maggiore suscettibilità a sviluppare una dipendenza affettiva in coloro che abbiano già esperito ... more maggiore suscettibilità a sviluppare una dipendenza affettiva in coloro che abbiano già esperito un Disturbo da Uso di Sostanze. Metodi:A centosedici soggetti con Dipendenza da Alcol (DSM IV-TR) e a centocinquanta controlli non clinici omogenei per caratteristiche socio-demo-grafiche sono stati somministrati un questionario per lo screening delle condotte di dipendenza affettiva ed il Temperamental and Character Inventory-Revised version (TCI-R) per identificare le dimensioni temperamentali e caratteriali ad essa maggiormente associate. Risultati: Il 13% dei soggetti alcol-dipendenti ed il 2,7% dei controlli non clinici hanno raggiunto il cut-off per lo screening di comportamenti orientati alla dipendenza affettiva. Inoltre, sono state evidenziate correlazioni significative tra i punteggi riportati al questionario per la dipendenza affettiva e le dimensioni tem-peramentali Novelty Seeking, Harm Avoidance e Self-Trascendence e caratteriali Self-Directedness valutate mediante il TCI-R...
The rationale of this article is to emphasize the importance of cognitive assessment in the manag... more The rationale of this article is to emphasize the importance of cognitive assessment in the management of psychiatric syndromes. Many studies have investigated and have clearly shown the existence of cognitive dysfunction in most of the psychiatric disorders. These deficits occur with different severity which seems to trace a dimensional continuum between the various clinical manifestations. Cognitive impairment is not merely a result of the damage caused during the time by the psychiatric symptoms but an integral part of the disorder itself. The alterations of different cognitive domains found in mental illnesses are often detectable as prodromal symptoms of the disease, showing indirectly a predisposition to the later development of the disorder, particularly schizophrenia. Considering that cognitive impairment is not only a feature of schizophrenia but also of affective psychoses and bipolar disorder, some authors have suggested using the cognitive impairment as an endophenotype....
To date, a limited number of pharmacological agents exist to treat alcohol use disorders (AUDs), ... more To date, a limited number of pharmacological agents exist to treat alcohol use disorders (AUDs), and there is growing interest in new therapeutic tools. In this framework, topiramate may represent a useful treatment option, although its use is not yet approved for AUDs. The main focus of this review is to discuss all the existing data supporting the use of topiramate in AUDs, with an emphasis on the most recent and relevant clinical implications. In addition, the profile of the alcoholic patient who may benefit more from the use of topiramate is outlined. In this regard, the authors conducted a PubMed search of clinical human studies published in English using the following key words: topiramate alcohol dependence, topiramate alcohol withdrawal and topiramate alcoholism. The evidence suggests that topiramate could be an effective treatment option for the management of AUDs, while there are limited results for its use to treat alcohol withdrawal syndrome. In particular, topiramate sh...
maggiore suscettibilità a sviluppare una dipendenza affettiva in coloro che abbiano già esperito ... more maggiore suscettibilità a sviluppare una dipendenza affettiva in coloro che abbiano già esperito un Disturbo da Uso di Sostanze. Metodi:A centosedici soggetti con Dipendenza da Alcol (DSM IV-TR) e a centocinquanta controlli non clinici omogenei per caratteristiche socio-demo-grafiche sono stati somministrati un questionario per lo screening delle condotte di dipendenza affettiva ed il Temperamental and Character Inventory-Revised version (TCI-R) per identificare le dimensioni temperamentali e caratteriali ad essa maggiormente associate. Risultati: Il 13% dei soggetti alcol-dipendenti ed il 2,7% dei controlli non clinici hanno raggiunto il cut-off per lo screening di comportamenti orientati alla dipendenza affettiva. Inoltre, sono state evidenziate correlazioni significative tra i punteggi riportati al questionario per la dipendenza affettiva e le dimensioni tem-peramentali Novelty Seeking, Harm Avoidance e Self-Trascendence e caratteriali Self-Directedness valutate mediante il TCI-R...
The rationale of this article is to emphasize the importance of cognitive assessment in the manag... more The rationale of this article is to emphasize the importance of cognitive assessment in the management of psychiatric syndromes. Many studies have investigated and have clearly shown the existence of cognitive dysfunction in most of the psychiatric disorders. These deficits occur with different severity which seems to trace a dimensional continuum between the various clinical manifestations. Cognitive impairment is not merely a result of the damage caused during the time by the psychiatric symptoms but an integral part of the disorder itself. The alterations of different cognitive domains found in mental illnesses are often detectable as prodromal symptoms of the disease, showing indirectly a predisposition to the later development of the disorder, particularly schizophrenia. Considering that cognitive impairment is not only a feature of schizophrenia but also of affective psychoses and bipolar disorder, some authors have suggested using the cognitive impairment as an endophenotype....
To date, a limited number of pharmacological agents exist to treat alcohol use disorders (AUDs), ... more To date, a limited number of pharmacological agents exist to treat alcohol use disorders (AUDs), and there is growing interest in new therapeutic tools. In this framework, topiramate may represent a useful treatment option, although its use is not yet approved for AUDs. The main focus of this review is to discuss all the existing data supporting the use of topiramate in AUDs, with an emphasis on the most recent and relevant clinical implications. In addition, the profile of the alcoholic patient who may benefit more from the use of topiramate is outlined. In this regard, the authors conducted a PubMed search of clinical human studies published in English using the following key words: topiramate alcohol dependence, topiramate alcohol withdrawal and topiramate alcoholism. The evidence suggests that topiramate could be an effective treatment option for the management of AUDs, while there are limited results for its use to treat alcohol withdrawal syndrome. In particular, topiramate sh...
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