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About: T(11:14)

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t(11;14) is a chromosomal translocation which essentially always involves the immunoglobulin heavy locus, also known as IGH in the q13 of chromosome 13, as well as cyclin D1 which is located in the q32 region of chromosome 14. Specifically, the translocation is at t(11;14)(q13;q32). The translocation is mainly found in mantle cell lymphoma, but also in B-cell prolymphocytic leukemia, in plasma cell leukemia, in splenic lymphoma with villous lymphocytes, in chronic lymphocytic leukemia, and in multiple myeloma. All these diseases involve B-lineage lymphocytes.

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  • t(11;14) is a chromosomal translocation which essentially always involves the immunoglobulin heavy locus, also known as IGH in the q13 of chromosome 13, as well as cyclin D1 which is located in the q32 region of chromosome 14. Specifically, the translocation is at t(11;14)(q13;q32). The translocation is mainly found in mantle cell lymphoma, but also in B-cell prolymphocytic leukemia, in plasma cell leukemia, in splenic lymphoma with villous lymphocytes, in chronic lymphocytic leukemia, and in multiple myeloma. All these diseases involve B-lineage lymphocytes. (en)
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  • t(11;14) is a chromosomal translocation which essentially always involves the immunoglobulin heavy locus, also known as IGH in the q13 of chromosome 13, as well as cyclin D1 which is located in the q32 region of chromosome 14. Specifically, the translocation is at t(11;14)(q13;q32). The translocation is mainly found in mantle cell lymphoma, but also in B-cell prolymphocytic leukemia, in plasma cell leukemia, in splenic lymphoma with villous lymphocytes, in chronic lymphocytic leukemia, and in multiple myeloma. All these diseases involve B-lineage lymphocytes. (en)
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  • T(11:14) (en)
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