About: NAN-190

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

NAN-190 is a drug and research chemical widely used in scientific studies. It was previously believed to act as a selective 5-HT1A receptor antagonist, but a subsequent discovery showed that it also potently blocks the α2-adrenergic receptor. The new finding has raised significant concerns about studies using NAN-190 as a specific serotonin receptor antagonist.

Property	Value
dbo:abstract	NAN-190 is a drug and research chemical widely used in scientific studies. It was previously believed to act as a selective 5-HT1A receptor antagonist, but a subsequent discovery showed that it also potently blocks the α2-adrenergic receptor. The new finding has raised significant concerns about studies using NAN-190 as a specific serotonin receptor antagonist. (en) NAN-190 — лекарство и исследовательское вещество, широко используемое в научных исследованиях. Ранее считалось, что NAN-190 является селективным антагонистом 5-HT1A-рецепторов, однако позже было показано, что NAN-190 также сильно блокирует α2-адренорецепторы Это поднимает вопросы относительно корректности результатов исследований, использовавших NAN-190 как специфический антагонист серотониновых рецепторов. (ru)
dbo:casNumber	(hydrobromide) 102392-05-2
dbo:chEMBL	8618
dbo:fdaUniiCode	LQE19CTV54
dbo:pubchem	4431
dbo:thumbnail	wiki-commons:Special:FilePath/NAN-190.svg?width=300
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dbp:alt	Skeletal formula of NAN-190 (en) Space-filling model of the NAN-190 molecule (en)
dbp:c	23 (xsd:integer)
dbp:casNumber	102392 (xsd:integer)
dbp:chembl	8618 (xsd:integer)
dbp:chemspiderid	4278 (xsd:integer)
dbp:h	27 (xsd:integer)
dbp:image	NAN-190-3D-spacefill.png (en)
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dbp:iupharLigand	73 (xsd:integer)
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dbp:pubchem	4431 (xsd:integer)
dbp:smiles	O=C1c2ccccc2CN1CCCCN4CCNc3ccccc3OC (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	SJDOMIRMMUGQQK-UHFFFAOYSA-N (en)
dbp:unii	LQE19CTV54 (en)
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rdfs:comment	NAN-190 is a drug and research chemical widely used in scientific studies. It was previously believed to act as a selective 5-HT1A receptor antagonist, but a subsequent discovery showed that it also potently blocks the α2-adrenergic receptor. The new finding has raised significant concerns about studies using NAN-190 as a specific serotonin receptor antagonist. (en) NAN-190 — лекарство и исследовательское вещество, широко используемое в научных исследованиях. Ранее считалось, что NAN-190 является селективным антагонистом 5-HT1A-рецепторов, однако позже было показано, что NAN-190 также сильно блокирует α2-адренорецепторы Это поднимает вопросы относительно корректности результатов исследований, использовавших NAN-190 как специфический антагонист серотониновых рецепторов. (ru)
rdfs:label	NAN-190 (en) NAN-190 (ru)
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