IGFBP1

IGFBP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZT3, 1ZT5, 2DSQ
Dynodwyr
Cyfenwau	IGFBP1, AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1, insulin like growth factor binding protein 1
Dynodwyr allanol	OMIM: 146730 HomoloGene: 498 GeneCards: IGFBP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signaling receptor binding • insulin-like growth factor II binding • insulin-like growth factor binding • growth factor binding • insulin-like growth factor I binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • extracellular region • Golgi apparatus • extracellular space • endoplasmic reticulum lumen Prosesau biolegol • PERK-mediated unfolded protein response • tissue regeneration • GO:1901047 insulin receptor signaling pathway • regulation of cell growth • negative regulation of canonical Wnt signaling pathway • GO:0072468 signal transduction • regulation of insulin-like growth factor receptor signaling pathway • positive regulation of cell growth • GO:0010260 heneiddio • post-translational protein modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3484	n/a
Ensembl	ENSG00000146678	n/a
UniProt	P08833	n/a
RefSeq (mRNA)	NM_001013029 NM_000596	n/a
RefSeq (protein)	NP_000587	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IGFBP1 yw IGFBP1 a elwir hefyd yn Insulin like growth factor binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7p12.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IGFBP1.

• AFBP
• IBP1
• PP12
• IGF-BP25
• hIGFBP-1

Llyfryddiaeth

• "High insulin-like growth factor-binding protein-1 (IGFBP-1) is associated with low relative muscle mass in older women. ". Metabolism. 2017. PMID 28732569.
• "Association of Circulating IGFBP1 Level with the Severity of Coronary Artery Lesions in Patients with Unstable Angina. ". Dis Markers. 2017. PMID 28316362.
• "Higher IGFBP-1 to IGF-1 serum ratio predicts unfavourable survival in patients with nasopharyngeal carcinoma. ". BMC Cancer. 2017. PMID 28143425.
• "Influence of glyco-oxidation on complexes between fibrin(ogen) and insulin-like growth factor-binding protein-1 in patients with diabetes mellitus type 2. ". Free Radic Res. 2017. PMID 27919172.
• "IGFBP-1 marker of cervical ripening and predictor of preterm birth.". Med Glas (Zenica). 2016. PMID 27452330.