Authors: Minervini, Giuseppe | Cervino, Gabriele | Chaturvedi, Saurabh | Franco, Rocco | di Francesco, Fabrizio | Fiorillo, Luca | Cicciù, Marco
Article Type: Review Article
Abstract: BACKGROUND: Edentulism conducts to a recognized impairment of oral function with both aesthetic and psychological changes. These patients suffer from a multiplicity of problems with their dentures, such as insufficient stability, retention and pain during mastication. The rehabilitation of a part edentulous patient can be established using a wide range of prosthetic treatment options. The overdenture treatment uses a removable total denture that overlies retained teeth, tooth roots, or dental implants. In the literature it was shown that patients with removable overdentures supported and retained either by tooth roots or implants have more predictable prosthodontic outcomes. OBJECTIVE: The aim of …this review is to provide an overview on the overdenture with a focus on the tooth-supported telescopic overdenture. METHODS: The literature research was performed in the Scopus, Web of Science, and Pubmed electronic databases. Document type was limited to papers written in English, without time restrictions. The Review was recorded in the international PROSPERO (International Prospective Register of Systematic Reviews) database with the following number CRD42022326415. RESULTS: A total of 256 articles published were found from electronic searches, Two independent reviewers carried out the screening and the selection process for the studies. First, duplicate citations were eliminated. Then, the two Authors independently screened the retrieved articles by title and abstract of each citation to determine its suitability for inclusion. Finally, 13 full-text articles satisfied the inclusion criteria. CONCLUSION: Prostheses supported by Frictional telescopic crowns offer an effective treatment alternative for patients with Severely reduced dentitions who do not want implant treatment or complete dentures. Show more
Keywords: Jaw rehabilitation, overdenture, tooth-supported telescopic, full arch rehabilitation, implant
DOI: 10.3233/THC-220641
Citation: Technology and Health Care, vol. 31, no. 3, pp. 791-807, 2023
Authors: Juodzbalys, Gintaras | Kasradze, David | Cicciù, Marco | Sudeikis, Aurimas | Banys, Laurynas | Galindo-Moreno, Pablo | Guobis, Zygimantas
Article Type: Research Article
Abstract: INTRODUCTION: Nearly half of the head and neck cancer cases are diagnosed in late stages. Traditional screening modalities have many disadvantages. The aim of the present article was to review the scientific literature about novel head and neck cancer diagnostics - epigenetic biomarkers. EVIDENCE ACQUISITION: A comprehensive review of the current literature was conducted according to the PRISMA guidelines by accessing the NCBI PubMed database. Authors conducted the search of articles in English language published from 2004 to 2015. EVIDENCE SYNTHESIS: A total of thirty three relevant studies were included in the review. Fifteen of them concerned DNA methylation alterations, …nine evaluation of abundancies in histone expressions and nine miRNA expression changes in HNC. CONCLUSIONS: Considerable number of epigenetic biomarkers have been identified in both tumor tissue and salivary samples. Genes with best diagnostic effectiveness rates and further studying prospects were: TIMP3, DCC, DAPK, CDH1, CCNA1, AIM1, MGMT, HIC1, PAX1, PAX5, ZIC4, p16, EDNRB, KIF1A, MINT31, CD44, RARβ , ECAD. Individual histone and miRNA alterations tend to be hnc specific. Prognostic values of separate biomarkers are ambiguous. No established standards for molecular assay of head and neck cancer was found in order to elude the paradoxical results and discrepancies in separate trials. Show more
Keywords: Head and neck cancer, DNA methylation, head and neck cancer histone, head and neck cancer miRNA
DOI: 10.3233/CBM-160666
Citation: Cancer Biomarkers, vol. 17, no. 4, pp. 487-502, 2016
Authors: Porwal, Amit | Al Moaleem, Mohammed M. | Adawi, Hafiz Ahmed | Nandalur, Kulashekar Reddy | Satpathy, Anurag | Mehta, Vini | Cicciù, Marco | Minervini, Giuseppe
Article Type: Review Article
Abstract: BACKGROUND: Various studies have been conducted to analyze data via bibliometric analysis in different dentistry, including prosthetic dentistry. However, these studies evaluated the most cited published articles in dentistry. OBJECTIVE: To analyze and evaluate the characteristic development of several mesh keywords in the Journal of Prosthodontics – Implant, Esthetic, and Reconstructive Dentistry between 1992 and 2022. METHODS: The Scopus databases was searched to retrieve the data related to 8 categories, including published articles, most cited documents, authors and organizations, and maximum articles cited during the evaluation period. The data retrieved were exported to a Microsoft Excel sheet and were analyzed using …the bibliometrix package. The data were first analyzed for ten years and then for 30 years. The highest of 10 were reported for each category, and co-authorship, reoccurrence, and linked data were also reported. RESULTS: 2603 published documents were recorded from the Scopus databases. Articles comprised 87.9% of the total published work, followed by review articles at 5.46%. The most productive decade was between 2013 and 2022. 3793 terms were used during the evaluation period, with the maximum number in 2003–2012 (2481). A total of 5392 keywords were used during 1992–2022, with the highest number (3232) from 2013 to 2022. A total of 6108 authors were acknowledged, with the maximum number (3964) from 2013 to 2022 and the fewest (767) from 1992 to 2002. Authors from different countries increased from 17 countries in 1992–2002 to 52 countries in 2013–2022 (total = 63 countries). Similarly, the number of organizations increased from 312 organizations in 1992–2002 to 1315 organizations in 2013–2022 (total = 1976 organizations). CONCLUSION: The current bibliometric analysis delivered a comprehensive overview about more spread research topics and its impactful role in contemporary dentistry, especially prosthetic dentistry. Show more
Keywords: Bibliographic analysis, citation index, bibliometrix package, prosthesis, implant
DOI: 10.3233/THC-230204
Citation: Technology and Health Care, vol. 32, no. 1, pp. 343-359, 2024
Authors: Maheshwaran, Bipin | Chokkatt, Jerry Joe | Shenoy, Amrutha | Ganapathy, Dhanraj | Yadalam, Pradeep Kumar | Marrapodi, Maria Maddalena | Cicciù, Marco | Minervini, Giuseppe
Article Type: Research Article
Abstract: BACKGROUND: Titanium nanoparticles (NPs) offer promising applications in the treatment and prevention of inflammatory disorders due to their unique physicochemical characteristics. However, additional research is necessary to attain a thorough comprehension and validate the efficacy of this approach in dental practice. OBJECTIVE: This study scrutinizes the anti-inflammatory properties of a dental varnish infused with ginger and rosemary extracts mediated by titanium dioxide (TiO2) nanoparticles. METHODS: A herbal dental varnish was formulated by integrating ginger and rosemary extracts with titanium dioxide nanoparticles at concentrations of 10, 20, 30, 40, and 50 μ L. Anti-inflammatory properties were assessed through Bovine Serum Albumin denaturation …and membrane stabilization assays, comparing results with a control group. RESULTS: The results reveal concentration-dependent antioxidant and anti-inflammatory properties in the test group when compared to the control group. The BSA assay corroborates increased percent inhibition with rising titanium dioxide nanoparticle concentrations. In line with existing literature, titanium dioxide nanoparticles enhance dental material properties. CONCLUSION: The bioactive compounds in ginger and rosemary, such as phenolic compounds and terpenes, contribute to anti-inflammatory and antioxidant effects of the varnish. Additionally, the therapeutic potential of titanium dioxide nanoparticles in addressing inflammatory diseases underscores their significance in this formulation. Show more
Keywords: Preventive dentistry, nanoparticles, titanium dioxide, green synthesis, antioxidant
DOI: 10.3233/THC-231994
Citation: Technology and Health Care, vol. 32, no. 4, pp. 2783-2792, 2024
Authors: Jadhav, Shreya | Jhaveri, Aditi | Pawar, Ajinkya M. | Bhardwaj, Anuj | Vinay, Vineet | di Blasio, Marco | Cicciù, Marco | Minervini, Giuseppe
Article Type: Research Article
Abstract: BACKGROUND: Forensic odontology is a subfield of forensics that can assist in determining age, gender, and other demographic factors. OBJECTIVE: The focus of this research is to ascertain age by tooth volume ratio of permanent maxillary canines using a CBCT scan. METHODS: In this retrospective investigation, 1000 CBCT images were gathered and focused on only fully developed maxillary canines. For each of the maxillary canines, the researchers measured and calculated the volume of the pulp chamber, root canal, and entire tooth using the ITK Snap programme. The pulp volume to tooth volume ratio was computed. The equation AGE = 59.208 …- (583.652 x pulp volume/tooth volume) was then used to compute age. The samples were divided into 5 age groups; 13–20, 21–30, 31–40, 41–50, and 51–60. The age was calculated for samples in each group and it was compared to the actual age. RESULTS: Between individuals’ actual age and computed age, the study discovered a statistically significant positive association. While groups 3, 4, and 5 demonstrated positive but weaker correlations (r = 0.854, r = 0.658, and r = 0.612, respectively), groups 1 and 2 displayed statistically significant strong positive correlations (r = 0.987 and r = 0.923, respectively). The average total discrepancy between the age that was computed and the actual age was 2.45 1.344. CONCLUSION: The study found a statistically significant positive correlation between computed age and actual age, with the younger age groups 1 (13–20) and 2 (21–30) showing the strongest relationships. This underlines its potential success in court, particularly when dealing with young criminals. Show more
Keywords: Age estimation, canines, cone-beam computed tomography, forensic odontology, pulp tooth volume
DOI: 10.3233/THC-230555
Citation: Technology and Health Care, vol. 32, no. 4, pp. 2057-2067, 2024
Authors: Mathew, Vinod Babu | Shamsuddin, Shaheen | Langaliya, Akshayraj | Rathod, Priyanka Tikaram | Gupta, Bharti | Ronsivalle, Vincenzo | Cicciù, Marco | Minervini, Giuseppe
Article Type: Review Article
Abstract: BACKGROUND: Literature evidence describes various treatment protocols that have been employed for the effectiveness in improving survival and addressing associated symptoms of cracked teeth. OBJECTIVE: This systematic review investigates the survivability of endodontically treated cracked teeth and associated assessments, focusing on various treatment protocols. METHODS: The PRISMA guidelines were utilised for guiding the article selection framework of this review. A comprehensive search of relevant literature was conducted in May 2023 across various databases, and studies meeting the inclusion criteria were selected. Data extraction, guided by a standardized form, captured crucial details, including study characteristics, treatment protocols, and treatment outcomes, enhancing …the consistency and accuracy of information collection. Data extraction and synthesis was done by two reviewers independently. The Newcastle Ottawa tool was used to measure the methodological quality of the study. Six observational studies were eventually included. RESULTS: Mandibular molars are particularly prone to developing cracks, with research indicating a heightened susceptibility to this dental issue. Studies reveal that endodontically treated cracked teeth boast robust overall survival rates ranging from 75.8% to 100%. The risk of bias assessment, utilizing the Newcastle Ottawa scale, indicated a moderate risk across studies, highlighting the necessity for careful interpretation of findings. CONCLUSION: Endodontically treated cracked teeth show marked success in survival, with the incorporation of crowns post-endodontic treatment significantly enhancing longevity and resilience. Show more
Keywords: Cracked teeth, survivability, treatment protocols, tooth survival, pulpitis, periodontitis, fractures
DOI: 10.3233/THC-231993
Citation: Technology and Health Care, vol. 32, no. 4, pp. 2023-2037, 2024
Authors: Zeeshan, Tayyaba | Qamar, Zeeshan | Abdul, Nishath Sayed | Soman, Cristalle | Bamousa, Badr | Marrapodi, Maria Maddalena | Cicciù, Marco | Minervini, Giuseppe
Article Type: Research Article
Abstract: BACKGROUND: Commercially available oral rinses contain active ingredients with concentration that is claimed by manufacturers to be effective as antiplaque agent. To date there has been no mention of the effect of oral rinse on the adherence of early plaque colonizers in plaque formation and the concentration to be used before/after meals. OBJECTIVE: The chief aim of the study was to evaluate microbial retention on the salivary pellicle on treatment with oral rinses (CHX & EO)/PS (mimicking after meals use of mouth wash/PS). METHODS: Noordini’s Artifical Mouth model was used for developing the single species biofilm with early microbial colonizers …of oral biofilm (A. viscosus , Strep. mitis and Strep. sanguinis respectively). The microbial retention on use of oral rinses comprising of CHX and EO as an active ingredients respectively was compared with Curcumin PS. For evaluating the microbial retention, the pellicle with microbial inoculation was developed on the glass beads in the mouth model. Subsequently the respective single specie biofilm was exposed to the mouth wash and PS after inoculation. It mimicked as use of mouth wash/PS after meals. The bacterial count in the dental biofilm was evaluated on serial dilution (CFU/ml). Sterile deionized water was used as a negative control. For qualitative analysis, Scanning electron microscope (SEM) was used to evaluate the microbial count. RESULTS: From the data it was observed that for the treatment of single species experimental biofilm with commercially available mouth rinses (CHX & EO) and PS (curcumin), there was significant retention for S.mitis , S.sanguinis and A.viscosus . There was no significant difference observed between PS and CHX treated single species biofilm. Whereas a significant difference was observed between EO treated biofilms and CHX/PS treated biofilms (p ⩽ 0.05). CONCLUSION: It can be concluded from the results that curcumin PS and CHX should not be used after meals whereas EO containing mouth rinse can be used to maintain the oral mocroflora. Show more
Keywords: Bacterial retention, essential oils, chlorhexidine gluconate, curcumin photosensitizer
DOI: 10.3233/THC-231814
Citation: Technology and Health Care, vol. 32, no. 4, pp. 2685-2696, 2024
Authors: Mittal, Priya | Jadhav, Ganesh Ranganath | Abdul Kader M, Mohammed | Al-Qarni, Mohammed A. | Sindi, Abdulelah Sameer | Cicciù, Marco | Minervini, Giuseppe
Article Type: Research Article
Abstract: BACKGROUND: Dental education is considered as a complex, challenging and often stressful educational procedure. Acquisition of psychomotor skills by undergraduate students is an important step in many health professions to become a successful professional. During under graduation, class II cavity preparation exercise is of utmost important in dentistry. OBJECTIVE: To compare class II cavities prepared by students after hands-on live demonstration and pre-recorded video demonstration using well-organised evaluation rubrics. METHOD: Preclinical dental students (n = 50) were divided into two groups. The students in group I (n = 25) attended a hands-on live demonstration performed by one faculty while students …in group II (n = 25) watched a 15-minute pre-recorded procedural video on the projector. Both groups were appealed to prepare class II cavity for amalgam involving disto-occlusal surface of mandibular second molar articulated on jaw model (TRU LON study model, Jayna industries, Ghaziabad U.P., India). Following completion of the preparations, all teeth were collected, and labelled grades of prepared cavities were given according to prespecified rubrics. The data of scores were presented as means and standard deviation. Statistical analysis of data was executed using SPSS software. A paired t-test was used to compare scores between groups. RESULTS: The study shows that the video-supported demonstration of a cavity preparation was better than the live hands-on demonstration. A higher mean response for the procedural video group was found compared to the live demonstration group (p = 0.000133). CONCLUSION: Pre-recorded video-supported demonstration along with guidance by a tutor may be a viable alternative to hands-on live demonstration in cavity preparation procedures during undergraduate dental training. Moreover, rubric methods can be implemented in the teaching of various preclinical exercises for conservative dentistry and endodontics. Show more
Keywords: Dental undergraduates, educational measurement, education, dental, hands-on demonstration, video recording
DOI: 10.3233/THC-231757
Citation: Technology and Health Care, vol. 32, no. 5, pp. 3109-3117, 2024
Authors: Rafeeq, Reem A. | Saleem, Alan E. | Nahidh, Mohammed | Kadhum, Ammar S. | Al-Huwaizi, Akram F. | Marrapodi, Maria Maddalena | Cicciù, Marco | Minervini, Giuseppe
Article Type: Research Article
Abstract: BACKGROUND: SARS-CoV-2 (COVID-19) is considered a highly infectious and life threatening disease. OBJECTIVE: The present paper aims to evaluate various aspects of preventive measures and clinical management of the scheduled visits for orthodontic patients to the dental clinics during the outbreak of COVID-19, and to assess how orthodontists dealt with this challenge. METHODS: Orthodontists in private and public clinics were invited to fill a questionnaire that addressed infection control protocols and concerns about clinical management of patients in the clinics during the pandemic. Frequncies and percentages of the responses were obtained and compared using Chi-square tests. RESULTS: About 77% of …those working in private clinics, and 63% of those working in private and governmental clinics performed room disinfection following each patient. In case of patients needing urgent management and have active infection, 56% of the participants provided care under high infection control measures; on the contrary, 64% provided symptomatic intervention including orthodontic wax, analgesics and sometimes mouthwash. CONCLUSION: The COVID-19 pandemic has had a negative impact on the orthodontic treatments. All pre-cautionary measures have to be made available in the clinic in order to minimize the spread of viral infection with continuous dental health care training. Show more
Keywords: COVID-19, infection control, orthodontics
DOI: 10.3233/THC-220909
Citation: Technology and Health Care, vol. 31, no. 5, pp. 1579-1592, 2023
Authors: Elrashid, Afra Hassan | Alsarh, Sarah Ahmad | Alotaibi, Dalia Saleh | Albaqami, Majed Adi | Algadhi, Saleh Khalid | Alfaraj, Reham Ahmad | Cicciù, Marco | Minervini, Giuseppe
Article Type: Research Article
Abstract: BACKGROUND: Bleaching is a highly common method used nowadays to treat tooth discolouration because it is a significant cosmetic issue, particularly with anterior teeth, however bleaching itself results in microleakage. OBJECTIVE: This study aims to evaluate the impact of in-office bleaching on class V restoration microleakage with type 1 and type 2 composite restorations. METHODS: Three hundred and twenty healthy, caries-free removed human anterior teeth were used in this in-vitro study. All extracted teeth had their buccal and lingual surfaces uniformly prepped for class V cavities. The 120 removed teeth were divided into two groups, with Group 1 receiving Tetric …N-Ceram nanohybrid composite restorations and Group 2 receiving 3 M Filtek Z350 XT nanohybrid composite restorations. Groups 1 and 2 were further broken into four more subgroups of four each. The restorations were sealed with a G-Coat Plus resin. The p -value was kept at 0.005 for the data analysis using the Chi-square and Fisher exact tests. RESULTS: Allocating microleakage among 320 study models revealed that 141 (44.1%) study samples had no microleakage, whereas 20 (6.3%), 54 (16.9%), and 105 (32.8%) study samples had microleakage up to, between, and greater than two-thirds of cavity depth. With a statistically significant p -value of 0.001, no microleakage was discovered in 85 (53.1%) lingual surfaces with Tetric N-Ceram nanohybrid composite restoration and 56 (35%) buccal surfaces with 3M Filtek Z350 XT nanohybrid composite restoration. 19.1% of samples of N-Ceram that were sealed and not bleached had no microleakage, according to analysis of microleakage across several groups. With a p -value of 0.001, the distribution of microleakage among various clusters was statistically notable. CONCLUSION: According to the findings of the study, hydrogen peroxide bleaching has an enhanced impact on micro escape during dye dispersion. Both with and without bleaching, resin coating can be utilised to minimise marginal microleakage. Show more
Keywords: Microleakage, resins, bleaching, composite restorations
DOI: 10.3233/THC-230213
Citation: Technology and Health Care, vol. 32, no. 2, pp. 787-798, 2024
