posaconazole (Q906453)

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pharmaceutical drug

Posaconazole

Language	Label	Description	Also known as
English	posaconazole	pharmaceutical drug	Posaconazole

Statements

type of chemical entity

0 references

1 reference

27 February 2018

4-[4-[4-[4-[[(5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

0 references

1 reference

Posaconazole (English)

language of work or name

publication date

17 November 2015

chemical structure

Posaconazole Formulae.png
2,136 × 4,140; 32 KB

1 reference

imported from Wikimedia project

German Wikipedia

700.329708 dalton

1 reference

language of work or name

NCGC00185736-01 (English)

19 September 2016

chemical formula

C₃₇H₄₂F₂N₈O₄

1 reference

language of work or name

NCGC00185736-01 (English)

19 September 2016

canonical SMILES

CCC(C(C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5CC(OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F

1 reference

Posaconazole (English)

3 October 2018

isomeric SMILES

CC[C@@H]([C@H](C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@H]5C[C@](OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F

1 reference

Posaconazole (English)

3 October 2018

active ingredient in

1 reference

15 February 2018

Posaconazole Sp

1 reference

European Medicines Agency product number

EMEA/H/C/000611

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000611/human_med_000980.jsp

22 March 2017

medical condition treated

1 reference

Drug Indications Extracted from FAERS

2 October 2018

significant drug interaction

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

central respiratory depression

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

acute kidney injury

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

dasatinib monohydrate

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

muscular disease

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

muscular disease

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

central respiratory depression

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

Australian pregnancy category B3

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category C

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E*

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Posaconazole

17 May 2017

subject has role

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

trypanocidal agent

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

14-alpha demethylase inhibitor

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

2 references

NCI Thesaurus ID

C61500

1 reference

Global Substance Registration System

15 February 2018

Commons category

Posaconazole

0 references

Identifiers

InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1

1 reference

Posaconazole (English)

3 October 2018

RAGOYPUPXAKGKH-XAKZXMRKSA-N

2 references

Global Substance Registration System

15 February 2018

3 October 2018

Posaconazole (English)

CAS Registry Number

3 references

language of work or name

Posaconazole (English)

publication date

17 November 2015

Global Substance Registration System

15 February 2018

RAGOYPUPXAKGKH-XAKZXMRKSA-N

CAS Common Chemistry

10 April 2021

https://commonchemistry.cas.org/detail?cas_rn=171228-49-2

0 references

2 references

Posaconazole (English)

3 October 2018

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

mapping relation type

3 references

imported from Wikimedia project

English Wikipedia

ChEBI release 2021-03-01

matched by identifier from

International Chemical Identifier

InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

UniChem compound ID

1 reference

splash10-0udi-0112123900-47df3b00c4a4865b0d1a

0 references

DSSTox substance ID

1 reference

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol (English)

CAS no.: 171228-49-2 (English)

ECHA Substance Infocard ID

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol (English)

CAS no.: 171228-49-2 (English)

1 reference

language of work or name

Posaconazole (English)

publication date

17 November 2015

MeSH descriptor ID

1 reference

Medical Subject Headings

MeSH descriptor ID

14 March 2018

1 reference

Global Substance Registration System

15 February 2018

1 reference

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

3 references

language of work or name

POSACONAZOLE (English)

19 January 2016

Global Substance Registration System

15 February 2018

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

MedlinePlus drug identifier

route of administration

oral administration

0 references

route of administration

intravenous injection

0 references

1 reference

language of work or name

POSACONAZOLE (English)

19 January 2016

Probes And Drugs ID

0 references

1 reference

1 reference

language of work or name

Posaconazole (English)

19 January 2016

0 references

1 reference

6 April 2020

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

WikiProjectMed ID

0 references

Sitelinks

Wikipedia(17 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:Posaconazole

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