PIP5K1C

PIP5K1C
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2G35, 3H1Z, 3H85
Dynodwyr
Cyfenwau	PIP5K1C, LCCS3, PIP5K-GAMMA, PIP5K1-gamma, PIP5Kgamma, phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
Dynodwyr allanol	OMIM: 606102 HomoloGene: 69032 GeneCards: PIP5K1C
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • kinase activity • GO:0001948, GO:0016582 protein binding • phosphatidylinositol phosphate kinase activity • ATP binding • phosphatidylinositol-3,4-bisphosphate 5-kinase activity • 1-phosphatidylinositol-4-phosphate 5-kinase activity • 1-phosphatidylinositol-3-phosphate 4-kinase activity Cydrannau o'r gell • cytoplasm • cell projection • bilen • focal adhesion • adherens junction • Cellbilen • ruffle membrane • cell junction • uropod • phagocytic cup • endomembrane system • cnewyllyn cell • presynapse • synapse • nucleoplasm • cytosol • endosome membrane Prosesau biolegol • endocytosis • phosphatidylinositol metabolic process • adherens junction assembly • phosphorylation • synaptic vesicle exocytosis • neutrophil chemotaxis • chemotaxis • clathrin-dependent endocytosis • phosphatidylinositol phosphate biosynthetic process • cell adhesion • synaptic vesicle endocytosis • ffagocytosis • phosphatidylinositol biosynthetic process • actin cytoskeleton organization • exocytosis • regulation of phosphatidylinositol 3-kinase signaling • membrane organization • cell-cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23396	n/a
Ensembl	ENSG00000186111	n/a
UniProt	O60331	n/a
RefSeq (mRNA)	NM_001195733 NM_001300849 NM_012398	n/a
RefSeq (protein)	NP_001182662 NP_001287778 NP_036530	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PIP5K1C yw PIP5K1C a elwir hefyd yn Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PIP5K1C.

• LCCS3
• PIP5Kgamma
• PIP5K-GAMMA
• PIP5K1-gamma

Llyfryddiaeth

• "Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer. ". Breast Cancer Res. 2010. PMID 20074374.
• "Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting. ". Biochem J. 2009. PMID 19548880.
• "Phosphorylation of phosphatidylinositol 4-phosphate 5-kinase γ by Akt regulates its interaction with talin and focal adhesion dynamics. ". Biochim Biophys Acta. 2015. PMID 26149501.
• "PIPKIγ targets to the centrosome and restrains centriole duplication. ". J Cell Sci. 2014. PMID 24434581.
• "PIPKIγ regulates focal adhesion dynamics and colon cancer cell invasion.". PLoS One. 2011. PMID 21931851.