
 Intraoperative evidence of gross invasion
 Tumors transgressing through facial nerve
o
rfm superficial to deep lobe
 Nerve stump is checked for frozen section for
negative margins, if positive, mastoidectomy
& nerve dissection is required






Complications of
parotidectomy


 Facial nerve injury
 Hemorrhage
Infection – flap necrosis is
c
ommon Salivary fistula
 Frey’s syndrome
 Sialocele
 Injury to greater auricular nerve

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