About: SN 35210

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

SN 35210 is an arylcyclohexylamine dissociative anesthetic drug. It was derived from ketamine with the intention of producing a shorter acting agent more suitable to be used as a stand-alone drug, whereas ketamine itself generally has to be used in combination with other drugs such as midazolam to minimise the occurrence of emergence reactions due to its hallucinogenic side effects. In common with other short-acting anaesthetic drugs such as remifentanil and remimazolam, SN 35210 has had the chemical structure modified to incorporate a methyl ester group which is rapidly metabolised to a carboxylic acid, producing an inactive compound and thus rapidly terminating the effects of the drug. It was selected for development from a series of structurally related alkyl esters due to having the sh

Property	Value
dbo:abstract	SN 35210 is an arylcyclohexylamine dissociative anesthetic drug. It was derived from ketamine with the intention of producing a shorter acting agent more suitable to be used as a stand-alone drug, whereas ketamine itself generally has to be used in combination with other drugs such as midazolam to minimise the occurrence of emergence reactions due to its hallucinogenic side effects. In common with other short-acting anaesthetic drugs such as remifentanil and remimazolam, SN 35210 has had the chemical structure modified to incorporate a methyl ester group which is rapidly metabolised to a carboxylic acid, producing an inactive compound and thus rapidly terminating the effects of the drug. It was selected for development from a series of structurally related alkyl esters due to having the shortest duration of action and the most similar pharmacological profile to ketamine itself. (en)
dbo:casNumber	1450615-41-4
dbo:pubchem	71769517
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dbo:wikiPageWikiLink	dbr:Remifentanil dbr:Remimazolam dbc:NMDA_receptor_antagonists dbr:Chemical_structure dbr:Ester dbr:Anesthesia dbr:Emergence_delirium dbr:Carboxylic_acid dbc:Arylcyclohexylamines dbc:Dissociative_drugs dbr:Hallucinogen dbr:Ketamine dbr:Dissociative_drug dbr:Arylcyclohexylamine dbr:Midazolam dbr:Investigational_new_drug
dbp:atcPrefix	none (en)
dbp:c	18 (xsd:integer)
dbp:casNumber	1450615 (xsd:integer)
dbp:cl	1 (xsd:integer)
dbp:h	24 (xsd:integer)
dbp:iupacName	Methyl 4-{[1--2-oxocyclohexyl]amino}pentanoate (en)
dbp:legalStatus	dbr:Investigational_new_drug
dbp:n	1 (xsd:integer)
dbp:o	3 (xsd:integer)
dbp:pubchem	71769517 (xsd:integer)
dbp:smiles	Clc1ccccc1C2CCCCC2=O (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	QFFBIIVCZDWTKZ-UHFFFAOYSA-N (en)
dbp:width	220 (xsd:integer)
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dcterms:subject	dbc:NMDA_receptor_antagonists dbc:Arylcyclohexylamines dbc:Dissociative_drugs
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment	SN 35210 is an arylcyclohexylamine dissociative anesthetic drug. It was derived from ketamine with the intention of producing a shorter acting agent more suitable to be used as a stand-alone drug, whereas ketamine itself generally has to be used in combination with other drugs such as midazolam to minimise the occurrence of emergence reactions due to its hallucinogenic side effects. In common with other short-acting anaesthetic drugs such as remifentanil and remimazolam, SN 35210 has had the chemical structure modified to incorporate a methyl ester group which is rapidly metabolised to a carboxylic acid, producing an inactive compound and thus rapidly terminating the effects of the drug. It was selected for development from a series of structurally related alkyl esters due to having the sh (en)
rdfs:label	SN 35210 (en)
owl:sameAs	wikidata:SN 35210 https://global.dbpedia.org/id/9XxXg
prov:wasDerivedFrom	wikipedia-en:SN_35210?oldid=1100344421&ns=0
foaf:depiction	wiki-commons:Special:FilePath/SN35210_structure.png
foaf:isPrimaryTopicOf	wikipedia-en:SN_35210
is dbo:wikiPageWikiLink of	dbr:C18H24ClNO3 dbr:AM-7438 dbr:Arylcyclohexylamine dbr:Methoxpropamine
is foaf:primaryTopic of	wikipedia-en:SN_35210

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