Hyperforin (Q412742)

From Wikidata
Jump to navigation Jump to search
chemical compound
edit
Language Label Description Also known as
English
Hyperforin
chemical compound

    Statements

    chemical structure
    Hyperforin-skeletal.png
    963 × 1,033; 20 KB
    0 references
    mass
    536.386560144 dalton
    1 reference
    based on heuristic
    inferred from SMILES
    canonical SMILES
    CCCC(=O)C12C(=O)C(=C(C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C
    1 reference
    stated in
    PubChem
    isomeric SMILES
    CC(C)=CCC[C@]1(C)[C@@H](CC=C(C)C)C[C@@]2(CC=C(C)C)C(=O)[C@]1(C(=O)C(C)C)C(=O)C(CC=C(C)C)=C2O
    0 references
    found in taxon
    Hypericum perforatum
    55 references
    stated in
    Current St John's wort research from mode of action to clinical efficacy
    stated in
    Treatment with Hypericum perforatum L. does not trigger decreased resistance in Staphylococcus aureus against antibiotics and Hyperforin
    stated in
    High performance liquid chromatography/electrospray mass spectrometry of Hypericum perforatum extracts
    stated in
    Identification of the major constituents of Hypericum perforatum by LC/SPE/NMR and/or LC/MS.
    stated in
    Hypericum perforatum--chemical profiling and quantitative results of St. John's Wort products by an improved high-performance liquid chromatography method
    stated in
    Improved procedure for the quality control of Hypericum perforatum L.
    stated in
    Quantitative analysis of the active components and the by-products of eight dry extracts of Hypericum perforatum L. (St John's Wort).
    stated in
    Fast high-performance liquid chromatographic analysis of naphthodianthrones and phloroglucinols from Hypericum perforatum extracts
    stated in
    Comparative evaluation of St. John's wort from different Italian regions
    stated in
    Evaluation of major active components in St. John's Wort dietary supplements by high-performance liquid chromatography with photodiode array detection and electrospray mass spectrometric confirmation
    stated in
    Identification by high-performance liquid chromatography–diode array detection–mass spectrometry and quantification by high-performance liquid chromatography–UV absorbance detection of active constituents of Hypericum perforatum
    stated in
    Adhyperforin as a contributor to the effect of Hypericum perforatum L. in biochemical models of antidepressant activity
    stated in
    Step by step removal of hyperforin and hypericin: activity profile of different Hypericum preparations in behavioral models
    stated in
    The structure of hyperforin
    stated in
    The content of hypericins and phloroglucinols in Hypericum perforatum L. seedlings at early stage of development
    stated in
    Hypericum perforatum L. - chemotype without rutin from Italy
    stated in
    High performance liquid chromatographic analysis of St. John's wort with photodiode array detection.
    stated in
    Evaluation of chemical stability of St. John's wort commercial extract and some preparations
    stated in
    Development of a simple, rapid and reproducible HPLC assay for the simultaneous determination of hypericins and stabilized hyperforin in commercial St. John's wort preparations
    stated in
    Separation of hypericins and hyperforins in extracts of Hypericum perforatum L. using non-aqueous capillary electrophoresis with reversed electro-osmotic flow
    stated in
    Supercritical extraction of herbs I: Saw Palmetto, St John's Wort, Kava Root, and Echinacea
    stated in
    Clinical significance of hyperforin for the efficacy of Hypericum extracts on depressive disorders of different severities
    stated in
    Comparison of German St. John's wort products according to hyperforin and total hypericin content.
    stated in
    High-Performance Liquid Chromatography On-Line Coupled to High-Field NMR and Mass Spectrometry for Structure Elucidation of Constituents ofHypericum perforatumL.
    stated in
    Supercritical fluid extraction and high-performance liquid chromatographic determination of phloroglucinols in St. John's Wort (Hypericum perforatum L.).
    stated in
    Quantitative changes of dianthrones, hyperforin and flavonoids content in the flower ontogenesis of Hypericum perforatum
    stated in
    Phenolic compounds from Hypericum perforatum
    stated in
    Hypericum perforatum subspecies angustifolium shows a protective activity on the consequences of unavoidable stress exposure at lower doses than Hypericum perforatum perforatum.
    stated in
    Effect of acute drought stress and time of harvest on phytochemistry and dry weight of St. John's wort leaves and flowers
    stated in
    Significance of genetic and environmental aspects in the field cultivation of Hypericum perforatum
    stated in
    Quantitative phytochemical analyses of six hypericum species growing in slovenia
    stated in
    Adhyperforin: A Homologue of Hyperforin from Hypericum perforatum
    stated in
    Analysis and stability of Hyperici oleum
    stated in
    Hyperforin, possibly the major non-nitrogenous secondary metabolite of Hypericum perforatum L
    stated in
    Antidepressant activity of hypericum perforatum and hyperforin: the neglected possibility
    stated in
    Activity profiles of two hyperforin-containing hypericum extracts in behavioral models
    stated in
    Effects of a methanolic extract and a hyperforin-enriched CO2 extract of St. John's Wort (Hypericum perforatum) on intracerebral field potentials in the freely moving rat (Tele-Stereo-EEG).
    stated in
    Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers
    stated in
    Determination of Major Constituents in St. John's Wort Under Different Extraction Conditions
    stated in
    THE DEVELOPMENT AND EVALUATION OF AN HPLC-DAD METHOD FOR THE ANALYSIS OF THE PHENOLIC FRACTIONS FROM IN VIVO AND IN VITRO BIOMASS OF HYPERICUM SPECIES
    stated in
    Determining hyperforin and hypericin content in eight brands of St. John's wort.
    stated in
    A Simple and Reliable Semipreparative High-Performance Liquid Chromatography Technique for the Isolation of Marker-Grade Hyperforin from Hypericum perforatum L. Extract
    stated in
    Simultaneous Determination of the Predominant Hyperforins and Hypericins in St. John's Wort (Hypericum perforatum L.) by Liquid Chromatography
    stated in
    Determination of St. John's Wort Components in Dietary Supplements and Functional Foods by Liquid Chromatography
    stated in
    Pharmaceutical quality of hypericum extracts
    stated in
    Isolation, purity analysis and stability of hyperforin as a standard material from Hypericum perforatum L.
    stated in
    Ontogenetic Variation Regarding Hypericin and Hyperforin Levels in Four Accessions ofHypericum perforatumL.
    stated in
    Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines
    stated in
    Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.
    stated in
    Biosynthesis of hyperforin in Hypericum perforatum
    stated in
    Studies on the antioxidative activity of phloroglucinol derivatives isolated from hypericum species
    stated in
    Bisanthraquinone glycosides of Hypericum perforatum with binding inhibition to CRH-1 receptors
    stated in
    Pharmaceutical Quality of Hypericum Extracts
    stated in
    Variability in the content of the constituents of Hypericum perforatum L. and some commercial extracts
    stated in
    Investigations on the Infraspecific Variability of Hypericum perforatum L.
    Commons category
    Hyperforin
    0 references

    Identifiers

    Reaxys registry number
    6785663
    0 references
    HSDB ID
    7646
    1 reference
    stated in
    Hazardous Substances Data Bank
    HSDB ID
    7646
    publication date
    28 October 2019
    title
    HYPERFORIN (English)
    retrieved
    10 May 2021
    EC number
    601-000-9
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.112.565
    retrieved
    27 December 2018
    title
    Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, (1R,5S,6R,7S)- (English)
    quotation
    CAS no.: 11079-53-1 (English)
    ECHA Substance Infocard ID
    100.112.565
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.112.565
    retrieved
    27 December 2018
    title
    Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, (1R,5S,6R,7S)- (English)
    quotation
    CAS no.: 11079-53-1 (English)
    DrugBank ID
    DB01892
    0 references
    KNApSAcK ID
    C00034542
    0 references
    UNII
    RM741E34FP
    0 references
    NALT ID
    46555
    0 references
     
    edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q412742&oldid=2237825832"