About: Ced-12

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CED-12 (Cell Death Abnormality Protein-12) is a cytoplasmic, PH-domain containing adaptor protein found in Caenorhabditis elegans and Drosophila melanogaster. CED-12 is a homolog to the ELMO protein found in mammals. This protein is involved in Rac-GTPase activation, apoptotic cell phagocytosis, cell migration, and cytoskeletal rearrangements.

Property	Value
dbo:abstract	CED-12 (Cell Death Abnormality Protein-12) is a cytoplasmic, PH-domain containing adaptor protein found in Caenorhabditis elegans and Drosophila melanogaster. CED-12 is a homolog to the ELMO protein found in mammals. This protein is involved in Rac-GTPase activation, apoptotic cell phagocytosis, cell migration, and cytoskeletal rearrangements. (en)
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dbo:wikiPageRevisionID	1111862519 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Caenorhabditis_elegans dbr:Proline dbr:Cytoskeleton dbr:ELMO_(protein) dbr:Gene_knockout dbr:Phagocytosis dbr:Apoptosis dbr:CED-5 dbr:Actin dbc:Caenorhabditis_elegans_genes dbr:Drosophila_melanogaster dbr:DOCK180 dbr:RAC1 dbr:Alkane dbr:Cell_migration dbr:Focal_adhesion dbr:Rac_(GTPase) dbr:Adaptor_proteins,_vesicular_transport dbr:Ternary_complex dbr:C-terminus dbr:Guanine_nucleotide_exchange_factor dbr:Integrin dbr:Somatic_cell dbr:Extracellular_matrix dbr:Pleckstrin_homology_domain dbr:Effector_protein dbr:CED-10 dbr:CED-2 dbr:File:Apoptotic_Phagocytosis_in_C._elegans.jpg dbr:File:ELMO1_(CED-12)_and_DOCK2_(CED-5)_ternary_complex_in_apoptosis.jpg
dbp:chromosome	I (en)
dbp:entrezchromosome	NC_003279.8 (en)
dbp:entrezgene	172890 (xsd:integer)
dbp:genlocEnd	10227627 (xsd:integer)
dbp:genlocStart	10222261 (xsd:integer)
dbp:homologene	56685 (xsd:integer)
dbp:name	Cell death abnormality gene 12 (en)
dbp:organism	Caenorhabditis elegans (en)
dbp:refseqmrna	NM_060292.7 (en)
dbp:refseqprotein	NP_492693.1 (en)
dbp:symbol	CED-12 (en)
dbp:taxid	6239 (xsd:integer)
dbp:uniprot	Q8STE5 (en)
dbp:wikiPageUsesTemplate	dbt:Clear dbt:Infobox_nonhuman_protein dbt:Reflist dbt:Underline
dcterms:subject	dbc:Caenorhabditis_elegans_genes
rdfs:comment	CED-12 (Cell Death Abnormality Protein-12) is a cytoplasmic, PH-domain containing adaptor protein found in Caenorhabditis elegans and Drosophila melanogaster. CED-12 is a homolog to the ELMO protein found in mammals. This protein is involved in Rac-GTPase activation, apoptotic cell phagocytosis, cell migration, and cytoskeletal rearrangements. (en)
rdfs:label	Ced-12 (en)
owl:sameAs	wikidata:Ced-12 https://global.dbpedia.org/id/2kXHV
prov:wasDerivedFrom	wikipedia-en:Ced-12?oldid=1111862519&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Apoptotic_Phagocytosis_in_C._elegans.jpg wiki-commons:Special:FilePath/ELMO1_(CED-12)_and_DO...D-5)_ternary_complex_in_apoptosis.jpg
foaf:isPrimaryTopicOf	wikipedia-en:Ced-12
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