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About: Arimoclomol

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Arimoclomol (INN; originally codenamed BRX-345, which is a citrate salt formulation of BRX-220) is an experimental drug developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California. In 2011 the worldwide rights to arimoclomol were bought by Danish biotech company Orphazyme ApS. The European Medicines Agency (EMA) and U.S. Food & Drug Administration (FDA) granted orphan drug designation to arimoclomol as a potential treatment for Niemann-Pick type C in 2014 and 2015 respectively.

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dbo:abstract
  • Arimoclomol (INN; originally codenamed BRX-345, which is a citrate salt formulation of BRX-220) is an experimental drug developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California. In 2011 the worldwide rights to arimoclomol were bought by Danish biotech company Orphazyme ApS. The European Medicines Agency (EMA) and U.S. Food & Drug Administration (FDA) granted orphan drug designation to arimoclomol as a potential treatment for Niemann-Pick type C in 2014 and 2015 respectively. (en)
  • Arimoclomol (INN; nome in codice BRX-345, è una formulazione di sale citrato di BRX-220), esso è un farmaco sperimentale sviluppato da , una società biofarmaceutica con sede a Los Angeles, California. Il farmaco somministrato per via orale è studiato per il trattamento la sclerosi laterale amiotrofica (SLA). (it)
dbo:casNumber
  • 289893-25-0
dbo:chEMBL
  • 2107726
dbo:fdaUniiCode
  • EUT3557RT5
dbo:kegg
  • D11374
dbo:pubchem
  • 208924
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  • 4802464 (xsd:integer)
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  • 9374 (xsd:nonNegativeInteger)
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  • 1120547318 (xsd:integer)
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  • N07 (en)
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  • XX17 (en)
dbp:c
  • 14 (xsd:integer)
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  • 289893 (xsd:integer)
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  • 2107726 (xsd:integer)
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  • 21106260 (xsd:integer)
dbp:cl
  • 1 (xsd:integer)
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  • 20 (xsd:integer)
dbp:iupacName
  • N-{[-2-hydroxy-3-piperidin-1-ylpropyl]oxy}pyridine-3-carboximidoyl chloride 1-oxide (en)
dbp:kegg
  • D11374 (en)
dbp:legalStatus
  • Investigational (en)
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  • 3 (xsd:integer)
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  • 3 (xsd:integer)
dbp:pubchem
  • 208924 (xsd:integer)
dbp:routesOfAdministration
  • Oral (en)
dbp:smiles
  • O[C@H]CO\N=Cc2ccc[n+]c2 (en)
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  • 1 (xsd:integer)
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  • SGEIEGAXKLMUIZ-ZPTIMJQQSA-N (en)
dbp:unii
  • EUT3557RT5 (en)
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  • changed (en)
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  • 447557873 (xsd:integer)
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rdfs:comment
  • Arimoclomol (INN; originally codenamed BRX-345, which is a citrate salt formulation of BRX-220) is an experimental drug developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California. In 2011 the worldwide rights to arimoclomol were bought by Danish biotech company Orphazyme ApS. The European Medicines Agency (EMA) and U.S. Food & Drug Administration (FDA) granted orphan drug designation to arimoclomol as a potential treatment for Niemann-Pick type C in 2014 and 2015 respectively. (en)
  • Arimoclomol (INN; nome in codice BRX-345, è una formulazione di sale citrato di BRX-220), esso è un farmaco sperimentale sviluppato da , una società biofarmaceutica con sede a Los Angeles, California. Il farmaco somministrato per via orale è studiato per il trattamento la sclerosi laterale amiotrofica (SLA). (it)
rdfs:label
  • Arimoclomol (en)
  • Arimoclomol (it)
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