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- In molecular nanotechnology, chemosynthesis is any chemical synthesis where reactions occur due to random thermal motion, a class which encompasses almost all of modern synthetic chemistry. The human-authored processes of chemical engineering are accordingly represented as biomimicry of the natural phenomena above, and the entire class of non-photosynthetic chains by which complex molecules are constructed is described as chemo-. Chemosynthesis can be applied in many different areas of research, including in positional assembly of molecules. This is where molecules are assembled in certain positions in order to perform specific types of chemosynthesis using molecular building blocks. In this case synthesis is most efficiently performed through the use of molecular building blocks with a small amount of linkages. Unstrained molecules are also preferred, which is when molecules undergo minimal external stress, which leads to the molecule having a low internal energy. There are two main types of synthesis: additive and subtractive. In additive synthesis the structure starts with nothing, and then gradually molecular building blocks are added until the structure that is needed is created. In subtractive synthesis they start with a large molecule and remove building blocks one by one until the structure is achieved. This form of engineering is then contrasted with mechanosynthesis, a hypothetical process where individual molecules are mechanically manipulated to control reactions to human specification. Since photosynthesis and other natural processes create extremely complex molecules to the specifications contained in RNA and stored long-term in DNA form, advocates of molecular engineering claim that an artificial process can likewise exploit a chain of long-term storage, short-term storage, enzyme-like copying mechanisms similar to those in the cell, and ultimately produce complex molecules which need not be proteins. For instance, or carbon nanotubes could be produced by a chain of non-biological reactions that have been designed using the basic model of biology. Use of the term chemosynthesis reinforces the view that this is feasible by pointing out that several alternate means of creating complex proteins, mineral shells of mollusks and crustaceans, etc., evolved naturally, not all of them dependent on photosynthesis and a food chain from the sun via chlorophyll. Since more than one such pathway exists to creating complex molecules, even extremely specific ones such as proteins edible to fish, the likelihood of humans being able to design an entirely new one is considered (by these advocates) to be near certainty in the long run, and possible within a generation. (en)
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