Methamphetamine
Methamphetamine
Methamphetamine
What is Methamphetamine?
Methamphetamine is a central nervous system stimulant drug that is similar in structure to amphetamine. Also known as: "speed", "ice", "meth", "crystal" and "crank"
Mode of action
Methamphetamine acts on the pleasure circuit in the brain Causes the release of nuerotransmitters such as Dopamine or NE, and blocks their breakdown causing building up of DA and NE which causes the feeling of Euphoria and pleasure.
Clinical uses
In treatment of ADHD Exogenous obisity.
Stroke Sweating Nausea, vomiting, diarrhea Long periods of sleep ("crashing" for 24-48 hours or more) Prolonged sluggishness, severe depression Weight loss, malnutrition, anorexia Itching (illusion that bugs are crawling on the skin) Welts on the skin Involuntary body movements Paranoid delusions
Physiological effects
abnormally high blood pressure rapid and irregular heart rate and rhythm seizures damage to blood vessels in the brain (stroke) accumulation of excess fluid in lungs, brain tissue and skull continuous/excessive dilation of the pupils impaired regulation of heat loss hyperpyrexia (body temperatures higher than 104) internal bleeding; damage to other organs caused by disruption of blood flow and breakdown of muscle tissue leading to kidney failure
Routes of administration
Many different routes of administration are used to take methamphetamine and it is typically used in a cycle. The drug may be snorted, smoked, orally ingested, or injected.
withdrawal
an increased apetite. Symptoms may last for days with occasional use and weeks or months with chronic use, with severity dependent on the length of time and the amount of methamphetamine used. Withdrawal symptoms may also include anxiety, irritability,headaches, agitation,akathisia,hypersomnia, (excessive sleep) vivid or lucid dreams. Deep REM sleep and suicidal ideation.
Treatment of abuse
Outpatient behavioral therapies are the standard treatment for methamphetamine abuse and dependence, although inpatient treatment is sometimes used.1 Cognitive behavior therapy and contingency management programs have been successfully used in treating cocaine addiction and may have some benefit in treating methamphetamine addiction