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dbo:abstract
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- Mast/stem cell growth factor receptor (SCFR), aussi connue sous les noms de proto-oncogene c-Kit, tyrosine-protein kinase Kit ou CD117, est une protéine, codée chez les Humains par le gène KIT situé sur le chromosome 4 humain. De multiples variants de transcription codant différents isoformes ont été trouvés pour ce gène.KIT a été décrit en premier par le biochimiste allemand Axel Ullrich en 1987 comme l’homologue cellulaire de l’oncogène viral de sarcome félin v-kit. (fr)
- Mast/stem cell growth factor receptor (SCFR), aussi connue sous les noms de proto-oncogene c-Kit, tyrosine-protein kinase Kit ou CD117, est une protéine, codée chez les Humains par le gène KIT situé sur le chromosome 4 humain. De multiples variants de transcription codant différents isoformes ont été trouvés pour ce gène.KIT a été décrit en premier par le biochimiste allemand Axel Ullrich en 1987 comme l’homologue cellulaire de l’oncogène viral de sarcome félin v-kit. (fr)
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dbo:isPartOf
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dbo:thumbnail
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dbo:wikiPageExternalLink
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dbo:wikiPageID
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dbo:wikiPageLength
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- 30279 (xsd:nonNegativeInteger)
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dbo:wikiPageRevisionID
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dbo:wikiPageWikiLink
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prop-fr:altsymbols
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- KIT (fr)
- C-Kit; CD117; PBT; SCFR (fr)
- Kit oncogene (fr)
- KIT (fr)
- C-Kit; CD117; PBT; SCFR (fr)
- Kit oncogene (fr)
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prop-fr:année
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- 1991 (xsd:integer)
- 1992 (xsd:integer)
- 2000 (xsd:integer)
- 2001 (xsd:integer)
- 2002 (xsd:integer)
- 2003 (xsd:integer)
- 2004 (xsd:integer)
- 2005 (xsd:integer)
- 2006 (xsd:integer)
- 2007 (xsd:integer)
- 2012 (xsd:integer)
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prop-fr:auteur
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- Alai M, Mui AL, Cutler RL, et al. (fr)
- André C, Martin E, Cornu F, et al. (fr)
- Ashman LK, Cambareri AC, To LB, et al. (fr)
- Canonico B, Felici C, Papa S (fr)
- Duronio V, Welham MJ, Abraham S, et al. (fr)
- Fleischman RA (fr)
- Giebel LB, Strunk KM, Holmes SA, Spritz RA (fr)
- Gupta R, Bain BJ, Knight CL (fr)
- Kitamura Y, Hirotab S (fr)
- Larizza L, Magnani I, Beghini A (fr)
- Lasota J, Miettinen M (fr)
- Lennartsson J, Rönnstrand L (fr)
- Lev S, Yarden Y, Givol D (fr)
- Linnekin D (fr)
- Miettinen M, Lasota J (fr)
- Patnaik MM, Tefferi A, Pardanani A (fr)
- Rönnstrand L (fr)
- Sandberg AA, Bridge JA (fr)
- Spritz RA, Droetto S, Fukushima Y (fr)
- Spritz RA, Giebel LB, Holmes SA (fr)
- Valent P, Ghannadan M, Hauswirth AW, et al. (fr)
- Vandenbark GR, deCastro CM, Taylor H, et al. (fr)
- Alai M, Mui AL, Cutler RL, et al. (fr)
- André C, Martin E, Cornu F, et al. (fr)
- Ashman LK, Cambareri AC, To LB, et al. (fr)
- Canonico B, Felici C, Papa S (fr)
- Duronio V, Welham MJ, Abraham S, et al. (fr)
- Fleischman RA (fr)
- Giebel LB, Strunk KM, Holmes SA, Spritz RA (fr)
- Gupta R, Bain BJ, Knight CL (fr)
- Kitamura Y, Hirotab S (fr)
- Larizza L, Magnani I, Beghini A (fr)
- Lasota J, Miettinen M (fr)
- Lennartsson J, Rönnstrand L (fr)
- Lev S, Yarden Y, Givol D (fr)
- Linnekin D (fr)
- Miettinen M, Lasota J (fr)
- Patnaik MM, Tefferi A, Pardanani A (fr)
- Rönnstrand L (fr)
- Sandberg AA, Bridge JA (fr)
- Spritz RA, Droetto S, Fukushima Y (fr)
- Spritz RA, Giebel LB, Holmes SA (fr)
- Valent P, Ghannadan M, Hauswirth AW, et al. (fr)
- Vandenbark GR, deCastro CM, Taylor H, et al. (fr)
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prop-fr:chromosome
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prop-fr:chromosomeEtLocus
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- 4 (xsd:integer)
- 5 (xsd:integer)
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prop-fr:doi
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- 10.100200 (xsd:double)
- 10.100700 (xsd:double)
- 10.101600 (xsd:double)
- 10.105300 (xsd:double)
- 10.107300 (xsd:double)
- 10.108000 (xsd:double)
- 10.109700 (xsd:double)
- 10.115200 (xsd:double)
- 10.115900 (xsd:double)
- 10.117200 (xsd:double)
- 10.217400 (xsd:double)
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prop-fr:entrezgene
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- 3815 (xsd:integer)
- 16590 (xsd:integer)
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prop-fr:fonction
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- *protease binding,
*protein tyrosine kinase activity,
*transmembrane receptor protein tyrosine kinase activity,
*receptor signaling protein tyrosine kinase activity,
*stem cell factor receptor activity,
*protein binding,
*ATP binding,
*cytokine binding,
*protein homodimerization activity,
*metal ion binding (fr)
- *protease binding,
*protein tyrosine kinase activity,
*transmembrane receptor protein tyrosine kinase activity,
*receptor signaling protein tyrosine kinase activity,
*stem cell factor receptor activity,
*protein binding,
*ATP binding,
*cytokine binding,
*protein homodimerization activity,
*metal ion binding (fr)
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prop-fr:fr
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- TEC (fr)
- CD9 (fr)
- CRK (fr)
- BCR gene (fr)
- CD63 (fr)
- CRKL (fr)
- Cytokine receptor (fr)
- DOK1 (fr)
- GRB10 (fr)
- Grb2 (fr)
- MPDZ (fr)
- Megakaryocyte-associated tyrosine kinase (fr)
- PIK3R1 (fr)
- PTPN6 (fr)
- SOCS6 (fr)
- STAT1 (fr)
- dimère de protéine (fr)
- récepteur de cytokines (fr)
- List of genes mutated in pigmented cutaneous lesions (fr)
- TEC (fr)
- CD9 (fr)
- CRK (fr)
- BCR gene (fr)
- CD63 (fr)
- CRKL (fr)
- Cytokine receptor (fr)
- DOK1 (fr)
- GRB10 (fr)
- Grb2 (fr)
- MPDZ (fr)
- Megakaryocyte-associated tyrosine kinase (fr)
- PIK3R1 (fr)
- PTPN6 (fr)
- SOCS6 (fr)
- STAT1 (fr)
- dimère de protéine (fr)
- récepteur de cytokines (fr)
- List of genes mutated in pigmented cutaneous lesions (fr)
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prop-fr:journal
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- Blood (fr)
- J. Biol. Chem. (fr)
- Cell. Mol. Life Sci. (fr)
- Proc. Natl. Acad. Sci. U.S.A. (fr)
- Acta Haematol. (fr)
- Am. J. Hum. Genet. (fr)
- Am. J. Med. Genet. (fr)
- Appl. Immunohistochem. Mol. Morphol. (fr)
- Cancer Genet. Cytogenet. (fr)
- Curr. Cancer Drug Targ. (fr)
- Current cancer drug targets (fr)
- Int. J. Biochem. Cell Biol. (fr)
- Int. J. Hematol. (fr)
- J. Biol. Regul. Homeost. Agents (fr)
- J. Clin. Invest. (fr)
- Leuk. Lymphoma (fr)
- Oncogene (fr)
- Physiol. Rev. (fr)
- Semin Diagn Pathol (fr)
- Blood (fr)
- J. Biol. Chem. (fr)
- Cell. Mol. Life Sci. (fr)
- Proc. Natl. Acad. Sci. U.S.A. (fr)
- Acta Haematol. (fr)
- Am. J. Hum. Genet. (fr)
- Am. J. Med. Genet. (fr)
- Appl. Immunohistochem. Mol. Morphol. (fr)
- Cancer Genet. Cytogenet. (fr)
- Curr. Cancer Drug Targ. (fr)
- Current cancer drug targets (fr)
- Int. J. Biochem. Cell Biol. (fr)
- Int. J. Hematol. (fr)
- J. Biol. Regul. Homeost. Agents (fr)
- J. Clin. Invest. (fr)
- Leuk. Lymphoma (fr)
- Oncogene (fr)
- Physiol. Rev. (fr)
- Semin Diagn Pathol (fr)
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prop-fr:lang
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prop-fr:langue
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prop-fr:légende
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- Structure de la protéine KIT, PDB (fr)
- Structure de la protéine KIT, PDB (fr)
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prop-fr:nom
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- V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (fr)
- V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (fr)
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prop-fr:nomEspèce
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prop-fr:nomenclatureEc
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prop-fr:numéro
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- 1 (xsd:integer)
- 2 (xsd:integer)
- 3 (xsd:integer)
- 4 (xsd:integer)
- 5 (xsd:integer)
- 6 (xsd:integer)
- 7 (xsd:integer)
- 10 (xsd:integer)
- 11 (xsd:integer)
- 15 (xsd:integer)
- 19 (xsd:integer)
- 23 (xsd:integer)
- 25 (xsd:integer)
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prop-fr:omim
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prop-fr:pages
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- 1 (xsd:integer)
- 30 (xsd:integer)
- 65 (xsd:integer)
- 90 (xsd:integer)
- 91 (xsd:integer)
- 123 (xsd:integer)
- 205 (xsd:integer)
- 247 (xsd:integer)
- 261 (xsd:integer)
- 357 (xsd:integer)
- 492 (xsd:integer)
- 685 (xsd:integer)
- 1053 (xsd:integer)
- 1259 (xsd:integer)
- 1587 (xsd:integer)
- 1619 (xsd:integer)
- 1713 (xsd:integer)
- 2207 (xsd:integer)
- 2535 (xsd:integer)
- 2924 (xsd:integer)
- 10866 (xsd:integer)
- 18021 (xsd:integer)
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prop-fr:pmc
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- 48497 (xsd:integer)
- 295855 (xsd:integer)
- 1682440 (xsd:integer)
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prop-fr:pmid
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- 1279499 (xsd:integer)
- 1279971 (xsd:integer)
- 1370874 (xsd:integer)
- 1371879 (xsd:integer)
- 1373482 (xsd:integer)
- 1375232 (xsd:integer)
- 1376329 (xsd:integer)
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- 1381360 (xsd:integer)
- 1712644 (xsd:integer)
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- 12072198 (xsd:integer)
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- 15583854 (xsd:integer)
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- 16475976 (xsd:integer)
- 17193822 (xsd:integer)
- 17691909 (xsd:integer)
- 23073628 (xsd:integer)
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prop-fr:refseq
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- NP_000213 (fr)
- NP_001116205 (fr)
- NP_000213 (fr)
- NP_001116205 (fr)
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prop-fr:symbole
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prop-fr:texte
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- TEC (fr)
- CD9 (fr)
- BCR (fr)
- MATK (fr)
- TEC (fr)
- CD9 (fr)
- BCR (fr)
- MATK (fr)
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prop-fr:titre
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- Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells (fr)
- Cloning and structural analysis of the human c-kit gene (fr)
- Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. gastrointestinal stromal tumors (fr)
- KIT : a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation (fr)
- A recombinant ectodomain of the receptor for the stem cell factor retains ligand-induced receptor dimerization and antagonizes SCF-stimulated cellular responses (fr)
- Signal transduction-associated and cell activation-linked antigens expressed in human mast cells (fr)
- Stem cell factor receptor/c-Kit: from basic science to clinical implications. (fr)
- CD117 (fr)
- Kit as a human oncogenic tyrosine kinase (fr)
- Expression of the YB5.B8 antigen in normal human bone marrow (fr)
- Early signaling pathways activated by c-Kit in hematopoietic cells (fr)
- Organization and nucleotide sequence of the human KIT proto-oncogene (fr)
- Human piebald trait resulting from a dominant negative mutant allele of the c-kit membrane receptor gene (fr)
- p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein (fr)
- The Kasumi-1 cell line: a t-kit mutant model for acute myeloid leukemia (fr)
- KIT and PDGFRA mutations in gastrointestinal stromal tumors (fr)
- Signal transduction via the stem cell factor receptor/c-Kit (fr)
- The stem cell factor receptor/c-Kit as a drug target in cancer (fr)
- Deletion of the KIT and PDGFRA genes in a patient with piebaldism (fr)
- Cytogenetic and molecular genetic abnormalities in systemic mastocytosis (fr)
- Kit: molecule of interest for the diagnosis and treatment of mastocytosis and other neoplastic disorders (fr)
- Genomic organization of the human c-kit gene: evolution of the receptor tyrosine kinase subclass III (fr)
- Dominant negative and loss of function mutations of the c-kit proto-oncogene in human piebaldism (fr)
- Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells (fr)
- Cloning and structural analysis of the human c-kit gene (fr)
- Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. gastrointestinal stromal tumors (fr)
- KIT : a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation (fr)
- A recombinant ectodomain of the receptor for the stem cell factor retains ligand-induced receptor dimerization and antagonizes SCF-stimulated cellular responses (fr)
- Signal transduction-associated and cell activation-linked antigens expressed in human mast cells (fr)
- Stem cell factor receptor/c-Kit: from basic science to clinical implications. (fr)
- CD117 (fr)
- Kit as a human oncogenic tyrosine kinase (fr)
- Expression of the YB5.B8 antigen in normal human bone marrow (fr)
- Early signaling pathways activated by c-Kit in hematopoietic cells (fr)
- Organization and nucleotide sequence of the human KIT proto-oncogene (fr)
- Human piebald trait resulting from a dominant negative mutant allele of the c-kit membrane receptor gene (fr)
- p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein (fr)
- The Kasumi-1 cell line: a t-kit mutant model for acute myeloid leukemia (fr)
- KIT and PDGFRA mutations in gastrointestinal stromal tumors (fr)
- Signal transduction via the stem cell factor receptor/c-Kit (fr)
- The stem cell factor receptor/c-Kit as a drug target in cancer (fr)
- Deletion of the KIT and PDGFRA genes in a patient with piebaldism (fr)
- Cytogenetic and molecular genetic abnormalities in systemic mastocytosis (fr)
- Kit: molecule of interest for the diagnosis and treatment of mastocytosis and other neoplastic disorders (fr)
- Genomic organization of the human c-kit gene: evolution of the receptor tyrosine kinase subclass III (fr)
- Dominant negative and loss of function mutations of the c-kit proto-oncogene in human piebaldism (fr)
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prop-fr:trad
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- CD9 (fr)
- Cytokine receptor (fr)
- Protein dimer (fr)
- SOCS6 (fr)
- CD9 (fr)
- Cytokine receptor (fr)
- Protein dimer (fr)
- SOCS6 (fr)
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prop-fr:uniprot
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- P05532 (fr)
- P10721 (fr)
- P05532 (fr)
- P10721 (fr)
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prop-fr:volume
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- 6 (xsd:integer)
- 7 (xsd:integer)
- 13 (xsd:integer)
- 15 (xsd:integer)
- 23 (xsd:integer)
- 31 (xsd:integer)
- 44 (xsd:integer)
- 46 (xsd:integer)
- 50 (xsd:integer)
- 61 (xsd:integer)
- 75 (xsd:integer)
- 78 (xsd:integer)
- 89 (xsd:integer)
- 92 (xsd:integer)
- 107 (xsd:integer)
- 135 (xsd:integer)
- 267 (xsd:integer)
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prop-fr:wikiPageUsesTemplate
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dct:subject
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rdf:type
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rdfs:comment
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- Mast/stem cell growth factor receptor (SCFR), aussi connue sous les noms de proto-oncogene c-Kit, tyrosine-protein kinase Kit ou CD117, est une protéine, codée chez les Humains par le gène KIT situé sur le chromosome 4 humain. De multiples variants de transcription codant différents isoformes ont été trouvés pour ce gène.KIT a été décrit en premier par le biochimiste allemand Axel Ullrich en 1987 comme l’homologue cellulaire de l’oncogène viral de sarcome félin v-kit. (fr)
- Mast/stem cell growth factor receptor (SCFR), aussi connue sous les noms de proto-oncogene c-Kit, tyrosine-protein kinase Kit ou CD117, est une protéine, codée chez les Humains par le gène KIT situé sur le chromosome 4 humain. De multiples variants de transcription codant différents isoformes ont été trouvés pour ce gène.KIT a été décrit en premier par le biochimiste allemand Axel Ullrich en 1987 comme l’homologue cellulaire de l’oncogène viral de sarcome félin v-kit. (fr)
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rdfs:label
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- CD117 (fr)
- KIT (uk)
- Tyrosinkinase KIT (de)
- CD117 (fr)
- KIT (uk)
- Tyrosinkinase KIT (de)
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rdfs:seeAlso
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