The Canisius Golden Griffins football program were the intercollegiate American football team for Canisius College located in Buffalo, New York. The team competed in the NCAA Division I-AA and were members of the Metro Atlantic Athletic Conference. The school's first football team was fielded in 1918. Canisius participated in football from 1918 to 1949, and again from 1975 to 2002, compiling an all-time record of 241–251–26. At the conclusion of the 2002 season, the Canisius football program was discontinued, along with seven other school athletic programs, as part of an effort to overhaul and streamline the school's athletic department.