William Douse (May 19, 1800 – February 5, 1864) was a land agent, landowner and political figure in Prince Edward Island. He represented Queens County from 1835 to 1839, then 3rd Queens from 1843 to 1847 and from 1850 to 1859 and then 4th Queens from 1859 to 1862 in the Legislative Assembly of Prince Edward Island.