The University of Edinburgh’s College of Medicine & Veterinary Medicine is an international leader in basic-to-clinical translational research. The College's research ranges from bench to bedside and from process to population. Research themes are: genes and populations, normal and diseased cells and inflammation and tissue repair.

The University is one of the oldest centres for medical and veterinary medical research in the UK. It is also one of the most dynamic and progressive, with state of the art facilities across the College. The 2021 Research Excellence Framework (REF) results reaffirmed the College’s reputation as one of the world’s leading centres of medical and veterinary medical research.

College of Medicine & Veterinary Medicine

Sub-communities within this community

Recent Submissions

  • Blood-based epigenome-wide association study and prediction of alcohol consumption 

    Bernabeu, Elena; Chybowska, Aleksandra D; Kresovich, Jacob K; Suderman, Matthew; McCartney, Daniel L; Hillary, Robert F; Corley, Janie; Valdés-Hernández, Maria Del C; Muñoz Maniega, Susana; Bastin, Mark E; Wardlaw, Joanna M; Xu, Zongli; Sandler, Dale P; Campbell, Archie; Harris, Sarah E; McIntosh, Andrew M; Taylor, Jack A; Yousefi, Paul; Cox, Simon R; Evans, Kathryn L; Robinson, Matthew R; Vallejos, Catalina A; Marioni, Riccardo E
    This dataset corresponds to the study “Blood-based epigenome-wide association study and prediction of alcohol consumption”. Files within this dataset include summary statistics for two Epigenome-wide association studies ...
  • Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones 

    Nixon, Mark; Ivatt, Lisa; Paul, Mhairi; Hadoke, Patrick; Bailey, Matthew; Morgan, Ruth
    These are the source data underlying the RNA sequencing figures (Figure 2 and 3) presented in a manuscript entitled "Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones", ...
  • SV2A is expressed in subpopulations of mouse and human synapses 

    Wong, Theresa; Qiu, Zhen; Notman, Beverly; Tavares, Adriana; Smith, Colin; Grant, Seth GN
    Synapse pathology is a feature of most brain diseases and there is a pressing need to monitor the onset and progression of this pathology using brain imaging in living patients. A major step toward this goal has been the ...
  • Targeting TRPM3 As a Potential Therapeutic Approach for Autosomal Dominant Polycystic Kidney Disease 

    Gul, Huseyin
    Abstract Cystic diseases, especially autosomal dominant polycystic kidney disease (ADPKD; incidence approx. 1/1000), are a leading cause of renal failure, caused by appearance and growth of renal cysts that can lead ...
  • Human metapneumovirus associated acute respiratory infections burden in older adults globally 

    Kulkarni, Durga; Nair, Harish
    Background: The human metapneumovirus (hMPV)- associated disease burden in older adults remains under-researched. This review aimed to systematically estimate the global burden of hMPV-associated disease in older ...
  • The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure 

    Nixon, Mark; Boyle, Luke; Miguelez-Crespo, Allende; Paul, Mhairi; Villalobos, Elisa; Nagy, Boglarka; Homer, Natalie; Magennis, Marisa; Andrew, Ruth; Stimson, Roland; Walker, Brian
    These are the source data underlying the figures presented in the manuscript accepted in Nature Communications. These are the source data underlying the figures presented in a manuscript entitled "The NE/AAT/CBG axis ...
  • Mouse Embryo Developmental Age Stage Selector 

    Davidson, Duncan; Baldock, Richard; Venkataraman, Shanmugasundaram; Lawson, Kirstie; Wilson, Valerie
    Mouse embryos can be staged according to a variety of criteria, the most general of which are those described by Theiler (1989). However, Theiler’s criteria are too broad to distinguish many of the important phases of early ...
  • SUPERSEDED - The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure 

    Nixon, Mark; Boyle, Luke; Paul, Mhairi; Miguelez-Crespo, Allende; Villalobos, Elisa; Nagy, Boglarka; Homer, Natalie; Magennis, Marisa; Andrew, Ruth; Stimson, Roland; Walker, Brian
    ## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/7857 ## These are the source data underlying the figures presented in the manuscript accepted in Nature Communications. These are ...
  • Post-concussion symptom burden and dynamics: insights from a digital health intervention and machine learning 

    Jamjoom, Aimun; d'Offay, Christine; Gillespie, David; Reed, Matthew
    Raw HeadOn symptom burden data for 84 study participants. Participants were invited to rate a total of 8 post-concussion symptoms over the 35 day digital HeadOn program. Each symptom was rated on a Likert scale (0 = no ...
  • SUPERSEDED - The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure 

    Boyle, Luke; Paul, Mhairi; Nagy, Boglarka; Villalobos, Elisa; Homer, Natalie; Magennis, Marisa; Andrew, Ruth; Stimson, Roland; Walker, Brian; Miguelez-Crespo, Allende; Nixon, Mark
    ## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/7857 ## These are the source data underlying the figures presented in the manuscript accepted in Nature Communications. These are ...
  • INSIDE-HIV: imaging neuroinflammation in severe and persistent depression in people with HIV 

    Mudra Rakshasa-Loots, Arish; Diteko, Goabaone; Dowell, Nicholas G; Ronen, Itamar; Vera, Jaime H
    This dataset contains data generated for the INSIDE-HIV study, carried out at Brighton & Sussex Medical School (BSMS), University of Sussex, Brighton, UK. The objective of this pilot study was to assess whether neuroinflammation ...
  • Dataset for `Neutrophils have a temporal dichotomous role in acute liver injury and repair` - AT7519 neutrophil depletion 

    Cartwright, Jennifer; Rossi, Adriano G; Potey, Philippe MD; Livingstone, Eilidh; Campana, Lara; Starkey Lewis, Philip J; Oremek, Magdalena EM; Gachanja, Naomi; Rinaldi, Giulia; Aird, Rhona E; Yung Man, Tak; Fernando, Anuruddika J; Simpson, Joanna P; Homer, Natalie ZM; Barth, Nicole; Addison, Melisande; Ashmore-Harris, Candice; Candela, Maria Elena; Kilpatrick, Alastair M; Vermeren, Matthieu; Robb, Calum T; Dorward, David A; Lucas, Christopher D; Forbes, Stuart J
    Whole Liver from WT mice, 36 hours after 350mg/kg paracetamol i.p/ having received either 30mg/kg AT7159 or vehicle i.p. at 16 hours post. 36 hours is repair time point in this model, with 16 hours being peak ...
  • Dataset for `Neutrophils have a temporal dichotomous role in acute liver injury and repair` - FPR1-/- 

    Cartwright, Jennifer; Rossi, Adriano G; Potey, Philippe MD; Livingstone, Eilidh; Campana, Lara; Starkey Lewis, Philip J; Oremek, Magdalena EM; Gachanja, Naomi; Rinaldi, Giulia; Aird, Rhona E; Yung Man, Tak; Fernando, Anuruddika J; Simpson, Joanna P; Homer, Natalie ZM; Barth, Nicole; Addison, Melisande; Ashmore-Harris, Candice; Candela, Maria Elena; Kilpatrick, Alastair M; Vermeren, Matthieu; Robb, Calum T; Dorward, David A; Lucas, Christopher D; Forbes, Stuart J
    Whole Liver from FPR1-/- and WT mice 24 hours post treatment with paracetamol 350mg/kg Nanostring mouse myeloid panel gene set with additional 10 gene spike (see attached documents)
  • Genome-wide chromosome architecture prediction reveals biophysical principles underlying gene structure 

    Chiang, Michael; Brackley, Chris A; Naughton, Catherine; Nozawa, Ryu-Suke; Battaglia, Cleis; Marenduzzo, Davide; Gilbert, Nick
    Data associated with the paper: Michael Chiang, Chris A Brackley, Catherine Naughton, Ryu-Suke Nozawa, Cleis Battaglia, Davide Marenduzzo, Nick Gilbert (in press). Genome-wide chromosome architecture prediction reveals ...
  • Data supporting Davies & Beadman (2025) "Self-organization, error-correction and homeorhesis in renal development" 

    Davies, Jamie; Beadman, Rhiannon
    The dataset consists of one slide deck in pdf format; within the slide deck there are two sections, each supporting one sentence in the paper referred to in the title of this data set. Development is often described as ...
  • Raw red counts from a CRISPR screen for host factors required for influenza virus replication 

    Li, Bo; Clohisey, Sara M; Chia, Bing Shao; Wang, Bo; Cui, Ang; Eisenhaure, Thomas; Schweitzer, Lawrence D; Hoover, Paul; Parkinson, Nicholas J; Nachshon, Aharon; Smith, Nikki; Regan, Tim; Farr, David; Gutmann, Michael U; Bukhari, Syed Irfan; Law, Andrew; Sangesland, Maya; Gat-Viks, Irit; Digard, Paul; Vasudevan, Shobha; Lingwood, Daniel; Dockrell, David H; Doench, John G; Baillie, J Kenneth; Hacohen, Nir
    Raw data for the CRISPR screen we conducted in collaboration with Bo Li, John Doench and Nir Hacohen can be downloaded here. Please refer to the manuscript for full details: [doi.org/10.1038/s41467-019-13965-x] Host ...
  • DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts 

    Smith, Hannah M; Ng, Hong Kiat; Moodie, Joanna E; Gadd, Danni A; McCartney, Daniel L; Bernabeu, Elena; Campbell, Archie; Redmond, Paul; Taylor, Adele; Page, Danielle; Corley, Janie; Harris, Sarah E; Tay, Darwin; Deary, Ian J; Evans, Kathryn L; Robinson, Matthew R; Chambers, John C; Loh, Marie; Cox, Simon R; Marioni, Riccardo E; Hillary, Robert F
    This dataset corresponds to the study: "DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts". Files within this dataset include summary statistics from epigenome-wide association studies ...
  • Klebsiella variicola dataset 

    Wang, Jiayu; Coipan, Claudia; Franz, Eelco; Kuijper, Ed; Wessels, Els; Gally, David; Vasudevan, Karthick; Veerarhagavan, Balaji; Farzana, Refath; Holden, Nicola; Zadoks, Ruth N; Higgins, Paul G; Schneiders, Thamarai
    This dataset of Klebsiella variicola contains 715 genome files categorised as human, animal, plant or environmental-associated strains. This dataset was used to study the population structure, evolutionary dynamics, ...
  • Synaptic interactions between stellate cells and parvalbumin interneurons in layer 2 of the medial entorhinal cortex are organized at the scale of grid cell clusters 

    Huang, Li-Wen; Garden, Derek; Nolan, Matthew
    Electrophysiological and anatomical datasets, analysed data and code for experiments described in Huang et al., Synaptic interactions between stellate cells and parvalbumin interneurons in layer 2 of the medial entorhinal ...
  • Klebsiella pneumoniae dataset 

    Wang, Jiayu; Coipan, Claudia; Franz, Eelco; Kuijper, Ed; Wessels, Els; Gally, David; Vasudevan, Karthick; Veerarhagavan, Balaji; Farzana, Refath; Holden, Nicola; Zadoks, Ruth N; Higgins, Paul G; Schneiders, Thamarai
    This dataset of Klebsiella pneumonia contains 1000 genome files randomly selected from NCBI. This dataset was built for comparative analysis with the Klebsiella variicola dataset.

View all