The 2021 Lucas Oil 150 was a NASCAR Camping World Truck Series race that was held on November 5, 2021. It was contested over 150 laps on the 1.00-mile (1.61 km) oval. It was the 22nd and final race of the 2021 NASCAR Camping World Truck Series season, as well as the championship race. The 4 drivers in the championship four coming into the race were Zane Smith, John Hunter Nemechek, Ben Rhodes, and Matt Crafton. Kyle Busch Motorsports driver Chandler Smith collected his second win of the season, while 3rd place finisher Ben Rhodes collected the championship.