About: Cyprodime

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Cyprodime is an opioid antagonist from the morphinan family of drugs. Cyprodime is a selective opioid antagonist which blocks the μ-opioid receptor, but without affecting the δ-opioid or κ-opioid receptors. This makes it useful for scientific research as it allows the μ-opioid receptor to be selectively deactivated so that the actions of the δ and κ receptors can be studied separately, in contrast to better known opioid antagonists such as naloxone which block all three opioid receptor subtypes.

Property	Value
dbo:abstract	Cyprodime is an opioid antagonist from the morphinan family of drugs. Cyprodime is a selective opioid antagonist which blocks the μ-opioid receptor, but without affecting the δ-opioid or κ-opioid receptors. This makes it useful for scientific research as it allows the μ-opioid receptor to be selectively deactivated so that the actions of the δ and κ receptors can be studied separately, in contrast to better known opioid antagonists such as naloxone which block all three opioid receptor subtypes. (en)
dbo:casNumber	118111-54-9
dbo:chEMBL	322796
dbo:fdaUniiCode	2C6F5L8S8X
dbo:pubchem	5748293
dbo:thumbnail	wiki-commons:Special:FilePath/Cyprodime.svg?width=300
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dbo:wikiPageWikiLink	dbr:Samidorphan dbc:Ethers dbc:Ketones dbc:Phenol_ethers dbr:Morphinan dbr:Naloxone dbr:Opioid_antagonist dbc:Mu-opioid_receptor_antagonists dbr:Tianeptine dbc:Morphinans dbr:Delta_opioid_receptor dbr:Receptor_(biochemistry) dbc:Synthetic_opioids dbr:Opioid dbr:Mu_opioid_receptor dbr:Kappa_opioid_receptor dbr:Antagonist_(pharmacology)
dbp:alt	Ball-and-stick model (en) Structural formula (en)
dbp:atcPrefix	none (en)
dbp:c	22 (xsd:integer)
dbp:casNumber	118111 (xsd:integer)
dbp:chembl	322796 (xsd:integer)
dbp:chemspiderid	20133376 (xsd:integer)
dbp:h	29 (xsd:integer)
dbp:image	Cyprodime molecule ball.png (en)
dbp:iupacName	-N--4,14-dimethoxymorphinan-6-one (en)
dbp:n	1 (xsd:integer)
dbp:o	3 (xsd:integer)
dbp:pubchem	5748293 (xsd:integer)
dbp:smiles	O=C4CC[C@@]3[C@@H]2NCC5CC5 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	INUCRGMCKDQKNA-ILWGZMRPSA-N (en)
dbp:synonyms	Cyprodime (en)
dbp:unii	2 (xsd:integer)
dbp:verifiedfields	changed (en)
dbp:verifiedrevid	410884288 (xsd:integer)
dbp:watchedfields	changed (en)
dbp:width	200 (xsd:integer) 210 (xsd:integer)
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dct:subject	dbc:Ethers dbc:Ketones dbc:Phenol_ethers dbc:Mu-opioid_receptor_antagonists dbc:Morphinans dbc:Synthetic_opioids
gold:hypernym	dbr:Antagonist
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Element114840755 yago:Ketone114926294 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Quintessence114847103 yago:Relation100031921 yago:WikicatKetones dbo:Drug yago:Substance100019613 yago:WikicatEthers yago:WikicatPhenolEthers umbel-rc:DrugProduct
rdfs:comment	Cyprodime is an opioid antagonist from the morphinan family of drugs. Cyprodime is a selective opioid antagonist which blocks the μ-opioid receptor, but without affecting the δ-opioid or κ-opioid receptors. This makes it useful for scientific research as it allows the μ-opioid receptor to be selectively deactivated so that the actions of the δ and κ receptors can be studied separately, in contrast to better known opioid antagonists such as naloxone which block all three opioid receptor subtypes. (en)
rdfs:label	Cyprodime (en)
owl:sameAs	freebase:Cyprodime yago-res:Cyprodime wikidata:Cyprodime dbpedia-sh:Cyprodime dbpedia-sr:Cyprodime https://global.dbpedia.org/id/4iZZc
prov:wasDerivedFrom	wikipedia-en:Cyprodime?oldid=1107913277&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Cyprodime.svg wiki-commons:Special:FilePath/Cyprodime_molecule_ball.png
foaf:isPrimaryTopicOf	wikipedia-en:Cyprodime
is dbo:wikiPageWikiLink of	dbr:List_of_opioids dbr:C22H29NO3 dbr:Morphinan dbr:Naloxone dbr:Opioid_antagonist dbr:Opioid
is foaf:primaryTopic of	wikipedia-en:Cyprodime

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