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Authors: Zhang, Cong | Wang, Heng

Article Type: Research Article

Abstract: Three-dimensional sound effects require a considerable number of sound channels, causing audio-visual spatial orientation sense distortion under circumstances in which the code rate is restricted by the limitation of transmission channel bandwidth and storage capacity. As a result, existing 3D audio systems are incompatible with real-time broadcasting and home theatre applications, severely limiting the application and development of 3D audio systems. By investigating the mechanism of orientation parameters perceptual redundancy, this paper studied 3D spatial orientation cue perceptual characteristics, established an orientation cue perceptual model, developed a heterogeneous quantification table accordingly, and controlled the differences between each quantified value below …the quantitative value perception threshold. Using this method, only the information perceptible to the human ear was quantified and perceptual distortions were minimized. The experimental results revealed that, compared to the SLQP method, the quantified bit of the proposed method was reduced by 8.66% in low resolution and 65.23% in high resolution. In addition, the accuracy of this method was higher than that of the SLQP method, enabling better alignment with human perceptual characteristics. Show more

Keywords: 3D Audio, orientation cue, perceptual characteristic, parameter coding

DOI: 10.3233/IFS-151976

Citation: Journal of Intelligent & Fuzzy Systems, vol. 29, no. 6, pp. 2727-2736, 2015

Authors: Zhang, Cong | Zhang, Jun

Article Type: Research Article

Abstract: We discuss the interpolation strategies related to Richardson extrapolation and repeated Richardson extrapolation. We emphasize that, in most computations, the interest is in obtaining accurate solution on the current computational grid, not that on the coarse level grids on which the extrapolated solutions reside. We tackle the interpolation issue that has largely been overlooked in Richardson extrapolation related applications. We present numerical experiments to support our analysis.

Keywords: Computational grid, finite difference scheme, Richardson extrapolation, interpolation, high order solution

DOI: 10.3233/JIFS-169177

Citation: Journal of Intelligent & Fuzzy Systems, vol. 31, no. 6, pp. 2935-2939, 2016

Authors: Wang, Heng | Wu, Yafei | Zhang, Cong | Tu, Weiping

Article Type: Research Article

Abstract: The rapid development of 3D video inspired the demand for 3D audio technology and products, but the products on the market currently are difficult to produce a real 3D audio effect synchronized with 3D videos. This article derive generating principles and formulas for movable virtual sound source base on VBAP and Clustering in the 3D sound field, design and implement the method to generate 3D Audio Content, the produced virtual sound source could customize different trajectories and speed in the 3D sound field. As to different 3D audio systems, after modify the corresponding parameters according to the allocation model, could generate …suitable 3D audio and make audiences feel ubiquitous audio-visual enjoyment. After field tests in the 3D sound field, the movement of the movable virtual sound source generated by this method is obvious and stable, vastly improves the efficiency and accuracy compared with manual method, provide a high efficiency generating method for related film creation. Show more

Keywords: 3D Content, clustering, VBAP, NHK 22.2 system

DOI: 10.3233/JIFS-169206

Citation: Journal of Intelligent & Fuzzy Systems, vol. 31, no. 6, pp. 3203-3210, 2016

Authors: Zhang, Cong Xiao | Falentin-Daudre, Celine | Migonney, Veronique

Article Type: Research Article

Abstract: Background: Osseointegration of implant materials with surrounding tissues is crucial for their long-term success. Objective: The aim of the present study was to investigate the extent of physisorption of polymers on a titanium alloy (Ti6Al4V) surface. In addition, the water contact angles on the physisorbed coatings were measured to compare the hydrophilicity of the modified surfaces. Methods: Ti6Al4V disks (13-mm diameter) were prepared to evaluate polymer adsorption on the alloy surface. The surface hydrophilicity was evaluated by contact angle (Θ) measurement. Physisorption of polymers on the surface was evaluated quantitatively by a colorimetric method. Results: The largest contact angles were …recorded on samples polished with silicon carbide papers of 1200 and 500 grit (Poli1200 and Poli500 samples: 97.3 ± 4.8 and 84.8 ± 11.0, respectively). Treatment of polished samples with Kroll solution remarkable reduced the contact angles to 46.8 ± 11.6 and 58.6 ± 11.5 for Poli500+Kroll and Poli1200+Kroll, respectively. Contact angles were further reduced in response to PolyNaSS and PAA treatment. Regardless of surface treatment, there was no significant difference in the contact angles on surfaces after SiC 500 and 1200 grit polishing. Conclusions: Physisorbed polymer coatings (such as PAA) on the Ti6Al4V surface can reduce the contact angle and improve the hydrophilicity and wettability of the alloy surface. Moreover, physisorption is a simple technique that does not require any special equipment. Show more

Keywords: Physisorption, colorimetric method, polystyrene sodium sulfonate, polyacrylic acid

DOI: 10.3233/BME-161616

Citation: Bio-Medical Materials and Engineering, vol. 27, no. 6, pp. 657-668, 2016

Authors: Zhang, Cong | Cheng, Yufang | Wang, Haitao | Wang, Chuang | Wilson, Steven P. | Xu, Jiangping | Zhang, Han-Ting

Article Type: Research Article

Abstract: Phosphodiesterase-4 (PDE4) inhibitors enhance memory, increase hippocampal neurogenesis, and reverse amyloid-β (Aβ)-induced memory deficits. Here, we examined whether long-form PDE4D knockdown by lentiviral RNA construct containing a specific microRNA/miRNA-mir hairpin structure (4DmiRNA) reversed memory impairment caused by amyloid-β1-42 (Aβ42 ) in mice using the Morris water maze (MWM) and novelty object recognition tests. Western blotting analysis was used to assess protein levels of cAMP response element-binding protein (CREB, unphosphorylated and phosphorylated [pCREB]), brain-derived neurotrophic factor (BDNF), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and nuclear factor-κB (NF-κB) to explore the neurochemical mechanisms. Aggregated Aβ42 (0.5 μg/side) bilaterally infused in dentate gyrus …decreased cAMP levels (p < 0.01) and produced memory deficits in the MWM (p < 0.01) and object recognition tests (p < 0.01). Microinfusions of lentiviruses resulted in downregulated expression of PDE4D4 and 4D5 proteins and reversed Aβ42 -induced cAMP decline (p < 0.05) and memory deficits. Treatment also concomitantly increased pCREB (p < 0.05) and BDNF (p < 0.01) and reduced IL-1β (p < 0.05), TNF-α (p < 0.01), and NF-κB (p65) (p < 0.05) in the hippocampus of Aβ42 -challenged mice. These results suggest that long-form PDE4D knockdown may offer a promising treatment for memory loss associated with Alzheimer's disease. Show more

Keywords: Alzheimer's disease, anti-inflammation, long-form PDE4D, memory, PDE4

DOI: 10.3233/JAD-122236

Citation: Journal of Alzheimer's Disease, vol. 38, no. 2, pp. 269-280, 2014