Malaria is the most common cause of ill health and death in Africa and remains a major factor limiting economic growth and development on the continent. It is a significant global public health challenge with 216 million cases and... more
Malaria is the most common cause of ill health and death
in Africa and remains a major factor limiting economic
growth and development on the continent. It is a significant
global public health challenge with 216 million cases and
655,000 deaths estimated in 2010, 86% of which were
in infants below the age of 5 years living mostly in the African
region .
From a historical perspective, man and Plasmodium falciparum
have been co-existing since the onset of the practice of
agriculture about 10, 000 to 20, 000 years ago. By domesticating
plants and animals, man became exposed to one of the major
vectors of malaria, the Anopheles gambiae sl complex. The
biological interaction between man and the malaria parasite may
have resulted in selective pressure exerted by the parasite on the
human genome such that some persons in malaria infected areas
now demonstrate selective protective advantages against severe
and lethal strains of malaria
Infection is a common cause of morbidity and mortality after liver transplantation, which are often caused by Gram negative bacteria and the most frequently occurring infectious complications after liver transplantation (LT). The aim of... more
Infection is a common cause of morbidity and mortality after liver transplantation, which are often caused by Gram negative bacteria and the most frequently occurring infectious complications after liver transplantation (LT). The aim of this study was to investigate, incidence, pathogenic spectrum, and risk factors for bacteria due to multidrug resistant (MDR) Gram-negative bacteria, and its impact on mortality after LT. In total, 150 consecutive patients who underwent liver transplantation between January 2012 and March 2013, 115 isolates of bacteria and 10 isolates fungal from 80 patients. MicroScan® microbiology and API20 were used to identify the all isolates. Bacterial infections represented the most frequent event (92.0%) and fungal infections (8.0%). The presumed sources of infection were the Urine (41 events, 51%), followed by the bail drain (14 events, 17.5%). Infections of the sputum, ascetic fluid, and blood site accounted for 13.8, 5.0 and 6.3%, respectively. Antibiotics...
