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About: GM1

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GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue. GM1 has important physiological properties and impacts neuronal plasticity and repair mechanisms, and the release of neurotrophins in the brain. Besides its function in the physiology of the brain, GM1 acts as the site of binding for both cholera toxin and E. coli heat-labile enterotoxin (Traveller's diarrhea).

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  • GM1 (غانغليوزيد رباعي الهيكسوز لعابي أحادي (بالإنجليزية: Monosialotetrahexosylganglioside)‏) هو عضوٌ في سلسلة غانغليو من الغانغليوزيدات التي تحتوي على حمض سياليك واحد. يمتلك أيضًا خصائص فيزيولوجية هامة، كما يُؤثر على اللدونة العصبية، وآليات الإصلاح العصبي، وإطلاق المغذيات العصبية في الدماغ. بالإضافة إلى وظيفته في فيزيولوجيا الدماغ، فإنَّ GM1 يعمل موقعًا لارتباط كلٍ من ذيفان الكوليرا (إسهال المسافرين). (ar)
  • GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue. GM1 has important physiological properties and impacts neuronal plasticity and repair mechanisms, and the release of neurotrophins in the brain. Besides its function in the physiology of the brain, GM1 acts as the site of binding for both cholera toxin and E. coli heat-labile enterotoxin (Traveller's diarrhea). (en)
dbo:alternativeName
  • Monosialotetrahexosylganglioside (en)
dbo:iupacName
  • (2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-[(E,2R,3S)-3-hydroxy-2-(icosanoylamino)icos-4-enoxy]-2-(hydroxymethyl)oxan-3-yl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid (en)
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  • GM1 ganglioside.png (en)
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  • 250 (xsd:integer)
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  • -5 (xsd:integer)
dbp:othernames
  • Monosialotetrahexosylganglioside (en)
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  • 455199468 (xsd:integer)
dbp:watchedfields
  • changed (en)
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  • GM1 (غانغليوزيد رباعي الهيكسوز لعابي أحادي (بالإنجليزية: Monosialotetrahexosylganglioside)‏) هو عضوٌ في سلسلة غانغليو من الغانغليوزيدات التي تحتوي على حمض سياليك واحد. يمتلك أيضًا خصائص فيزيولوجية هامة، كما يُؤثر على اللدونة العصبية، وآليات الإصلاح العصبي، وإطلاق المغذيات العصبية في الدماغ. بالإضافة إلى وظيفته في فيزيولوجيا الدماغ، فإنَّ GM1 يعمل موقعًا لارتباط كلٍ من ذيفان الكوليرا (إسهال المسافرين). (ar)
  • GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue. GM1 has important physiological properties and impacts neuronal plasticity and repair mechanisms, and the release of neurotrophins in the brain. Besides its function in the physiology of the brain, GM1 acts as the site of binding for both cholera toxin and E. coli heat-labile enterotoxin (Traveller's diarrhea). (en)
rdfs:label
  • GM1 (ar)
  • GM1 (ca)
  • GM1 (en)
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