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About: Quadrosilan

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Quadrosilan (INN, BAN) (brand name Cisobitan; former developmental code name KABI-1774) is a synthetic nonsteroidal estrogen that was developed in the 1970s and that is or has been used as an antigonadotropic agent in the treatment of prostate cancer. It is an organosilicon compound, and is also known as 2,6-cisdiphenylhexamethylcyclotetrasiloxane. Quadrosilan has estrogenic activity equivalent to that of estradiol, and can produce feminization and gynecomastia as side effects in male patients.

Property Value
dbo:abstract
  • Quadrosilan (INN, BAN) (brand name Cisobitan; former developmental code name KABI-1774) is a synthetic nonsteroidal estrogen that was developed in the 1970s and that is or has been used as an antigonadotropic agent in the treatment of prostate cancer. It is an organosilicon compound, and is also known as 2,6-cisdiphenylhexamethylcyclotetrasiloxane. Quadrosilan has estrogenic activity equivalent to that of estradiol, and can produce feminization and gynecomastia as side effects in male patients. (en)
dbo:alternativeName
  • Cisobitan (en)
dbo:casNumber
  • 4657-20-9
dbo:class
dbo:fdaUniiCode
  • MM48TFA73C
dbo:pubchem
  • 20774
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  • 5245 (xsd:nonNegativeInteger)
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  • 1094893425 (xsd:integer)
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  • 18 (xsd:integer)
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  • 4657 (xsd:integer)
dbp:chemspiderid
  • 19557 (xsd:integer)
dbp:class
dbp:h
  • 28 (xsd:integer)
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  • 224668 (xsd:integer)
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  • 4 (xsd:integer)
dbp:pubchem
  • 20774 (xsd:integer)
dbp:si
  • 4 (xsd:integer)
dbp:smiles
  • C[Si]1C (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • ZTQZMPQJXABFNC-UHFFFAOYSA-N (en)
dbp:synonyms
  • Quadrosilane; KABI-1774; 2,6-cisdiphenylhexa- (en)
  • methylcyclotetrasiloxane (en)
dbp:tradename
  • Cisobitan (en)
dbp:unii
  • MM48TFA73C (en)
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  • 250 (xsd:integer)
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rdfs:comment
  • Quadrosilan (INN, BAN) (brand name Cisobitan; former developmental code name KABI-1774) is a synthetic nonsteroidal estrogen that was developed in the 1970s and that is or has been used as an antigonadotropic agent in the treatment of prostate cancer. It is an organosilicon compound, and is also known as 2,6-cisdiphenylhexamethylcyclotetrasiloxane. Quadrosilan has estrogenic activity equivalent to that of estradiol, and can produce feminization and gynecomastia as side effects in male patients. (en)
rdfs:label
  • Quadrosilan (en)
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