C-X-C motif chemokine ligand 10 (Q986112)

CXC chemokine

1 reference

Chemokine interleukin-8-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CXC Chemokine domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CXC chemokine, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

1 reference

8 April 2019

heparin binding

1 reference

8 April 2019

Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

CXCR3 chemokine receptor binding

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

chemokine activity

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

16 July 2018

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

protein binding

3 references

8 April 2019

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

cAMP-dependent protein kinase regulator activity

1 reference

8 April 2019

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

signaling receptor binding

1 reference

8 April 2019

Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

chemokine activity

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

chemoattractant activity

1 reference

8 April 2019

Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) alphabeta+ CD8+ single-positive T cells, [...]

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

cell component

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

8 April 2019

Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

external side of plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

extracellular space

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

intracellular anatomical structure

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

regulation of endothelial tube morphogenesis

biological process

1 reference

8 April 2019

IP-10 blocks vascular endothelial growth factor-induced endothelial cell motility and tube formation via inhibition of calpain

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

negative regulation of myoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

cellular response to heat

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

response to vitamin D

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

positive regulation of cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

T cell chemotaxis

1 reference

8 April 2019

Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

chemokine-mediated signaling pathway

1 reference

16 July 2018

Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

cell-cell signaling

1 reference

8 April 2019

Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

response to virus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

muscle organ development

1 reference

8 April 2019

Interferon-inducible protein-10 involves vascular smooth muscle cell migration, proliferation, and inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

positive regulation of monocyte chemotaxis

1 reference

8 April 2019

Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

positive regulation of release of sequestered calcium ion into cytosol

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

endothelial cell activation

IGI

1 reference

8 April 2019

IP-10 induces dissociation of newly formed blood vessels

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

positive regulation of cAMP-mediated signaling

IGI

1 reference

1 January 2018

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

regulation of T cell chemotaxis

1 reference

8 April 2019

Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

blood circulation

1 reference

8 April 2019

Interferon-inducible protein-10 involves vascular smooth muscle cell migration, proliferation, and inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

chemotaxis

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

positive regulation of leukocyte chemotaxis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

cell surface receptor signaling pathway

1 reference

8 April 2019

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

negative regulation of myoblast fusion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

defense response to virus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

regulation of cell population proliferation

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

immune response

response to auditory stimulus

3 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

negative regulation of angiogenesis

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

response to cold

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

cellular response to lipopolysaccharide

1 reference

16 July 2018

SASH1 is a scaffold molecule in endothelial TLR4 signaling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

response to gamma radiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

positive regulation of T cell migration

1 reference

8 April 2019

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

signal transduction

1 reference

8 April 2019

Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

regulation of protein kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

defense response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

1 reference

8 April 2019

inflammatory response

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

antimicrobial humoral immune response mediated by antimicrobial peptide

1 reference

21 June 2018

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778

regulation of signaling receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

cytokine-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

1 reference

8 April 2019

adenylate cyclase-activating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

response to bacterium

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

neutrophil chemotaxis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

leukocyte chemotaxis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

antimicrobial humoral immune response mediated by antimicrobial peptide

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

chemokine-mediated signaling pathway

positive chemotaxis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

regulation of apoptotic process

1 reference

8 April 2019

CXCL10 contributes to p38-mediated apoptosis in primary T lymphocytes in vitro.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778

Chemokine interleukin-8-like domain

Gene Atlas image

PBB GE CXCL10 204533 at fs.png
732 × 530; 11 KB

0 references

has part(s)

1 reference

CXC chemokine, conserved site

1 reference

CXC Chemokine domain

1 reference

D12.644.276.374.200.120.500

Identifiers

MeSH descriptor ID

D054357

subject named as

Chemokine CXCL10

0 references

MeSH tree code

0 references

D12.776.467.374.200.120.500

0 references

D23.125.300.120.500

0 references

D23.469.200.120.500

0 references

D23.529.374.200.120.500

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023