CONTI, PAOLA
CONTI, PAOLA
Dipartimento di Scienze Farmaceutiche
Chemo-enzymatic flow synthesis of nature-inspired phenolic carbonates and carbamates as antimicrobial and antiradical agents
2024 F. Annunziata, S. Vicinanza, L. Mombelli, S. Donzella, G. Meroni, C. Borsari, M.L. Contente, P.A. Martino, P. Conti, A. Pinto, S. Dallavalle, L. Tamborini
Chemo-enzymatic flow synthesis of nature-inspired phenolic carbonates and carbamates as antiradical and antimicrobial agents
2024 S. Vicinanza, L. Mombelli, F. Annunziata, S. Donzella, M.L. Contente, C. Borsari, P. Conti, G. Meroni, F. Molinari, P.A.M. Martino, A. Pinto, L. Tamborini
Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents
2024 A.I. Corfu, N. Santarem, S. Luelmo, G. Mazza, A. Greco, A. Altomare, G. Ferrario, G. Nasta, O. Keminer, G. Aldini, L. Tamborini, N. Basilico, S. Parapini, S. Gul, A. Cordeiro-da-Silva, P. Conti, C. Borsari
Discovery and characterization of a new class of NAD+-independent SIRT1 activators
2024 S. DELLA TORRE, G. Dell’Omo, J. Dellavedova, L. Palazzolo, E. Scanziani, I. Eberini, A. Pinto, N. Mitro, P. Conti, A. Villa, P. Ciana
Effect of glycosylation on the affinity of the MTB protein Ag85B for specific antibodies: towards the design of a dual-acting vaccine against tuberculosis
2024 R. Bernardini, S. Tengattini, Z. Li, L. Piubelli, T. Bavaro, A.B. Modolea, M. Mattei, P. Conti, S. Marini, Y. Zhang, L. Pollegioni, C. Temporini, M. Terreni
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells
2023 A. Galbiati, S. Bova, R. Pacchiana, C. Borsari, M. Persico, A. Zana, S. Bruno, M. Donadelli, C. Fattorusso, P. Conti
Continuous biocatalysed redox reactions for the ecofriendly and improved synthesis of pharmaceutically relevant compounds
2023 F. Annunziata, M.L. Contente, R. Gandolfi, P. Conti, C. Pinna, A. Pinto, S. Dallavalle, L. Tamborini
Understanding Intrinsic Warhead Reactivity and Cysteine Druggability in Covalent Drug Discovery
2023 C. Borsari, A. Corfu, P. Conti
Role of Stereochemistry on the Biological Activity of Nature-Inspired 3-Br-Acivicin Isomers and Derivatives
2023 A. Galbiati, A. Zana, C. Borsari, M. Persico, S. Bova, O. Tkachuk, A.I. Corfu, L. Tamborini, N. Basilico, C. Fattorusso, S. Bruno, S. Parapini, P. Conti
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death
2022 R. Pacchiana, N. Mullappilly, A. Pinto, S. Bova, S. Forciniti, G. Cullia, E. Dalla Pozza, E. Bottani, I. Decimo, I. Dando, S. Bruno, P. Conti, M. Donadelli
Enzymatic continuous-flow preparation of nature-inspired phenolic esters as antiradical and antimicrobial noagents
2022 F. Annunziata, M.L. Contente, V. Anzi, S. Donzella, P. Conti, F. Molinari, P.A. Martino, G. Meroni, V.M. Sora, L. Tamborini, A. Pinto
Continuous-flow stereoselective reduction of prochiral ketones in a whole cell bioreactor with natural deep eutectic solvents
2022 F. Annunziata, A. Guaglio, P. Conti, L. Tamborini, R. Gandolfi
Design of a fully automated system for the synthesis of pharmaceutically relevant building blocks exploiting immobilized Rhodotorula rubra and new solvent systems
2021 F. Annunziata, A. Guaglio, P. Conti, R. Gandolfi, L. Tamborini
Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds
2021 A. Galbiati, A. Zana, C. Coser, L. Tamborini, N. Basilico, S. Parapini, D. Taramelli, P. Conti
Covalent inhibitors of GAPDH : From unspecific warheads to selective compounds
2020 A. Galbiati, A. Zana, P. Conti
Immobilized enzyme reactors based on nucleoside phosphorylases and 2′-deoxyribosyltransferase for the in-flow synthesis of pharmaceutically relevant nucleoside analogues
2020 F. Rinaldi, J. Fernandez-Lucas, D. de la Fuente, C. Zheng, T. Bavaro, B. Peters, G. Massolini, F. Annunziata, P. Conti, I. de la Mata, M. Terreni, E. Calleri
Use of Immobilized Amine Transaminase from Vibrio fluvialis under Flow Conditions for the Synthesis of (S)-1-(5-Fluoropyrimidin-2-yl)-ethanamine
2020 R. Semproli, G. Vaccaro, E.E. Ferrandi, M. Vanoni, T. Bavaro, G. Marrubini, F. Annunziata, P. Conti, G. Speranza, D. Monti, L. Tamborini, D. Ubiali
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign
2020 P. Linciano, G. Cullia, C. Borsari, M. Santucci, S. Ferrari, G. Witt, S. Gul, M. Kuzikov, B. Ellinger, N. Santarem, A. Cordeiro da Silva, P. Conti, M.L. Bolognesi, M. Roberti, F. Prati, F. Bartoccini, M. Retini, G. Piersanti, A. Cavalli, L. Goldoni, S.M. Bertozzi, F. Bertozzi, E. Brambilla, V. Rizzo, D. Piomelli, A. Pinto, T. Bandiera, M.P. Costi
An enzymatic flow-based preparative route to vidarabine
2020 L. Tamborini, C. Previtali, F. Annunziata, T. Bavaro, M. Terreni, E. Calleri, F. Rinaldi, A. Pinto, G. Speranza, D. Ubiali, P. Conti
An innovative synthesis of the antiviral Vidarabine through the dual use of flow chemistry and biocatalysis
2019 F. Annunziata, C. Previtali, E. Calleri, F. Rinaldi, T. Bavaro, G. Speranza, P. Conti, D. Ubiali, L. Tamborini