... Zafar Altaf Jafary, Ilyas Ahmed Faridi*, Hamid Javaid Qureshi Department of Physiology, Servi... more ... Zafar Altaf Jafary, Ilyas Ahmed Faridi*, Hamid Javaid Qureshi Department of Physiology, Services Institute of Medical Sciences, Lahore, *Faculty of Environment & Occupational Health, Institute of Public Health, Lahore. Background ...
... 1 Editorial Myocardial Regeneration in Health and Disease Mohammad Nauman Malik, Hamid Javaid... more ... 1 Editorial Myocardial Regeneration in Health and Disease Mohammad Nauman Malik, Hamid Javaid Qureshi and Tehseen Iqbal Page 2. 21 pressure or volume overload. Origin of Cells Responsible for Myocardial Renewal in Normal and Diseased Hearts ...
Journal of Ayub Medical College Abbottabad Jamc, 2010
In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopau... more In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopause and age related processes. Bone turnover increases to high levels and oestrogen deficiency may induce calcium loss by indirect effects on extra skeletal calcium homeostasis. Objective of this study was to evaluate calcium status in pre-menopausal and postmenopausal women. This cross sectional study was carried out in 34 premenopausal women and 33 postmenopausal women, in Department of Physiology, Services Institute of Medical Sciences, Lahore. Height and weight of each woman were taken to find out the body mass index (BMI). Serum calcium, parathyroid hormone and calcitonin levels of each subject were determined. Premenopausal women were obese (BMI>30 Kg/m2) while postmenopausal women were overweight (BMI>25 Kg/m2). Serum calcium levels were significantly lower in postmenopausal women than in pre-menopausal women, while serum parathyroid hormone levels were significantly higher in postmenopausal woman. Serum calcitonin level was not significantly different in the two groups. Postmenopausal women are calcium deficient and have increased bone turnover as indicated by increased serum parathyroid hormone levels.
Journal of Ayub Medical College Abbottabad Jamc, 2010
In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopau... more In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopause and age related processes. Bone turnover increases to high levels and oestrogen deficiency may induce calcium loss by indirect effects on extra skeletal calcium homeostasis. Objective of this study was to evaluate calcium status in pre-menopausal and postmenopausal women. This cross sectional study was carried out in 34 premenopausal women and 33 postmenopausal women, in Department of Physiology, Services Institute of Medical Sciences, Lahore. Height and weight of each woman were taken to find out the body mass index (BMI). Serum calcium, parathyroid hormone and calcitonin levels of each subject were determined. Premenopausal women were obese (BMI>30 Kg/m2) while postmenopausal women were overweight (BMI>25 Kg/m2). Serum calcium levels were significantly lower in postmenopausal women than in pre-menopausal women, while serum parathyroid hormone levels were significantly higher in postmenopausal woman. Serum calcitonin level was not significantly different in the two groups. Postmenopausal women are calcium deficient and have increased bone turnover as indicated by increased serum parathyroid hormone levels.
Journal of Ayub Medical College, Abbottabad : JAMC
Nigella sativa or "Kalonji" is a naturally occurring plant in Pakistan and other countr... more Nigella sativa or "Kalonji" is a naturally occurring plant in Pakistan and other countries which possesses a wide range of medicinal properties, the anti-inflammatory property being one of these. Diclofenac sodium is a commonly used anti-inflammatory drug. The purpose of this study was to compare the anti-inflammatory effect of ethanolic extract of Nigella sativa seeds with that of diclofenac sodium in albino rats. This laboratory randomized controlled trial (RCT) was conducted in the Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore. The study was carried out on 90 male albino rats. Five percent formalin in a dose of 50 µl was injected into sub-plantar surface of right hind paw of each rat to produce inflammation. The rats were randomly divided into three groups of thirty each. Group A was given normal saline (control); group B was given Nigella sativa seed extract; and group C received diclofenac sodium, as a reference drug. Increase in paw dia...
Journal of Ayub Medical College, Abbottabad : JAMC
Nigella sativa or "Kalonji" is a naturally occurring plant in Pakistan and other countr... more Nigella sativa or "Kalonji" is a naturally occurring plant in Pakistan and other countries which possesses a wide range of medicinal properties, the anti-inflammatory property being one of these. Diclofenac sodium is a commonly used anti-inflammatory drug. The purpose of this study was to compare the anti-inflammatory effect of ethanolic extract of Nigella sativa seeds with that of diclofenac sodium in albino rats. This laboratory randomized controlled trial (RCT) was conducted in the Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore. The study was carried out on 90 male albino rats. Five percent formalin in a dose of 50 µl was injected into sub-plantar surface of right hind paw of each rat to produce inflammation. The rats were randomly divided into three groups of thirty each. Group A was given normal saline (control); group B was given Nigella sativa seed extract; and group C received diclofenac sodium, as a reference drug. Increase in paw dia...
Journal of the College of Physicians and Surgeons Pakistan Jcpsp, Jul 1, 2010
OBJECTIVE: To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on expe... more OBJECTIVE: To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on experimentally-induced pain in albino mice.STUDY DESIGN: Randomized controlled trial (RCT).PLACE AND DURATION OF STUDY: Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore, from May to September, 2009.METHODOLOGY: The study was carried out in 90 male albino mice using acetic acid induced writhing test as a chemical model of nociception. The mice were divided in three groups of 30 each. Group A was given normal saline (control); group B was given Nigella sativa seed extract in a dose of 50 mg/kg; and group C received diclofenac sodium, as a reference drug. Number of writhings in treated and control groups were compared.RESULTS: The ethanolic extract of Nigella sativa seeds given intraperitoneally caused significant (p < 0.05) analgesic effect on nociceptive response initiated by 0.6% acetic acid; although this analgesic effect was less than that produced by diclofenac sodium.CONCLUSION: Ethanolic extract of Nigella sativa possessed significant analgesic effect in mice.
Journal of the College of Physicians and Surgeons Pakistan Jcpsp, Jul 1, 2010
OBJECTIVE: To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on expe... more OBJECTIVE: To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on experimentally-induced pain in albino mice.STUDY DESIGN: Randomized controlled trial (RCT).PLACE AND DURATION OF STUDY: Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore, from May to September, 2009.METHODOLOGY: The study was carried out in 90 male albino mice using acetic acid induced writhing test as a chemical model of nociception. The mice were divided in three groups of 30 each. Group A was given normal saline (control); group B was given Nigella sativa seed extract in a dose of 50 mg/kg; and group C received diclofenac sodium, as a reference drug. Number of writhings in treated and control groups were compared.RESULTS: The ethanolic extract of Nigella sativa seeds given intraperitoneally caused significant (p < 0.05) analgesic effect on nociceptive response initiated by 0.6% acetic acid; although this analgesic effect was less than that produced by diclofenac sodium.CONCLUSION: Ethanolic extract of Nigella sativa possessed significant analgesic effect in mice.
INTRODUCTION Fertility is defined as the capacity to conceive and produce offspring. Infertility ... more INTRODUCTION Fertility is defined as the capacity to conceive and produce offspring. Infertility is the state of a diminished capacity to conceive and bear offspring. The current clinical definition of infertility is the inability to conceive after 12 months of frequent coitus.1,2 Male infertility ...
INTRODUCTION Fertility is defined as the capacity to conceive and produce offspring. Infertility ... more INTRODUCTION Fertility is defined as the capacity to conceive and produce offspring. Infertility is the state of a diminished capacity to conceive and bear offspring. The current clinical definition of infertility is the inability to conceive after 12 months of frequent coitus.1,2 Male infertility ...
... Zafar Altaf Jafary, Ilyas Ahmed Faridi*, Hamid Javaid Qureshi Department of Physiology, Servi... more ... Zafar Altaf Jafary, Ilyas Ahmed Faridi*, Hamid Javaid Qureshi Department of Physiology, Services Institute of Medical Sciences, Lahore, *Faculty of Environment &amp; Occupational Health, Institute of Public Health, Lahore. Background ...
... 1 Editorial Myocardial Regeneration in Health and Disease Mohammad Nauman Malik, Hamid Javaid... more ... 1 Editorial Myocardial Regeneration in Health and Disease Mohammad Nauman Malik, Hamid Javaid Qureshi and Tehseen Iqbal Page 2. 21 pressure or volume overload. Origin of Cells Responsible for Myocardial Renewal in Normal and Diseased Hearts ...
Journal of Ayub Medical College Abbottabad Jamc, 2010
In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopau... more In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopause and age related processes. Bone turnover increases to high levels and oestrogen deficiency may induce calcium loss by indirect effects on extra skeletal calcium homeostasis. Objective of this study was to evaluate calcium status in pre-menopausal and postmenopausal women. This cross sectional study was carried out in 34 premenopausal women and 33 postmenopausal women, in Department of Physiology, Services Institute of Medical Sciences, Lahore. Height and weight of each woman were taken to find out the body mass index (BMI). Serum calcium, parathyroid hormone and calcitonin levels of each subject were determined. Premenopausal women were obese (BMI&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;30 Kg/m2) while postmenopausal women were overweight (BMI&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;25 Kg/m2). Serum calcium levels were significantly lower in postmenopausal women than in pre-menopausal women, while serum parathyroid hormone levels were significantly higher in postmenopausal woman. Serum calcitonin level was not significantly different in the two groups. Postmenopausal women are calcium deficient and have increased bone turnover as indicated by increased serum parathyroid hormone levels.
Journal of Ayub Medical College Abbottabad Jamc, 2010
In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopau... more In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopause and age related processes. Bone turnover increases to high levels and oestrogen deficiency may induce calcium loss by indirect effects on extra skeletal calcium homeostasis. Objective of this study was to evaluate calcium status in pre-menopausal and postmenopausal women. This cross sectional study was carried out in 34 premenopausal women and 33 postmenopausal women, in Department of Physiology, Services Institute of Medical Sciences, Lahore. Height and weight of each woman were taken to find out the body mass index (BMI). Serum calcium, parathyroid hormone and calcitonin levels of each subject were determined. Premenopausal women were obese (BMI&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;30 Kg/m2) while postmenopausal women were overweight (BMI&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;25 Kg/m2). Serum calcium levels were significantly lower in postmenopausal women than in pre-menopausal women, while serum parathyroid hormone levels were significantly higher in postmenopausal woman. Serum calcitonin level was not significantly different in the two groups. Postmenopausal women are calcium deficient and have increased bone turnover as indicated by increased serum parathyroid hormone levels.
Journal of Ayub Medical College, Abbottabad : JAMC
Nigella sativa or "Kalonji" is a naturally occurring plant in Pakistan and other countr... more Nigella sativa or "Kalonji" is a naturally occurring plant in Pakistan and other countries which possesses a wide range of medicinal properties, the anti-inflammatory property being one of these. Diclofenac sodium is a commonly used anti-inflammatory drug. The purpose of this study was to compare the anti-inflammatory effect of ethanolic extract of Nigella sativa seeds with that of diclofenac sodium in albino rats. This laboratory randomized controlled trial (RCT) was conducted in the Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore. The study was carried out on 90 male albino rats. Five percent formalin in a dose of 50 µl was injected into sub-plantar surface of right hind paw of each rat to produce inflammation. The rats were randomly divided into three groups of thirty each. Group A was given normal saline (control); group B was given Nigella sativa seed extract; and group C received diclofenac sodium, as a reference drug. Increase in paw dia...
Journal of Ayub Medical College, Abbottabad : JAMC
Nigella sativa or "Kalonji" is a naturally occurring plant in Pakistan and other countr... more Nigella sativa or "Kalonji" is a naturally occurring plant in Pakistan and other countries which possesses a wide range of medicinal properties, the anti-inflammatory property being one of these. Diclofenac sodium is a commonly used anti-inflammatory drug. The purpose of this study was to compare the anti-inflammatory effect of ethanolic extract of Nigella sativa seeds with that of diclofenac sodium in albino rats. This laboratory randomized controlled trial (RCT) was conducted in the Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore. The study was carried out on 90 male albino rats. Five percent formalin in a dose of 50 µl was injected into sub-plantar surface of right hind paw of each rat to produce inflammation. The rats were randomly divided into three groups of thirty each. Group A was given normal saline (control); group B was given Nigella sativa seed extract; and group C received diclofenac sodium, as a reference drug. Increase in paw dia...
Journal of the College of Physicians and Surgeons Pakistan Jcpsp, Jul 1, 2010
OBJECTIVE: To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on expe... more OBJECTIVE: To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on experimentally-induced pain in albino mice.STUDY DESIGN: Randomized controlled trial (RCT).PLACE AND DURATION OF STUDY: Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore, from May to September, 2009.METHODOLOGY: The study was carried out in 90 male albino mice using acetic acid induced writhing test as a chemical model of nociception. The mice were divided in three groups of 30 each. Group A was given normal saline (control); group B was given Nigella sativa seed extract in a dose of 50 mg/kg; and group C received diclofenac sodium, as a reference drug. Number of writhings in treated and control groups were compared.RESULTS: The ethanolic extract of Nigella sativa seeds given intraperitoneally caused significant (p < 0.05) analgesic effect on nociceptive response initiated by 0.6% acetic acid; although this analgesic effect was less than that produced by diclofenac sodium.CONCLUSION: Ethanolic extract of Nigella sativa possessed significant analgesic effect in mice.
Journal of the College of Physicians and Surgeons Pakistan Jcpsp, Jul 1, 2010
OBJECTIVE: To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on expe... more OBJECTIVE: To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on experimentally-induced pain in albino mice.STUDY DESIGN: Randomized controlled trial (RCT).PLACE AND DURATION OF STUDY: Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore, from May to September, 2009.METHODOLOGY: The study was carried out in 90 male albino mice using acetic acid induced writhing test as a chemical model of nociception. The mice were divided in three groups of 30 each. Group A was given normal saline (control); group B was given Nigella sativa seed extract in a dose of 50 mg/kg; and group C received diclofenac sodium, as a reference drug. Number of writhings in treated and control groups were compared.RESULTS: The ethanolic extract of Nigella sativa seeds given intraperitoneally caused significant (p < 0.05) analgesic effect on nociceptive response initiated by 0.6% acetic acid; although this analgesic effect was less than that produced by diclofenac sodium.CONCLUSION: Ethanolic extract of Nigella sativa possessed significant analgesic effect in mice.
INTRODUCTION Fertility is defined as the capacity to conceive and produce offspring. Infertility ... more INTRODUCTION Fertility is defined as the capacity to conceive and produce offspring. Infertility is the state of a diminished capacity to conceive and bear offspring. The current clinical definition of infertility is the inability to conceive after 12 months of frequent coitus.1,2 Male infertility ...
INTRODUCTION Fertility is defined as the capacity to conceive and produce offspring. Infertility ... more INTRODUCTION Fertility is defined as the capacity to conceive and produce offspring. Infertility is the state of a diminished capacity to conceive and bear offspring. The current clinical definition of infertility is the inability to conceive after 12 months of frequent coitus.1,2 Male infertility ...
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