The clinical and bacteriological efficacy of norfloxacin and co-trimoxazole was compared in patie... more The clinical and bacteriological efficacy of norfloxacin and co-trimoxazole was compared in patients with symptomatic upper urinary tract infections (UTI). Norfloxacin 400 mg or cotrimoxazole (160 mg of trimethoprim plus 800 mg of sulphamethoxazole) were given orally b.i.d. for seven days to 94 Thai patients. Clinical and bacteriological assessments were performed before and at 5, 14 and 21 days after start of treatment. Bacteriological outcome could be evaluated in 69 patients, 35 randomized to norfloxacin and 34 to co-trimoxazole. The bacteriological cure rate assessed four to seven days after treatment was significantly higher in the norfloxacin than in the co-trimoxazole group (94.3% vs. 73.5%; p less than 0.05). Few patients in each group reported mild and transient adverse effects. We conclude that norfloxacin was well tolerated and more effective than co-trimoxazole in the treatment of upper UTI.
Seventeen clinical isolates of Streptococcus pneumoniae showing reduced susceptibility to ciprofl... more Seventeen clinical isolates of Streptococcus pneumoniae showing reduced susceptibility to ciprofloxacin (MIC >/= 4 micro g/ml) collected from eight different Asian countries were analyzed by antimicrobial susceptibility, serotyping, pulsed-field gel electrophoresis (PFGE), and DNA sequencing of the quinolone resistance-determining regions (QRDRs) in gyrA, gyrB, parC, and parE. All isolates but one showed more than one amino acid alteration in QRDRs of four responsible genes. Ile460 --> Val in parE was the most common mutation. Data suggest that Lys137 --> Asn in parC may be a primary step in the development of high-level and multiple FQ resistance. An additional mutation of Ser81 --> Phe in gyrA resulted in high-level resistance to ciprofloxacin, levofloxacin, and gatifloxacin, whereas Ser79 --> Phe in parC may exert an important role in the development of moxifloxacin resistance. Two novel amino acid changes in gyrB, Ala390…
Background: Unnecessary use of antibiotics can be a problem in the treatment of hordeolum since t... more Background: Unnecessary use of antibiotics can be a problem in the treatment of hordeolum since the providers prescriptions, pathogens and their susceptibilies are peculiar to local situations. Objectives: We identified current pathogenic organisms in hordeolum and its susceptibilities to antimicrobial agents in topical eye medications in Thai patients. Methods: Seventy-nine patients from the King Chulalongkorn Memorial Hospital who never received any treatment for hordeolum participated in the study. Pus specimens were collected from incision and curettage. The bacteria was stained by Gram stain and grown on aerobic and anaerobic culture agars. If there was bacterial growth, drug susceptibility test was conducted utilizing Ciprofloxacin, Fusidic acid, Oxytetracycline, Polymyxin, Neomycin, and Chloramphenicol. Results: Bacterial growth was detected in 54 isolates from 50 patients (63.3%). These isolates were identified to be Staphylococcus epidermidis (19 isolates, 35.2%), Proprioni...
bial Agents publishes original research articles, case reports and article reviews on various asp... more bial Agents publishes original research articles, case reports and article reviews on various aspects of infectious diseases and antimicrobial agents. The contributions submitted to this journal should not be published else where in whole or in part, without the Editor’s permission. Accepted contributions become the copyright of Journal. Manuscripts should be accompanied by a covering letter from the author who is responsible for correspon-dence regarding the manuscript. The covering letter should contain a statement that the manuscript has been approved by all authors. A manuscript, tables and illustrations should be sent in duplicate together with a
Performance of an immunochromatography kit (IC kit) for detection of the white spot virus in cult... more Performance of an immunochromatography kit (IC kit) for detection of the white spot virus in cultured shrimp was evaluated. The IC kit’s virus detection rate was similar to that of the one-step PCR method, but lower than that of the two-step PCR method. The antibody included in the IC kit recognized the white spot virus (WSV) envelope protein VP28, and the assay had a detection limit of 9.9×10 viral DNA copies/μl. Compared to detection based on gross and histopathological examination, this assay could detect virus even from shrimps without apparent disease signs and also few virus positive cells in the stomach and gills. When infected cultured shrimp from various countries and several other infected crustaceans were tested using the IC kit as well as onestep PCR, the IC kit was proven as a more rapid diagnostic tool.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2008
BACKGROUND AND PURPOSE Shigellosis is a major health problem in developing countries, causing 91 ... more BACKGROUND AND PURPOSE Shigellosis is a major health problem in developing countries, causing 91 million episodes and 414,000 deaths in Asia annually. Because of increasing trends towards drug resistance, this study was undertaken to monitor local resistance patterns of Shigella isolates from 8 Asian countries. METHODS Ninety eight Shigella isolates collected from 8 centers in 8 Asian countries from July 2001 to July 2004 were analyzed in terms of serogroup distribution and antimicrobial susceptibility. RESULTS The most common serogroup of Shigella isolates was Shigella flexneri (49/98, 50%), followed by Shigella sonnei (44/98, 45%). The highest resistance rate was found for trimethoprim-sulfamethoxazole (81%), followed by tetracycline (74%) and ampicillin (53%). Overall, 76 Shigella isolates (78%) were multidrug-resistant strains; S. flexneri had a higher multidrug resistance rate than S. sonnei (74% vs 23%). Increasing ciprofloxacin and ceftriaxone resistance was observed; approxi...
OBJECTIVE To study the profiles and antimicrobial susceptibility pattern of isolated bacteria fro... more OBJECTIVE To study the profiles and antimicrobial susceptibility pattern of isolated bacteria from visual threatening ocular infection. MATERIAL AND METHOD This is a retrospective review of all microbiological culture reports from visual threatening ocular infection patients admitted at King Chulalongkorn Memorial Hospital from 2005 to 2009. The culture reports with antimicrobial susceptibility pattern were analyzed and correlated with clinical presentation. RESULTS There were 682 specimens from 282 patients (286 eyes). Three most common diagnoses were corneal ulcer, endophthalmitis and scleritis, which yielded positive culture of 31.1% (38/122 eyes), 24.2% (25/103 eyes), and 55.6% (5/9 eyes), respectively. Overall, positive cultures were demonstrated from 77 eyes (27%). Pseudomonas aeruginosa was the most common causative pathogens of corneal ulcer and scleritis, while Enterococcus faecalis was the most common pathogens of endophthalmitis. All isolated Pseudomonas spp. were suscept...
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015
To study the profiles and antimicrobial susceptibility pattern of isolated bacteria from visual t... more To study the profiles and antimicrobial susceptibility pattern of isolated bacteria from visual threatening ocular infection. This is a retrospective review of all microbiological culture reports from visual threatening ocular infection patients admitted at King Chulalongkorn Memorial Hospital from 2005 to 2009. The culture reports with antimicrobial susceptibility pattern were analyzed and correlated with clinical presentation. There were 682 specimens from 282 patients (286 eyes). Three most common diagnoses were corneal ulcer, endophthalmitis and scleritis, which yielded positive culture of 31.1% (38/122 eyes), 24.2% (25/103 eyes), and 55.6% (5/9 eyes), respectively. Overall, positive cultures were demonstrated from 77 eyes (27%). Pseudomonas aeruginosa was the most common causative pathogens of corneal ulcer and scleritis, while Enterococcus faecalis was the most common pathogens of endophthalmitis. All isolated Pseudomonas spp. were susceptible to ciprofloxacin with 4% resistan...
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2009
Forty-two community and general hospitals in central Thailand. To examine the adequacy of indoor ... more Forty-two community and general hospitals in central Thailand. To examine the adequacy of indoor ventilation for nosocomial tuberculosis (TB) prevention in public hospitals in central Thailand. A cross-sectional survey was conducted among 323 patient care and ancillary areas in the target hospitals. Data on indoor ventilation rate were collected by the tracer gas method and reported as air changes per hour (ACH). The adequacy of the measured ventilation rates were then determined by comparison with the international recommended standard values. Indoor ventilation rates were inadequate in almost half of the studied areas (144/323, 44.6%). The inadequacy was particularly serious in the emergency rooms (ERs) and radiological areas, where 73.8% (31/42 each) of the rooms had ACH below the recommended standards. Detailed analysis showed that most of the rooms with natural ventilation had air exchange rates that exceeded the recommended standards, while the opposite was the case for rooms ...
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001
Sixty-eight children with systemic Streptococcus pneumoniae infection were identified by hospital... more Sixty-eight children with systemic Streptococcus pneumoniae infection were identified by hospital chart review between 1986-1997. The age distribution varied from 2 days to 15 years, with a mean age of 3.3 years. There were 35 boys and 33 girls. Four clinical entities included 30 cases of meningitis, 20 cases of pneumonia, 10 cases of peritonitis and 8 cases of septicemia/bacteremia. Forty patients (58.8%) had underlying diseases. Seventeen patients (25.0%) developed early complications and the mortality rate was 8.8 per cent. The percentage of susceptible isolates to penicillin, chloramphenicol, cefotaxime/ceftriaxone, ciprofloxacin, imipenem and vancomycin were 69.6, 91.3, 100.0, 87.2, 100.0 and 97.1 per cent, respectively. There were six cases of drug-resistant S. pneumoniae (DRSP) infection; 3 cases of meningitis, one case of pneumonia, one case of infective endocarditis and one case of purpura fulminans. Our data indicate that S. pneumoniae infection is relatively serious and l...
This study was to investigate and to characterize methicillin-resistant coagulase-positive staphy... more This study was to investigate and to characterize methicillin-resistant coagulase-positive staphylococci (MRCoPS) harboring in dogs and people associated with dogs in Thailand. Staphylococci were collected from 100 dogs, 100 dog owners, 200 small animal veterinarians and 100 people without pet association. Species of MRCoPS were identified phenotypically and genotypically. Molecular characteristics were determined by multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE) and SCCmec typing, and antimicrobial susceptibility was assayed by broth microdilution and by microarray analysis for resistance genes. Methicillin-resistant Staphylococcus pseudintermedius (MRSP), methicillin-resistant Staphylococcus schleiferi subsp. coagulans (MRSSc) and methicillin-resistant Staphylococcus aureus (MRSA) were isolated from dogs (45, 17 and 1%, respectively), veterinarians (8, 2 and 1·5%, respectively) and dog owners (3, 2 and 0%, respectively). Seventeen sequence types (STs) w...
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012
Nosocomial pneumonia (NP) is an important cause of morbidity and mortality in hospitalized patien... more Nosocomial pneumonia (NP) is an important cause of morbidity and mortality in hospitalized patients. Acinetobacter baumannii is one of the common causative pathogens in NP. The prevalence of multi-drug resistance in A. baumannii has been increasing. The information on clinical features and clinical courses of A. baumannii NP in Thai patients are limited. To determine the clinical features, risk factors and clinical courses of A. baumannii NP in Thai patients hospitalized in tertiary care hospitals in Thailand. This was a prospective, hospital-based, active surveillance study on hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) in adults hospitalized in 12 tertiary care hospitals in Thailand between 2008 and 2009. There were 651 NP patients. A. baumannii was the most common cause of NP in 198 patients (30.4%). Most of NP patients were males with median age of 71 years. About 80% had late onset NP with the median duration of 10 days after admission in both A....
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003
The emergence of hospital acquired infections with bacteria resistant to antimicrobials such as v... more The emergence of hospital acquired infections with bacteria resistant to antimicrobials such as vancomycin resistant enterococci (VRE) has become a worldwide concern. The authors studied the prevalence and surveillance of 5 years study of VRE in King Chulalongkon Memorial Hospital and phenotype of these resistance strains. A total of enterococci 1854 isolates were collected from clinical specimens from 1995 to 1999. Screening vancomycin resistance was identified by the agar plated method and minimal inhibitory concentration (MIC) of vancomycin was determined for vancomycin-resistance strains by E-test. The results demonstated that 15 (0.81%) VRE were isolated from 1,854 specimens. Fourteen VRE were identified as Enterococcus faecium and one strain was Enterococcus faecalis. All of these strains, carrying the VanB phenotype, were susceptible to teicoplanin. Similar to other studies, most VRE strains are E. faecium. To the authors' knowledge, this is the first VRE study carried ou...
The clinical and bacteriological efficacy of norfloxacin and co-trimoxazole was compared in patie... more The clinical and bacteriological efficacy of norfloxacin and co-trimoxazole was compared in patients with symptomatic upper urinary tract infections (UTI). Norfloxacin 400 mg or cotrimoxazole (160 mg of trimethoprim plus 800 mg of sulphamethoxazole) were given orally b.i.d. for seven days to 94 Thai patients. Clinical and bacteriological assessments were performed before and at 5, 14 and 21 days after start of treatment. Bacteriological outcome could be evaluated in 69 patients, 35 randomized to norfloxacin and 34 to co-trimoxazole. The bacteriological cure rate assessed four to seven days after treatment was significantly higher in the norfloxacin than in the co-trimoxazole group (94.3% vs. 73.5%; p less than 0.05). Few patients in each group reported mild and transient adverse effects. We conclude that norfloxacin was well tolerated and more effective than co-trimoxazole in the treatment of upper UTI.
Seventeen clinical isolates of Streptococcus pneumoniae showing reduced susceptibility to ciprofl... more Seventeen clinical isolates of Streptococcus pneumoniae showing reduced susceptibility to ciprofloxacin (MIC >/= 4 micro g/ml) collected from eight different Asian countries were analyzed by antimicrobial susceptibility, serotyping, pulsed-field gel electrophoresis (PFGE), and DNA sequencing of the quinolone resistance-determining regions (QRDRs) in gyrA, gyrB, parC, and parE. All isolates but one showed more than one amino acid alteration in QRDRs of four responsible genes. Ile460 --> Val in parE was the most common mutation. Data suggest that Lys137 --> Asn in parC may be a primary step in the development of high-level and multiple FQ resistance. An additional mutation of Ser81 --> Phe in gyrA resulted in high-level resistance to ciprofloxacin, levofloxacin, and gatifloxacin, whereas Ser79 --> Phe in parC may exert an important role in the development of moxifloxacin resistance. Two novel amino acid changes in gyrB, Ala390…
Background: Unnecessary use of antibiotics can be a problem in the treatment of hordeolum since t... more Background: Unnecessary use of antibiotics can be a problem in the treatment of hordeolum since the providers prescriptions, pathogens and their susceptibilies are peculiar to local situations. Objectives: We identified current pathogenic organisms in hordeolum and its susceptibilities to antimicrobial agents in topical eye medications in Thai patients. Methods: Seventy-nine patients from the King Chulalongkorn Memorial Hospital who never received any treatment for hordeolum participated in the study. Pus specimens were collected from incision and curettage. The bacteria was stained by Gram stain and grown on aerobic and anaerobic culture agars. If there was bacterial growth, drug susceptibility test was conducted utilizing Ciprofloxacin, Fusidic acid, Oxytetracycline, Polymyxin, Neomycin, and Chloramphenicol. Results: Bacterial growth was detected in 54 isolates from 50 patients (63.3%). These isolates were identified to be Staphylococcus epidermidis (19 isolates, 35.2%), Proprioni...
bial Agents publishes original research articles, case reports and article reviews on various asp... more bial Agents publishes original research articles, case reports and article reviews on various aspects of infectious diseases and antimicrobial agents. The contributions submitted to this journal should not be published else where in whole or in part, without the Editor’s permission. Accepted contributions become the copyright of Journal. Manuscripts should be accompanied by a covering letter from the author who is responsible for correspon-dence regarding the manuscript. The covering letter should contain a statement that the manuscript has been approved by all authors. A manuscript, tables and illustrations should be sent in duplicate together with a
Performance of an immunochromatography kit (IC kit) for detection of the white spot virus in cult... more Performance of an immunochromatography kit (IC kit) for detection of the white spot virus in cultured shrimp was evaluated. The IC kit’s virus detection rate was similar to that of the one-step PCR method, but lower than that of the two-step PCR method. The antibody included in the IC kit recognized the white spot virus (WSV) envelope protein VP28, and the assay had a detection limit of 9.9×10 viral DNA copies/μl. Compared to detection based on gross and histopathological examination, this assay could detect virus even from shrimps without apparent disease signs and also few virus positive cells in the stomach and gills. When infected cultured shrimp from various countries and several other infected crustaceans were tested using the IC kit as well as onestep PCR, the IC kit was proven as a more rapid diagnostic tool.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2008
BACKGROUND AND PURPOSE Shigellosis is a major health problem in developing countries, causing 91 ... more BACKGROUND AND PURPOSE Shigellosis is a major health problem in developing countries, causing 91 million episodes and 414,000 deaths in Asia annually. Because of increasing trends towards drug resistance, this study was undertaken to monitor local resistance patterns of Shigella isolates from 8 Asian countries. METHODS Ninety eight Shigella isolates collected from 8 centers in 8 Asian countries from July 2001 to July 2004 were analyzed in terms of serogroup distribution and antimicrobial susceptibility. RESULTS The most common serogroup of Shigella isolates was Shigella flexneri (49/98, 50%), followed by Shigella sonnei (44/98, 45%). The highest resistance rate was found for trimethoprim-sulfamethoxazole (81%), followed by tetracycline (74%) and ampicillin (53%). Overall, 76 Shigella isolates (78%) were multidrug-resistant strains; S. flexneri had a higher multidrug resistance rate than S. sonnei (74% vs 23%). Increasing ciprofloxacin and ceftriaxone resistance was observed; approxi...
OBJECTIVE To study the profiles and antimicrobial susceptibility pattern of isolated bacteria fro... more OBJECTIVE To study the profiles and antimicrobial susceptibility pattern of isolated bacteria from visual threatening ocular infection. MATERIAL AND METHOD This is a retrospective review of all microbiological culture reports from visual threatening ocular infection patients admitted at King Chulalongkorn Memorial Hospital from 2005 to 2009. The culture reports with antimicrobial susceptibility pattern were analyzed and correlated with clinical presentation. RESULTS There were 682 specimens from 282 patients (286 eyes). Three most common diagnoses were corneal ulcer, endophthalmitis and scleritis, which yielded positive culture of 31.1% (38/122 eyes), 24.2% (25/103 eyes), and 55.6% (5/9 eyes), respectively. Overall, positive cultures were demonstrated from 77 eyes (27%). Pseudomonas aeruginosa was the most common causative pathogens of corneal ulcer and scleritis, while Enterococcus faecalis was the most common pathogens of endophthalmitis. All isolated Pseudomonas spp. were suscept...
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015
To study the profiles and antimicrobial susceptibility pattern of isolated bacteria from visual t... more To study the profiles and antimicrobial susceptibility pattern of isolated bacteria from visual threatening ocular infection. This is a retrospective review of all microbiological culture reports from visual threatening ocular infection patients admitted at King Chulalongkorn Memorial Hospital from 2005 to 2009. The culture reports with antimicrobial susceptibility pattern were analyzed and correlated with clinical presentation. There were 682 specimens from 282 patients (286 eyes). Three most common diagnoses were corneal ulcer, endophthalmitis and scleritis, which yielded positive culture of 31.1% (38/122 eyes), 24.2% (25/103 eyes), and 55.6% (5/9 eyes), respectively. Overall, positive cultures were demonstrated from 77 eyes (27%). Pseudomonas aeruginosa was the most common causative pathogens of corneal ulcer and scleritis, while Enterococcus faecalis was the most common pathogens of endophthalmitis. All isolated Pseudomonas spp. were susceptible to ciprofloxacin with 4% resistan...
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2009
Forty-two community and general hospitals in central Thailand. To examine the adequacy of indoor ... more Forty-two community and general hospitals in central Thailand. To examine the adequacy of indoor ventilation for nosocomial tuberculosis (TB) prevention in public hospitals in central Thailand. A cross-sectional survey was conducted among 323 patient care and ancillary areas in the target hospitals. Data on indoor ventilation rate were collected by the tracer gas method and reported as air changes per hour (ACH). The adequacy of the measured ventilation rates were then determined by comparison with the international recommended standard values. Indoor ventilation rates were inadequate in almost half of the studied areas (144/323, 44.6%). The inadequacy was particularly serious in the emergency rooms (ERs) and radiological areas, where 73.8% (31/42 each) of the rooms had ACH below the recommended standards. Detailed analysis showed that most of the rooms with natural ventilation had air exchange rates that exceeded the recommended standards, while the opposite was the case for rooms ...
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001
Sixty-eight children with systemic Streptococcus pneumoniae infection were identified by hospital... more Sixty-eight children with systemic Streptococcus pneumoniae infection were identified by hospital chart review between 1986-1997. The age distribution varied from 2 days to 15 years, with a mean age of 3.3 years. There were 35 boys and 33 girls. Four clinical entities included 30 cases of meningitis, 20 cases of pneumonia, 10 cases of peritonitis and 8 cases of septicemia/bacteremia. Forty patients (58.8%) had underlying diseases. Seventeen patients (25.0%) developed early complications and the mortality rate was 8.8 per cent. The percentage of susceptible isolates to penicillin, chloramphenicol, cefotaxime/ceftriaxone, ciprofloxacin, imipenem and vancomycin were 69.6, 91.3, 100.0, 87.2, 100.0 and 97.1 per cent, respectively. There were six cases of drug-resistant S. pneumoniae (DRSP) infection; 3 cases of meningitis, one case of pneumonia, one case of infective endocarditis and one case of purpura fulminans. Our data indicate that S. pneumoniae infection is relatively serious and l...
This study was to investigate and to characterize methicillin-resistant coagulase-positive staphy... more This study was to investigate and to characterize methicillin-resistant coagulase-positive staphylococci (MRCoPS) harboring in dogs and people associated with dogs in Thailand. Staphylococci were collected from 100 dogs, 100 dog owners, 200 small animal veterinarians and 100 people without pet association. Species of MRCoPS were identified phenotypically and genotypically. Molecular characteristics were determined by multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE) and SCCmec typing, and antimicrobial susceptibility was assayed by broth microdilution and by microarray analysis for resistance genes. Methicillin-resistant Staphylococcus pseudintermedius (MRSP), methicillin-resistant Staphylococcus schleiferi subsp. coagulans (MRSSc) and methicillin-resistant Staphylococcus aureus (MRSA) were isolated from dogs (45, 17 and 1%, respectively), veterinarians (8, 2 and 1·5%, respectively) and dog owners (3, 2 and 0%, respectively). Seventeen sequence types (STs) w...
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012
Nosocomial pneumonia (NP) is an important cause of morbidity and mortality in hospitalized patien... more Nosocomial pneumonia (NP) is an important cause of morbidity and mortality in hospitalized patients. Acinetobacter baumannii is one of the common causative pathogens in NP. The prevalence of multi-drug resistance in A. baumannii has been increasing. The information on clinical features and clinical courses of A. baumannii NP in Thai patients are limited. To determine the clinical features, risk factors and clinical courses of A. baumannii NP in Thai patients hospitalized in tertiary care hospitals in Thailand. This was a prospective, hospital-based, active surveillance study on hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) in adults hospitalized in 12 tertiary care hospitals in Thailand between 2008 and 2009. There were 651 NP patients. A. baumannii was the most common cause of NP in 198 patients (30.4%). Most of NP patients were males with median age of 71 years. About 80% had late onset NP with the median duration of 10 days after admission in both A....
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003
The emergence of hospital acquired infections with bacteria resistant to antimicrobials such as v... more The emergence of hospital acquired infections with bacteria resistant to antimicrobials such as vancomycin resistant enterococci (VRE) has become a worldwide concern. The authors studied the prevalence and surveillance of 5 years study of VRE in King Chulalongkon Memorial Hospital and phenotype of these resistance strains. A total of enterococci 1854 isolates were collected from clinical specimens from 1995 to 1999. Screening vancomycin resistance was identified by the agar plated method and minimal inhibitory concentration (MIC) of vancomycin was determined for vancomycin-resistance strains by E-test. The results demonstated that 15 (0.81%) VRE were isolated from 1,854 specimens. Fourteen VRE were identified as Enterococcus faecium and one strain was Enterococcus faecalis. All of these strains, carrying the VanB phenotype, were susceptible to teicoplanin. Similar to other studies, most VRE strains are E. faecium. To the authors' knowledge, this is the first VRE study carried ou...
Uploads
Papers by Anan Chongthaleong