Edinburgh Medical School
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One Health is the approach underpinning the research done at the Edinburgh Medical School. The modern challenges that face not only the UK but the world in terms of the rise of chronic disease, the shifts in populations and the challenges presented by a population which is living much longer are common and the mechanisms underpinning them are common. The aim of the School is to bring the right individuals together to catalyse and create the opportunities to really develop exciting and cutting edge clinical and non-clinical research that makes a difference to people’s lives.
Image: CC-BY Mikhael, S doi.org/10.7488/ds/1983
Sub-communities within this community
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Molecular, Genetic and Population Health Sciences
Inc the IGC (Institute of Genetics and Cancer) and the Usher Institute
Collections in this community
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John West's Research Group
Corneal epithelium research
Recent Submissions
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Blood-based epigenome-wide association study and prediction of alcohol consumption
This dataset corresponds to the study “Blood-based epigenome-wide association study and prediction of alcohol consumption”. Files within this dataset include summary statistics for two Epigenome-wide association studies ... -
Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones
These are the source data underlying the RNA sequencing figures (Figure 2 and 3) presented in a manuscript entitled "Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones", ... -
Targeting TRPM3 As a Potential Therapeutic Approach for Autosomal Dominant Polycystic Kidney Disease
Abstract Cystic diseases, especially autosomal dominant polycystic kidney disease (ADPKD; incidence approx. 1/1000), are a leading cause of renal failure, caused by appearance and growth of renal cysts that can lead ... -
Human metapneumovirus associated acute respiratory infections burden in older adults globally
Background: The human metapneumovirus (hMPV)- associated disease burden in older adults remains under-researched. This review aimed to systematically estimate the global burden of hMPV-associated disease in older ... -
The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure
These are the source data underlying the figures presented in the manuscript accepted in Nature Communications. These are the source data underlying the figures presented in a manuscript entitled "The NE/AAT/CBG axis ... -
Mouse Embryo Developmental Age Stage Selector
Mouse embryos can be staged according to a variety of criteria, the most general of which are those described by Theiler (1989). However, Theiler’s criteria are too broad to distinguish many of the important phases of early ... -
SUPERSEDED - The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/7857 ## These are the source data underlying the figures presented in the manuscript accepted in Nature Communications. These are ... -
SUPERSEDED - The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/7857 ## These are the source data underlying the figures presented in the manuscript accepted in Nature Communications. These are ... -
Dataset for `Neutrophils have a temporal dichotomous role in acute liver injury and repair` - AT7519 neutrophil depletion
Whole Liver from WT mice, 36 hours after 350mg/kg paracetamol i.p/ having received either 30mg/kg AT7159 or vehicle i.p. at 16 hours post. 36 hours is repair time point in this model, with 16 hours being peak ... -
Dataset for `Neutrophils have a temporal dichotomous role in acute liver injury and repair` - FPR1-/-
Whole Liver from FPR1-/- and WT mice 24 hours post treatment with paracetamol 350mg/kg Nanostring mouse myeloid panel gene set with additional 10 gene spike (see attached documents) -
Genome-wide chromosome architecture prediction reveals biophysical principles underlying gene structure
Data associated with the paper: Michael Chiang, Chris A Brackley, Catherine Naughton, Ryu-Suke Nozawa, Cleis Battaglia, Davide Marenduzzo, Nick Gilbert (in press). Genome-wide chromosome architecture prediction reveals ... -
Data supporting Davies & Beadman (2025) "Self-organization, error-correction and homeorhesis in renal development"
The dataset consists of one slide deck in pdf format; within the slide deck there are two sections, each supporting one sentence in the paper referred to in the title of this data set. Development is often described as ... -
DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts
This dataset corresponds to the study: "DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts". Files within this dataset include summary statistics from epigenome-wide association studies ... -
Klebsiella variicola dataset
This dataset of Klebsiella variicola contains 715 genome files categorised as human, animal, plant or environmental-associated strains. This dataset was used to study the population structure, evolutionary dynamics, ... -
Synaptic interactions between stellate cells and parvalbumin interneurons in layer 2 of the medial entorhinal cortex are organized at the scale of grid cell clusters
Electrophysiological and anatomical datasets, analysed data and code for experiments described in Huang et al., Synaptic interactions between stellate cells and parvalbumin interneurons in layer 2 of the medial entorhinal ... -
Klebsiella pneumoniae dataset
This dataset of Klebsiella pneumonia contains 1000 genome files randomly selected from NCBI. This dataset was built for comparative analysis with the Klebsiella variicola dataset. -
Dataset: Adiponectin influences the effects of caloric restriction on liver function, skeletal muscle, and systemic metabolic homeostasis _v2024_09_19
This dataset contains data for a manuscript that is being submitted for publication in September 2024. Once published, this dataset will be updated with the DOI for the manuscript. The Abstract for the current version of ... -
Supplementary files from manuscript "Limiting pre-menstrual endometrial Hypoxia Inducible Factor 2 Alpha may fine-tune endometrial function at menstruation"
Heavy menstrual bleeding (HMB) is common and debilitating, but the precise endometrial mechanisms causing increased menstrual blood loss (MBL) remain undefined. We have previously identified a role for hypoxia in endometrial ... -
Activity-induced filopodia form at the presynapse and enclose SV fusion.
The combination of synaptic structural stability and functional plasticity is a recognized feature of the nervous system. This dichotomy is possible because the processes involved in neuronal information processing, such ... -
Temporal coupling of axonal calcium responses and filopodia formation
The combination of synaptic structural stability and functional plasticity is a recognized feature of the nervous system. This dichotomy is possible because the processes involved in neuronal information processing, such ...
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