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Chondroitin sulfate proteoglycans (CSPGs) are proteoglycans consisting of a protein core and a chondroitin sulfate side chain. They are known to be structural components of a variety of human tissues, including cartilage, and also play key roles in neural development and glial scar formation. They are known to be involved in certain cell processes, such as cell adhesion, cell growth, receptor binding, cell migration, and interaction with other extracellular matrix constituents. They are also known to interact with laminin, fibronectin, tenascin, and collagen. CSPGs are generally secreted from cells.

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  • Chondroitin sulfate proteoglycans (CSPGs) are proteoglycans consisting of a protein core and a chondroitin sulfate side chain. They are known to be structural components of a variety of human tissues, including cartilage, and also play key roles in neural development and glial scar formation. They are known to be involved in certain cell processes, such as cell adhesion, cell growth, receptor binding, cell migration, and interaction with other extracellular matrix constituents. They are also known to interact with laminin, fibronectin, tenascin, and collagen. CSPGs are generally secreted from cells. Importantly, CSPGs are known to inhibit axon regeneration after spinal cord injury. CSPGs contribute to glial scar formation post injury, acting as a barrier against new axons growing into the injury site. CSPGs play a crucial role in explaining why the spinal cord doesn't self-regenerate after an injury. (en)
  • 硫酸軟骨素蛋白聚糖(英語:chondroitin sulfate proteoglycan,CSPGs)又稱硫化軟骨蛋白聚醣,是硫酸软骨素與蛋白聚醣結合的產物,在腦部中調控神經系統的發育與生長,它能抑制神經纖維的再生。 (zh)
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  • 硫酸軟骨素蛋白聚糖(英語:chondroitin sulfate proteoglycan,CSPGs)又稱硫化軟骨蛋白聚醣,是硫酸软骨素與蛋白聚醣結合的產物,在腦部中調控神經系統的發育與生長,它能抑制神經纖維的再生。 (zh)
  • Chondroitin sulfate proteoglycans (CSPGs) are proteoglycans consisting of a protein core and a chondroitin sulfate side chain. They are known to be structural components of a variety of human tissues, including cartilage, and also play key roles in neural development and glial scar formation. They are known to be involved in certain cell processes, such as cell adhesion, cell growth, receptor binding, cell migration, and interaction with other extracellular matrix constituents. They are also known to interact with laminin, fibronectin, tenascin, and collagen. CSPGs are generally secreted from cells. (en)
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  • Chondroitin sulfate proteoglycan (en)
  • 硫酸軟骨素蛋白聚醣 (zh)
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