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About: ATG8

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Autophagy-related protein 8 (Atg8) is a ubiquitin-like protein required for the formation of autophagosomal membranes. The transient conjugation of Atg8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Even though there are homologues in animals (see for example GABARAP, , GABARAPL2, MAP1LC3A, MAP1LC3B, , and ), this article mainly focuses on its role in lower eukaryotes such as Saccharomyces cerevisiae.

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  • Autophagy-related protein 8 (Atg8) is a ubiquitin-like protein required for the formation of autophagosomal membranes. The transient conjugation of Atg8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Even though there are homologues in animals (see for example GABARAP, , GABARAPL2, MAP1LC3A, MAP1LC3B, , and ), this article mainly focuses on its role in lower eukaryotes such as Saccharomyces cerevisiae. (en)
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  • 22494638 (xsd:integer)
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  • 18752 (xsd:nonNegativeInteger)
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  • 1110787540 (xsd:integer)
dbo:wikiPageWikiLink
dbp:altsymbols
  • Apg8, Aut7, Cvt5 (en)
dbp:caption
  • The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8. (en)
dbp:chromosome
  • VII (en)
dbp:colwidth
  • 35 (xsd:integer)
dbp:entrezchromosome
  • NC_001139.9 (en)
dbp:entrezgene
  • 852200 (xsd:integer)
dbp:genlocEnd
  • 163161 (xsd:integer)
dbp:genlocStart
  • 159660 (xsd:integer)
dbp:name
  • autophagy related protein 8 (en)
dbp:organism
  • S. cerevisiae strain S288c (en)
dbp:refseqmrna
  • NM_001178318 (en)
dbp:refseqprotein
  • NP_009475 (en)
dbp:symbol
  • Atg8 (en)
dbp:taxid
  • 559292 (xsd:integer)
dbp:uniprot
  • P38182 (en)
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rdfs:comment
  • Autophagy-related protein 8 (Atg8) is a ubiquitin-like protein required for the formation of autophagosomal membranes. The transient conjugation of Atg8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Even though there are homologues in animals (see for example GABARAP, , GABARAPL2, MAP1LC3A, MAP1LC3B, , and ), this article mainly focuses on its role in lower eukaryotes such as Saccharomyces cerevisiae. (en)
rdfs:label
  • ATG8 (en)
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