In recent years, natural bioresources are being viewed as a source of potential radiation counter... more In recent years, natural bioresources are being viewed as a source of potential radiation countermeasure agents. Podophyllum hexandrum is an important medicinal plant species of the North Himalayan region that finds diverse applications in the traditional as well as modern systems of medicine. The plant has survived and evolved in harsh environments of the high altitude over several millions of years and synthesizes a number of secondary metabolites, mainly aryltetralin lignans, several of which are useful in view of their bioactive nature. The anticancer drugs viz., etoposide and teniposide are widely employed as a part of the chemotherapeutic regimen, are derived from the plant. Podophyllum has been used in the clinic for a variety of other medical purposes too. The first report on the radioprotective efficacy of Podophyllum emanated from our group. This article discusses the immense potential of the plant being used as a radioprotector during planned and unplanned radiation exposures for alleviating radiation-mediated damage. The promise of this plant finding application as a multipurpose, multiscenario radiation countermeasure agent in coming years is high and hence the need to intensify research on this important plant, which has almost reached a state of extinction. In India, several such propositions are discussed in the chapter.
In recent years, natural bioresources are being viewed as a source of potential radiation counter... more In recent years, natural bioresources are being viewed as a source of potential radiation countermeasure agents. Podophyllum hexandrum is an important medicinal plant species of the North Himalayan region that finds diverse applications in the traditional as well as modern systems of medicine. The plant has survived and evolved in harsh environments of the high altitude over several millions of years and synthesizes a number of secondary metabolites, mainly aryltetralin lignans, several of which are useful in view of their bioactive nature. The anticancer drugs viz., etoposide and teniposide are widely employed as a part of the chemotherapeutic regimen, are derived from the plant. Podophyllum has been used in the clinic for a variety of other medical purposes too. The first report on the radioprotective efficacy of Podophyllum emanated from our group. This article discusses the immense potential of the plant being used as a radioprotector during planned and unplanned radiation exposures for alleviating radiation-mediated damage. The promise of this plant finding application as a multipurpose, multiscenario radiation countermeasure agent in coming years is high and hence the need to intensify research on this important plant, which has almost reached a state of extinction. In India, several such propositions are discussed in the chapter.
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applications in the traditional as well as modern systems of medicine. The plant has survived and evolved in harsh environments of the high altitude over several millions of years and synthesizes a number of secondary metabolites, mainly aryltetralin lignans, several of which are useful in view of their bioactive nature. The anticancer drugs viz., etoposide and teniposide are widely employed as a part of the chemotherapeutic regimen, are derived from the plant. Podophyllum has been used in the clinic for a variety of other medical purposes too. The first report on the radioprotective efficacy of Podophyllum emanated from our group. This article discusses the immense potential of the plant being used as a radioprotector during planned and unplanned radiation exposures for alleviating radiation-mediated damage. The promise of this plant finding application as a multipurpose, multiscenario radiation countermeasure agent in coming years is high and hence the need to intensify research on this important plant, which has almost reached a state of extinction. In India, several such propositions are discussed in the chapter.
applications in the traditional as well as modern systems of medicine. The plant has survived and evolved in harsh environments of the high altitude over several millions of years and synthesizes a number of secondary metabolites, mainly aryltetralin lignans, several of which are useful in view of their bioactive nature. The anticancer drugs viz., etoposide and teniposide are widely employed as a part of the chemotherapeutic regimen, are derived from the plant. Podophyllum has been used in the clinic for a variety of other medical purposes too. The first report on the radioprotective efficacy of Podophyllum emanated from our group. This article discusses the immense potential of the plant being used as a radioprotector during planned and unplanned radiation exposures for alleviating radiation-mediated damage. The promise of this plant finding application as a multipurpose, multiscenario radiation countermeasure agent in coming years is high and hence the need to intensify research on this important plant, which has almost reached a state of extinction. In India, several such propositions are discussed in the chapter.