Aldehyde dehydrogenase 2 family member (Q2640417)

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mammalian protein found in Homo sapiens

ALDH2
epididymis secretory sperm binding protein
liver mitochondrial ALDH
ALDHI
acetaldehyde dehydrogenase 2
aldehyde dehydrogenase, mitochondrial
aldehyde dehydrogenase 2 family (mitochondrial)
ALDH class 2
ALDH-E2
nucleus-encoded mitochondrial aldehyde dehydrogenase 2

Language	Label	Description	Also known as
English	Aldehyde dehydrogenase 2 family member	mammalian protein found in Homo sapiens	ALDH2 epididymis secretory sperm binding protein liver mitochondrial ALDH ALDHI acetaldehyde dehydrogenase 2 aldehyde dehydrogenase, mitochondrial aldehyde dehydrogenase 2 family (mitochondrial) ALDH class 2 ALDH-E2 nucleus-encoded mitochondrial aldehyde dehydrogenase 2

Statements

1 reference

13 November 2019

UniProt protein ID

Aldehyde/histidinol dehydrogenase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05091

Aldehyde dehydrogenase, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05091

Aldehyde dehydrogenase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05091

Aldehyde dehydrogenase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Aldehyde dehydrogenase, glutamic acid active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Aldehyde dehydrogenase, cysteine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

electron transfer activity

determination method or standard

1 reference

8 April 2019

The mutation in the mitochondrial aldehyde dehydrogenase (ALDH2) gene responsible for alcohol-induced flushing increases turnover of the enzyme tetramers in a dominant fashion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

aldehyde dehydrogenase [NAD(P)+] activity

determination method or standard

1 reference

8 April 2019

The mutation in the mitochondrial aldehyde dehydrogenase (ALDH2) gene responsible for alcohol-induced flushing increases turnover of the enzyme tetramers in a dominant fashion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

aldehyde dehydrogenase (NAD+) activity

determination method or standard

5 references

31 October 2017

Molecular genetics of human aldehyde dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

31 October 2017

Biochemical genetic analysis of human and rodent aldehyde dehydrogenase (ALDH)

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

31 October 2017

Mitochondrial aldehyde dehydrogenase from human liver. Primary structure, differences in relation to the cytosolic enzyme, and functional correlations

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

31 October 2017

Two aldehyde dehydrogenases from human liver. Isolation via affinity chromatography and characterization of the isozymes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

determination method or standard

1 reference

8 April 2019

Crystal structure of eta-crystallin: adaptation of a class 1 aldehyde dehydrogenase for a new role in the eye lens

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

aldehyde dehydrogenase (NAD+) activity

determination method or standard

6 references

1 January 2018

Molecular genetics of human aldehyde dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

1 January 2018

Biochemical genetic analysis of human and rodent aldehyde dehydrogenase (ALDH)

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

1 January 2018

Mitochondrial aldehyde dehydrogenase from human liver. Primary structure, differences in relation to the cytosolic enzyme, and functional correlations

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

1 January 2018

Two aldehyde dehydrogenases from human liver. Isolation via affinity chromatography and characterization of the isozymes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

aldehyde dehydrogenase (NAD+) activity

determination method or standard

4 references

8 April 2019

Molecular genetics of human aldehyde dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

8 April 2019

Biochemical genetic analysis of human and rodent aldehyde dehydrogenase (ALDH)

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

extracellular exosome

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

extracellular exosome

determination method or standard

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

biological process

ethanol catabolic process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

determination method or standard

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05091&geneProductId=UniProtKB:P05091

determination method or standard

alcohol metabolic process

determination method or standard

1 reference

8 April 2019

Molecular genetics of human aldehyde dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

ethanol oxidation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

carbohydrate metabolic process

determination method or standard

1 reference

8 April 2019

The mutation in the mitochondrial aldehyde dehydrogenase (ALDH2) gene responsible for alcohol-induced flushing increases turnover of the enzyme tetramers in a dominant fashion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

electron transport chain

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05091

determination method or standard

physically interacts with

1 reference

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

Gene Atlas image

PBB GE ALDH2 201425 at fs.png
732 × 530; 11 KB

0 references

Aldehyde dehydrogenase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05091

Aldehyde dehydrogenase, glutamic acid active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05091

Aldehyde dehydrogenase, cysteine active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05091

Commons category

ALDH2

0 references

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000403349

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000403349

ENSP00000261733

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000261733

ENSP00000448179

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000448179

ENSP00000474669

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000474669

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

1 reference

UniProt protein ID

15 June 2016

language of work or name

Sitelinks

Wikipedia(10 entries)

cywiki ALDH2
dewiki Aldehyd-Dehydrogenase 2
enwiki ALDH2
eswiki ALDH2 (aldehído deshidrogenasa)
fiwiki Mitokondrioiden aldehydidehydrogenaasi
frwiki Aldéhyde déshydrogénase 2
huwiki Mitokondriális aldehid-dehidrogenáz
jawiki ALDH2
ruwiki Ацетальдегиддегидрогеназа
ukwiki ALDH2

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:ALDH2

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