ANP32A

ANP32A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JE0, 2JE1, 4XOS
Dynodwyr
Cyfenwau	ANP32A, C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32, acidic nuclear phosphoprotein 32 family member A
Dynodwyr allanol	OMIM: 600832 HomoloGene: 133783 GeneCards: ANP32A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • RNA binding • GO:0031493 histone binding Cydrannau o'r gell • cytoplasm • perinuclear region of cytoplasm • Reticwlwm endoplasmig • cnewyllyn cell • nucleoplasm Prosesau biolegol • GO:0007243 intracellular signal transduction • GO:0009373 regulation of transcription, DNA-templated • nucleocytoplasmic transport • transcription, DNA-templated • regulation of mRNA stability • nucleosome assembly • regulation of apoptotic process • GO:0035042 histone exchange Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8125	n/a
Ensembl	ENSG00000140350	n/a
UniProt	P39687	n/a
RefSeq (mRNA)	NM_006305	n/a
RefSeq (protein)	NP_006296	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ANP32A yw ANP32A a elwir hefyd yn Acidic nuclear phosphoprotein 32 family member A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ANP32A.

• LANP
• MAPM
• PP32
• HPPCn
• PHAP1
• PHAPI
• I1PP2A
• C15orf1

Llyfryddiaeth

• "Involvement of hepatopoietin Cn in the development of human hepatocellular carcinoma. ". Clin Exp Metastasis. 2010. PMID 20683644.
• "Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women. ". Arthritis Rheum. 2009. PMID 19565487.
• "Acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) association with lymph node metastasis predicts poor survival in oral squamous cell carcinoma patients. ". Oncotarget. 2016. PMID 26918356.
• "High-resolution crystal structure of the leucine-rich repeat domain of the human tumour suppressor PP32A (ANP32A). ". Acta Crystallogr F Struct Biol Commun. 2015. PMID 26057796.
• "Highly polarized C-terminal transition state of the leucine-rich repeat domain of PP32 is governed by local stability.". Proc Natl Acad Sci U S A. 2015. PMID 25902505.