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About: ParM

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

ParM is a prokaryotic actin homologue which provides the force to drive copies of the R1 plasmid to opposite ends of rod shaped bacteria before cytokinesis. ParM is a monomer that is encoded in the DNA of the R1 plasmid and manufactured by the host cell's ribosomes. In the cytoplasm it spontaneously polymerizes forming short strands that either bind to ParR or hydrolyze. ParR stabilizes ParM and prevents it from hydrolyzing. Once bound by ParR at both ends, monomer units continue to attach to the ends of the ParM and the resulting reaction pushes R1 plasmids to opposite ends of the cell.ParMs from different bacterial plasmids can form astonishingly diverse helical structures comprising two or four strands to maintain faithful plasmid inheritance.

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dbo:abstract
  • ParM is a prokaryotic actin homologue which provides the force to drive copies of the R1 plasmid to opposite ends of rod shaped bacteria before cytokinesis. ParM is a monomer that is encoded in the DNA of the R1 plasmid and manufactured by the host cell's ribosomes. In the cytoplasm it spontaneously polymerizes forming short strands that either bind to ParR or hydrolyze. ParR stabilizes ParM and prevents it from hydrolyzing. Once bound by ParR at both ends, monomer units continue to attach to the ends of the ParM and the resulting reaction pushes R1 plasmids to opposite ends of the cell.ParMs from different bacterial plasmids can form astonishingly diverse helical structures comprising two or four strands to maintain faithful plasmid inheritance. (en)
  • ParM è un proteina procariotica omologa all'actina (similactinica) che promuove la dei plasmidi-R1 verso i opposti dei batteri bastoncellari prima della mitosi. ParM è un monomero codificato dal DNA del plasmide R1 e tradotto in proteina dai ribosomi della . Nel citoplasma, i monomeri polimerizzano spontaneamente, formando corti filamenti che possono legare o andare incontro ad idrolisi. ParR stabilizza ParM e la protegge dall'idrolisi. (it)
  • ParM – это белок, содержащийся в прокариотических клетках, по функциям своим схожий с актином. Его роль заключается в обеспечении перемещения копий плазмид R1 к противоположным полюсам в палочковидных бактериях перед митозом.Субъединицы ParM формируют микрофиламенты, вытянутые вдоль большой оси палочковидной бактерии. (ru)
  • ParM是一种原核细胞骨架,是肌动蛋白在原核基因组中的同源物。R1质粒中携带了ParM基因,可利用杆状细菌的核糖体表达生成蛋白单体,其单体可结合到ParR上形成聚合体,聚合体能在细菌二分裂时将R1质粒固定到两端,确保在子代细菌中都保留R1质粒。 (zh)
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  • 984105465 (xsd:integer)
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dbp:cdd
  • CD10227 (en)
dbp:interpro
  • IPR042051 (en)
dbp:name
  • ParM-like (en)
dbp:pfam
  • PF06406 (en)
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  • 1 (xsd:integer)
dbp:wikiPageUsesTemplate
dcterms:subject
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rdfs:comment
  • ParM is a prokaryotic actin homologue which provides the force to drive copies of the R1 plasmid to opposite ends of rod shaped bacteria before cytokinesis. ParM is a monomer that is encoded in the DNA of the R1 plasmid and manufactured by the host cell's ribosomes. In the cytoplasm it spontaneously polymerizes forming short strands that either bind to ParR or hydrolyze. ParR stabilizes ParM and prevents it from hydrolyzing. Once bound by ParR at both ends, monomer units continue to attach to the ends of the ParM and the resulting reaction pushes R1 plasmids to opposite ends of the cell.ParMs from different bacterial plasmids can form astonishingly diverse helical structures comprising two or four strands to maintain faithful plasmid inheritance. (en)
  • ParM è un proteina procariotica omologa all'actina (similactinica) che promuove la dei plasmidi-R1 verso i opposti dei batteri bastoncellari prima della mitosi. ParM è un monomero codificato dal DNA del plasmide R1 e tradotto in proteina dai ribosomi della . Nel citoplasma, i monomeri polimerizzano spontaneamente, formando corti filamenti che possono legare o andare incontro ad idrolisi. ParR stabilizza ParM e la protegge dall'idrolisi. (it)
  • ParM – это белок, содержащийся в прокариотических клетках, по функциям своим схожий с актином. Его роль заключается в обеспечении перемещения копий плазмид R1 к противоположным полюсам в палочковидных бактериях перед митозом.Субъединицы ParM формируют микрофиламенты, вытянутые вдоль большой оси палочковидной бактерии. (ru)
  • ParM是一种原核细胞骨架,是肌动蛋白在原核基因组中的同源物。R1质粒中携带了ParM基因,可利用杆状细菌的核糖体表达生成蛋白单体,其单体可结合到ParR上形成聚合体,聚合体能在细菌二分裂时将R1质粒固定到两端,确保在子代细菌中都保留R1质粒。 (zh)
rdfs:label
  • ParM (it)
  • ParM (en)
  • ParM (ru)
  • ParM (zh)
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